Other Peptides

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A2727 N-Acetyl-Adhesin Amide Fragment 1025-1044 ≥95% (HPLC) Antimicrobial peptide that has been shown to specifically inhibit binding of a cell surface adhesion of Streptococcus mutans, the main etiological agent of dental caries, to salivary receptors in vitro.
    • A0710 N-Acetyl-Ala-Glu-Tyr-Tyr-Asn-Lys-Gln-Tyr-Leu-Glu-Gln-Thr-Arg-Ala-Glu-Leu-Asp-Thr amide ≥90% (HPLC) Prevents experimental autoimmune encephalomyelitis in mice
    • A0936 N-Acetylmuramyl-Ala-D-isoglutaminyl-Nε-stearoyl-Lys Antibiotic peptide.
    MDP-LYS(L18), a synthetic analogue of MDP (muramyl dipeptide) derived from bacterial cell walls, is used as a potent immunoadjuvant that enhances protective immunity through activation of monocyte-macrophage lineage cells, such as dendritic cells.
    N-Acetylmuramyl-Ala-D-isoglutaminyl-Nε-stearoyl-Lys, Romurtide, a muramyl dipeptide analogue, is a granulocyte-macrophage colony-stimulating factor and a TNF-α inducer.
    • A9519 N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate ≥98% (TLC) Enhances antigenicity of weak antigens, increasing antibody titer.
    N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.
    • R5380 N-Acetyl-Renin Substrate Tetradecapeptide porcine ≥97% (HPLC)  
    • A1085 N-Acetyl-Tyr-Val-Ala-Glu-al ≥98% (TLC)  
    • T8156 Adrenorphin ≥95% (HPLC)  
    • A5025 Ala-Ala-Ala-Ala-Ala  
    • A0910 Ala-D-γ-Glu-Lys-D-Ala-D-Ala ≥97% (HPLC) L-Ala-D-Glu-gamma-L-Lys-D-Ala-D-Ala, peptidoglycan pentapeptide, is the antigenic peptide determinant of peptidoglycan useful in studies of mechanisms of action of glycopeptide antibiotics.
    • A3546 Ala-Leu-Ala-Leu ≥97% (HPLC) A peptidase labile sequence used to link drugs to proteins or lipophilic carriers.
    Ala-Leu-Ala-Leu (ALAL), a peptidase labile (cathepsin B) prodrug linker, is used to link bioavailable drugs to protein carriers such as albumin.
    • A7060 Ala-Lys-Pro-Ser-Tyr-Hyp-Hyp-Thr-Tyr-Lys ≥97% (HPLC) Bioadhesive peptide
    • A7185 Ala-Lys(TFA)-Pro-Ser-Tyr-Hyp-Hyp-Thr-Tyr-Lys ≥97% (HPLC) Bioadhesive peptide
    • A9554 Allatostatin IV ≥97% (HPLC) Allatostatin IV, an octapeptide amine, is a member of the allatoregulatory peptide family found in insects which either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis.
    Inhibitor of juvenile hormone synthesis in insects.
    • A2602 Asn-Arg-Cys-Ser-Gln-Gly-Ser-Cys-Trp-Asn, Reduced ≥85% (HPLC) The activity of the enzymes protein disulfide-isomerase (PDI) and DsbA (a periplasmic protein thiol:disulfide oxidoreductase) can be monitored with this peptide. Oxidation of this dithiol peptide to the disulfide state is accompanied by a significant change in tryptophan fluorescence emission intensity. This permits the rapid determination of the pH-dependence of the activity of both enzymes.
    • A5667 Asp-Ala-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val ≥97% (HPLC)  
    • A4440 Asp-Asp-Asp-Asp ≥97% (TLC) Tetraaspartic acid (Asp-Asp-Asp-Asp) is a small polyanionic peptide used in physicochemical studies along with other polyanionic peptides. Tetraaspartic acid forms complexes with metals such as copper making it useful in studies on copper mediated effects such as free radial formation.
    • B7510 Beauvericin ≥97% (HPLC) Beauvericin (BEA), a cyclohexadepsipeptide produced by the fungus Beauveria bassiana (Bals.), has antiviral, antibacterial, nematicidal, insecticidal, cytotoxic, and apoptotic activity.
    • 15560 Bombesin acetate salt hydrate ≥97.0% (HPLC)  
    • B4139 Bovine adrenal medulla dodecapeptide ≥97% (HPLC)  
    • BRAINPEP Brain Peptide Kit  
    • C9026 Caerulein ≥97% (HPLC) Caerulein is a gastroregulatory molecule with actions similar to cholecystokinin. Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer.
    Effects on perception of pain are conflicting. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication; however, in general, it is seen as an antagonist of endogenous opioids.
    • C7278 Caseinoglycopeptide from bovine casein essentially salt-free, lyophilized powder The soluble carboxyl-terminal moiety of κ-casein. This antithrombotic peptide binds to glycoprotein GPIb in the platelet membrane, thus inhibiting platelet aggregation by blocking the binding of von Willebrand factor.
    • C2795 Acetyl-[Tyr(SO3H)27]-Cholecystokinin fragment 26-31 Amide ≥97% (HPLC)  
    • C9524 Acetyl-[Tyr(SO3H)27]-Cholecystokinin fragment 27-33 Amide ≥95% (HPLC)  
    • CCK2 Cholecystokinin Peptide Kit 2  
    • C2921 Corazonin ≥97% (HPLC) Cardioaccelerating peptide originally isolated from the corpus cardiacum of the American cockroach; the most potent insect cardioactive neuropeptide.
    • C246 Corticotropin Releasing Factor Antagonist ≥97% (HPLC), powder The corticotropin releasing factor (CRF) antagonist α-helical CRF [9-41] exhibits 10-fold higher affinity for rat CRF2α receptors over human CRF2α receptors. It has been used to elucidate the role of CRF in various physiological systems. In colonic epithelium, it abolishes CRF-induced changes in ion secretion, and significantly inhibits CRF-stimulated conductance. It antagonizes the CRF-induced proinflammatory degranulation of perivascular mast cells that are activated in response to acute psychological stress and CRF secretion.
    • C9357 Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) ≥96% (HPLC) Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.
    Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.
    • C1307 Cyclo(D-Glu-Ala-D-allo-Ile-Leu-D-Trp) ≥97% (HPLC) Selective ETA endothelin receptor antagonist.
    • C6922 Cyclohexylacetyl-Phe-Arg-Ser-Val-Gln amide ≥97% (HPLC)  
    • E9384 [Cys(Acm)20,31]-Epidermal Growth Factor Fragment 20-31 ≥97% (HPLC) The fragment of mouse epidermal growth factor (EGF) that contains the receptor-binding region as well as the predominant EGF antigenic determinant. This fragment exhibits the biological activity of EGF in vitro.
    • F3635 Fibroblast Growth Factor, Acidic, Fragment 1-11 bovine ≥97% (HPLC)  
    • 47729 N-Formyl-Met-Leu-Phe BioXtra, ≥99.0% (TLC) N-Formyl-Met-Leu-Phe is a potent chemotactic peptide and formyl peptide receptor (FPR) agonist that induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
    Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
    • 47732 N-Formyl-Met-Leu-Phe ≥97.0% (HPLC) Potent chemotactic peptide.1 Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.2
    • G3882 Gly-Gly-Gly-Gly Tetraglycine is used with copper (Cu-II) to study mechanisms of hydrogen peroxide/bicarbonate free radical production and effect in vitro.
    • 87300 Gly-Gly-Gly-Gly purum, ≥98.0% (TLC)  
    • G9031 Gly-Val-Leu-Ser-Asn-Val-Ile-Gly-Tyr-Leu-Lys-Lys-Leu-Gly-Thr-Gly-Ala-Leu-Asn-Ala-Val-Leu-Lys-Gln trifluoroacetate salt ≥95% (HPLC) Antimicrobial peptide originally isolated from Xenopus laevis.
    • G7897 Granuliberin R ≥97% (HPLC) Mast cell degranulating peptide found in the skin of the frog, Rana rugosa.
    • L7404 Histatin 8 ≥95% (HPLC) Hemagglutination inhibiting peptide originally isolated from human parotid saliva
    • H4162 Human Parainfluenza Virus Type 3, fusion protein, fragment 454-488, acetylated  
    • I123 ICI 216,140 >95%, solid Potent in vivo receptor antagonist of the bombesin/gastrin releasing peptide receptor.
    • I3263 Insulin-like Growth Factor-II fragment 33-40 ≥97% (HPLC)  
    • K4388 Kinase Domain of Pyruvate Kinase porcine ≥95% (HPLC)  
    • L7783 Leu-Arg-Arg-Asp-Leu-Asp-Ala-Ser-Arg-Glu-Ala-Lys-Lys-Gln-Val-Glu-Lys-Ala-Leu-Glu ≥97% (HPLC)  
    • L5538 Leu-Ser-Lys-Leu-NH2 ≥95% (HPLC) Leu-Ser-Lys-Leu-NH2 (LSKL-NH2) is found at the C-terminal of the neurotoxic wasp venom α-pompilidotoxin (α-PMTX). A similar peptide Leu-Ser-Lys-Leu (LSKL) is a used to study the activation of TGF-β1 via thrombospondin.
    Used to study the activation of TGF-β1
    • L2031 Leu-Ser-Ser-Phe-Val-Arg-Ile amide acetate salt ≥97% (HPLC)  
    • L1658 Locustapyrokinin from Locusta migratoria ≥97% (HPLC)  
    • L2776 Lys-Gln-Ala-Gly-Asp-Val ≥97% (HPLC) Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.
    • L9026 Lys-Lys-Lys-Lys ≥95% (TLC) Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.
    • L9151 Lys-Lys-Lys-Lys-Lys ≥55% peptide basis Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.
    • M1170 Met-Arg-Phe-Ala acetate salt ≥90% (HPLC)  
    • M4786 Met-Gly-Met-Met ≥97% Met-Gly-Met-Met is a peptide substrate.
    • E5131 [des-Tyr1, D-Ala2]-Methionine enkephalinamide acetate salt ≥95% (HPLC)  
    • SML0195 Mifamurtide ≥98% (HPLC) Mifamurtide (Muramyl tripeptide phosphatidylethanolamine; MTP-cephalin; MTP-PE) is a synthetic, lipophilic analog of muramyl dipeptide. It acts as an immunostimulant promoting cancer cell destruction via in vivo macrophage activation.
    • M4046 Mitogen-Activated Protein Kinase 2 fragment 326-339 ≥97% (HPLC)  
    • M7530 [Leu13]-Motilin porcine ≥97% (HPLC) [Leu13]-Motilin porcine exhibits gastric motor stimulating activity.
    • P0995 [pSer8]-Myelin Basic Protein Fragment 5-15 trifluoroacetate salt ≥90% (HPLC)  
    • M4449 Myelin Oligodendrocyte Glycoprotein (35-55), Human lyophilized powder This is a truncated peptide from the human Myelin Oligodendrocyte Glycoprotein (MOG) responsible for the induction of experimental autoimmune encephalomyelitis in mouse and rat models for human multiple sclerosis research.
    • M4939 Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 Rat, Mouse immunodominant epitope of MOG Induces experimental autoimmune encephalomyelitis in rodents; a single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination; immunization with MOG (35-55) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP.
    Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 induces experimental autoimmune encephalomyelitis in rodents; a single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination; immunization with MOG (35-55) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP.
    • M4199 Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse lyophilized powder The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.
    • M4324 Myelin Oligodendrocyte Glycoprotein (44-54), Rat, Mouse lyophilized powder The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.
    • N190 [D-Tyr27,36, D-Thr32]-Neuropeptide Y fragment 27-36, rat >97%, lyophilized powder [D-Tyr27,36, D-Thr32]-Neuropeptide Y fragment 27-36, rat is neurotransmitter.
    • A228 Nle-Antiflammin-2  
    • N0909 Nociceptin Fragment 1-7 Reduces nociceptin-induced hyperalgesia in mice. This endogenously formed N-terminal fragment may modulate the hyperalgesic action of nociceptin in the spinal cord.
    • P3116 [pSer392]-p53 >90% (HPLC), solid Positive control peptide for the [Ser392]-p53 rabbit polyclonal antibody.
    • 670820 Pam3-Cys-OH ≥98.0% (TLC)  
    • P0435 Pardaxin ≥97% (HPLC) Induces neurotransmitter release
    • P0175 pGlu-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2 ≥95% (HPLC) Hypertrehalosemic neuropeptide from cockroach (Nauphoeta cinerea) with an amino acid sequence similar to that of adipokinetic hormone; involved in carbohydrate metabolism and increases the trehalose content of hemolymph.
    Glp-Val-Asn-Phe-Ser-Pro-Gly-Trp-Gly-Thr-NH2 is a hypertrehalosemic neuropeptide (Nauphoeta cinerea) has an amino acid sequence similar to that of adipokinetic hormone and is involved in carbohydrate metabolism and increases the trehalose content of hemolymph.
    • P3708 Phe-Gln-Val-Val-Cys(NPYS)-Gly-NH2 ≥95% (HPLC) Selectively blocks thrombin-induced platelet aggregation by binding to platelet calpain. Does not inhibit platelet aggregation induced by hemostasis factors other than thrombin.
    • P5523 Phe-Leu-Glu-Glu-Leu ≥97% (HPLC)  
    • P5398 Phe-Leu-Glu-Glu-Val ≥97% (HPLC)  
    • P3293 Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide ≥95% (HPLC) Attenuates analgesic effects of morphine
    • P3121 Phe-Phe-Phe-Phe-Phe acetate salt ≥97% (HPLC)  
    • P5963 Platelet-derived Growth Factor β−Receptor Fragment 742-758 ≥95% (HPLC)  
    • P3616 [pTyr783]-PLCγ ≥80% (HPLC), solid Positive control peptide for the [Tyr783]-PLCγ rabbit polyclonal antibody.
    • P3741 [Tyr783]-PLCγ ≥80% (HPLC), solid Negative control peptide for the [pTyr783]-PLCγ rabbit polyclonal antibody.
    • P2076 Polymyxin B nonapeptide hydrochloride cationic cyclic peptide Polymyxin B nonapeptide (PMBN), a cationic cyclic peptide derived from the antibacterial peptide polymyxin B, specifically increases the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics.1,2,3 PMBN has been used to evaluate multidrug efflux inhibitors in E. coli.4
    Polymyxin B nonapeptide hydrochloride is a derivative of PMB that induces outer membrane permeability in gram-negative bacteria.
    • P5818 Protein C, Activated, Fragment 390-404 human ~90% (HPLC) Fragment of activated protein C (APC) heavy chain that is essential for anticoagulant activity.
    • P2655 [Tyr52, Asp76]-PTH Fragment 52-84 human ≥97% (HPLC)  
    • R9002 Ranatensin ≥95% (HPLC)  
    • SRP3147 Relaxin-2 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.
    • R8129 Renin Substrate Tetradecapeptide porcine ≥97% (HPLC)  
    • S8649 Sar-Arg-Gly-Asp-Ser-Pro ≥97% (HPLC)  
    • S7152 Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe ≥97% (HPLC) Thrombin receptor activator
    • S8701 SFLLR-NH2 trifluoroacetate salt ≥95% (HPLC), powder SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.
    • S5440 [Ser727]-STAT3 ≥85% (HPLC)  
    • GASTRINS Synthetic Gastrin Kit  
    • T7821 [Ser409]-Tau >85% (HPLC)  
    • T8786 Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala ≥97% (HPLC)  
    • T8806 Thymopentin ≥97% (HPLC)  
    • T8661 Transforming Growth Factor-α Fragment 34-43 Rat ≥97% (HPLC)  
    • T5897 Tuftsin acetate salt hydrate ≥97% (HPLC)  
    • T1292 Tumor Necrosis Factor-α Human Fragment 46-65 ≥95% (HPLC)  
    • T8455 Tyrosinase Fragment 369-377 human The Tyrosinase enzyme catalyzes the first steps in the conversion of tyrosine to melanin. This is a membrane bound enzyme expressed in primary and metastatic melanoma lesions. The Tyrosine fragment 369-377 peptide is presented by HLA-A2 antigen to CTLs.
    • T5517 Tyr-D-Trp-Ala-Trp-D-Phe amide ≥95% (HPLC) Releases growth hormone from rat pituitary in vitro.
    • U118 [Tyr0]Urocortin, rat  
    • V0883 Val-Ala-Pro-Gly acetate salt ≥97% (HPLC)  
    • V6505 Valosin Porcine ≥97% (HPLC) Stimulates pancreatic secretion.
    • V0879 [pGlu16]-Vasoactive Intestinal Peptide Fragment 16-28 Chicken ≥97% (HPLC)  
    • V7009 [Arg8]-Vasotocin-Gly-Lys ≥97% (HPLC)  
    • V1258 [Arg8]-Vasotocin-Gly-Lys-Arg ≥97% (HPLC)  
    • C9415 Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Nε-Boc-Lys methyl ester ≥85% (HPLC) Primate-specific renin inhibitor with prolonged duration of action.