Antibodies for Parkinson’s Disease Research

Parkinson′s Disease (PD) is a slowly progressing motor system neurodegeneration characterized by akinesia, rigidity, postural instability, and resting tremor. Cognitive and behavioral problems may result, in addition to dementia in the advanced stages. Onset is typically after the age of 50. The motor symptoms of PD, known collectively as Parkinsonism, are caused by the loss of dopaminergic cell bodies in the substantia nigra resulting in a reduced supply of dopamine to the basal ganglia. There is also notable accumulation of a protein called alpha-synuclein into inclusions (Lewy bodies) in neurons. Research has determined that some cases of PD may have genetic or environmental causes. Drugs that increase levels of dopamine can be used to treat the early motor symptoms of PD, but as the disease advances, their effectiveness declines.

Sigma-Aldrich offers a broad range of antibodies for use in Parkinson′s Disease research.

Product #

Description

Clone

Form

Gene Symbol (ID)

Species Reactivity

Application

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A9607 Anti-ATP13A2 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... ATP13A2(23400)
mouse ... Atp13a2(74772)
rat ... Atp13a2(362645)
human, mouse
WB
WH0023400M6 Monoclonal Anti-ATP13A2 antibody produced in mouse 4B7, monoclonal
purified immunoglobulin
human ... ATP13A2(23400)
human
ELISA (i), WB
A9732 Anti-ATP13A2 (C-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... ATP13A2(23400)
mouse ... Atp13a2(74772)
mouse, human
WB
A3361 Anti-ATP13A2 (C-terminal region) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... ATP13A2(23400)
human, mouse
WB
C8487 Anti-Caspase 3, Active antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... CASP3(836)
mouse ... Casp3(12367)
rat ... Casp3(25402)
bovine, mouse, rat, canine, human, pig
ARR, IF, WB
C7729 Anti-Caspase 9 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... CASP9(842)
rat ... Casp9(58918)
human, rat
ARR, IHC (p), IP, WB
C9118 Anti-CHIP (N-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... STUB1(10273)
mouse ... Stub1(56424)
rat ... K08D10.11(187155)
human, mouse, rat
WB
HPA001169 Anti-COMT antibody produced in rabbit polyclonal
affinity isolated antibody
human ... COMT(1312)
rat, human
IHC
C6870 Anti-COMT antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... COMT(1312)
mouse ... Comt1(12846)
rat ... Comt(24267)
human, mouse, rat
IP, WB
WH0001312M1 Monoclonal Anti-COMT antibody produced in mouse 1G4-1A1, monoclonal
purified immunoglobulin
human ... COMT(1312)
human
ELISA (i), WB
SAB2500261 Anti-COMT (Internal) antibody produced in goat polyclonal
affinity isolated antibody
human ... COMT(1312)
human
ELISA (i), IHC, WB
C6995 Anti-COMT (N-terminal) antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... COMT(1312)
mouse ... Comt1(12846)
rat ... Comt(24267)
human, rat, mouse
WB
C9616 Anti-Cytochrome c antibody produced in sheep polyclonal
affinity isolated antibody
human ... CYCS(54205)
rat ... Cycs(25309)
human, rat, canine, rabbit
IF, IHC (p), WB
HPA005960 Anti-DBH antibody produced in rabbit polyclonal
affinity isolated antibody
human ... DBH(1621)
human
IHC (p)
HPA017742 Anti-DDC antibody produced in rabbit polyclonal
affinity isolated antibody
human ... DDC(1644)
human, mouse, rat
IF, IHC
GW22156A Anti-DDC (ab1) antibody produced in chicken polyclonal
affinity isolated antibody
human ... DDC(1644)
human
ELISA (i), WB
SAB2500325 Anti-DOPA Decarboxylase antibody produced in goat polyclonal
affinity isolated antibody
human ... DDC(1644)
human
ELISA (i), WB
D0180 Monoclonal Anti-DOPA Decarboxylase (DDC) antibody produced in mouse DDC-109, monoclonal
ascites fluid
human ... DDC(1644)
rat ... Ddc(24311)
canine, rat, human, monkey, bovine, guinea pig, sheep, rabbit
ARR, ELISA (i), ICC, IP, WB
D216 Anti-Dopamine-β-Hydroxylase (C-Terminal) antibody produced in sheep polyclonal
affinity isolated antibody
human ... DBH(1621)
human, bovine, rabbit, monkey
IHC, WB
D0319 Anti-Dorfin (N-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... RNF19A(25897)
mouse ... Rnf19a(30945)
human, mouse, rat (predicted)
WB
H7290 Anti-HtrA2 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... HTRA2(27429)
rat ... Htra2(297376)
human, rat
WB
HPA027366 Anti-HTRA2 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... HTRA2(27429)
human
IHC
WH0027429M2 Monoclonal Anti-HTRA2 antibody produced in mouse 4F10, monoclonal
purified immunoglobulin
human ... HTRA2(27429)
human
ELISA (i), IF, WB
H7165 Anti-HtrA2 (C-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... HTRA2(27429)
mouse ... Htra2(64704)
rat ... Htra2(297376)
human, rat
WB
SAB1300530 Anti-HtrA2 (OMI) (N-term) antibody produced in rabbit polyclonal
saturated ammonium sulfate (SAS) precipitated
human ... HTRA2(27429)
human
ELISA (i)
HPA014293 Anti-LRRK2 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... LRRK2(120892)
human
IF, IHC
L3044 Monoclonal Anti-LRRK2 antibody produced in mouse PROK57, monoclonal
purified immunoglobulin
human ... LRRK2(120892)
mouse ... Lrrk2(66725)
human, mouse
ELISA (i), ICC, WB
WH0120892M1 Monoclonal Anti-LRRK2 antibody produced in mouse 3B2, monoclonal
purified immunoglobulin
human ... LRRK2(120892)
human
ELISA (i), WB
SAB2500604 Anti-LRRK2/PARK8, near C-Terminal antibody produced in goat polyclonal
affinity isolated antibody
human ... LRRK2(120892)
human, bovine
ELISA (i), IHC, WB
L0169 Anti-LRRK2 (C-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... LRRK2(120892)
mouse ... Lrrk2(66725)
rat ... (300160)
human
WB
L9918 Anti-LRRK2 (C-terminal region) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... LRRK2(120892)
mouse ... Lrrk2(66725)
rat ... Lrrk2(300160)
mouse, rat, human
WB
PRS3051 Anti-OMI (ab1) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... HTRA2(27429)
human
ELISA (i), IF, IHC, WB
PRS3319 Anti-OMI (ab2) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... HTRA2(27429)
human
ELISA (i), IF, IHC, WB
M8177 Monoclonal Anti-p38 MAP Kinase, Activated (Diphosphorylated p38) antibody produced in mouse P38-TY, monoclonal
purified immunoglobulin
human ... MAPK14(1432)
mouse ... Mapk14(26416)
rat ... Mapk14(81649)
mouse, rat, human
ARR, ELISA (i), ICC, WB
SAB2500749 Anti-PARK2 antibody produced in goat polyclonal
affinity isolated antibody
human ... PARK2(5071)
human, rat, canine, mouse
ELISA (i), WB
WH0005071M1 Monoclonal Anti-PARK2 antibody produced in mouse 1H4, monoclonal
purified immunoglobulin
human ... PARK2(5071)
human
ELISA (i), WB
HPA004190 Anti-PARK7 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PARK7(11315)
mouse, human, rat
IHC
SAB2101719 Anti-PARK7 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PARK7(11315)
mouse, horse, rabbit, canine, human, pig, chicken, bovine, rat
WB
P9373 Anti-PARK7 (DJ-1) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PARK7(11315)
mouse ... Park7(57320)
rat ... Park7(117287)
human, mouse
WB
SAB2500750 Anti-PARK7/DJ-1 antibody produced in goat polyclonal
affinity isolated antibody
human ... PARK7(11315)
rat, human, mouse
ELISA (i), WB
P5748 Anti-Parkin antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PARK2(5071)
mouse ... Park2(50873)
rat ... Park2(56816)
mouse, rat, human
IHC, WB
P6248 Monoclonal Anti-Parkin antibody produced in mouse PRK8, monoclonal
purified immunoglobulin
human ... PARK2(5071)
mouse ... Park2(50873)
rat ... Park2(56816)
rat, human, mouse, hamster
ARR, WB
SAB4200129 Anti-Phospholipase A2 (iPLA2) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PLA2G6(8398)
mouse ... pla2g6(53357)
rat ... pla2g6(360426)
human, mouse, rat
WB
SAB2500794 Anti-PINK1 antibody produced in goat polyclonal
affinity isolated antibody
human ... PINK1(65018)
rat
ELISA (i), WB
HPA001931 Anti-PINK1 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PINK1(65018)
human
IHC
P0076 Anti-PINK1 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PINK1(65018)
mouse ... Pink1(68943)
rat ... Pink1(298575)
human, rat (predicted), mouse (predicted)
WB
P0075 Anti-PINK1 (N-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PINK1(65018)
human
WB
P0051 Anti-PINK1 (N-terminal region) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... PINK1(65018)
human
WB
WH0025897M1 Monoclonal Anti-RNF19 antibody produced in mouse 4E4, monoclonal
ascites fluid
human ... RNF19A(25897)
human
ELISA (i), WB
HPA023652 Anti-RNF19A antibody produced in rabbit polyclonal
affinity isolated antibody
human ... RNF19A(25897)
human
IHC
SAB2102025 Anti-RNF19A antibody produced in rabbit polyclonal
affinity isolated antibody
human ... RNF19A(25897)
bovine, pig, rat, rabbit, canine, horse, human, mouse, guinea pig
WB
SAB2102253 Anti-SNCA antibody produced in rabbit polyclonal
affinity isolated antibody
human ... SNCA(6622)
canine, bovine, rabbit, human, mouse, rat, pig, horse
WB
WH0006622M1 Monoclonal Anti-SNCA antibody produced in mouse 2E4, monoclonal
purified immunoglobulin
human ... SNCA(6622)
human
ELISA (i), WB
S5946 Anti-Synphilin-1 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... SNCAIP(9627)
mouse ... Sncaip(67847)
rat ... Sncaip(445354)
human
WB
S6071 Anti-Synphilin-1 (C-terminal) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... SNCAIP(9627)
mouse ... Sncaip(67847)
rat ... Sncaip(445354)
human
WB
S3062 Anti-α-Synuclein antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... SNCA(6622)
rat ... Snca(29219)
rat, human
ARR, IHC (p), WB
S5566 Anti-α-Synuclein antibody, Mouse monoclonal Syn211, monoclonal
purified immunoglobulin
human ... SNCA(6622)
zebrafish, human
IHC, IP, WB
SAB1300799 Anti-α-Synuclein (N-term) antibody produced in rabbit polyclonal
saturated ammonium sulfate (SAS) precipitated
human ... ALPHA(6622)
human
ELISA (i), IHC
U5133 Anti-Ubiquitin C-terminal Hydrolase L1 (MA-18) antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... UCHL1(7345)
mouse ... Uchl1(22223)
rat ... Uchl1(29545)
human, mouse, rat
ARR, WB
U5258 Anti-Ubiquitin C-terminal Hydrolase L1 (RA-15) antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... UCHL1(7345)
mouse ... Uchl1(22223)
rat ... Uchl1(29545)
rat, mouse, human
ARR, WB
U5383 Anti-Ubiquitin C-terminal Hydrolase L1 (TS-21) antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... UCHL1(7345)
mouse ... Uchl1(22223)
rat ... Uchl1(29545)
rat, mouse, human
WB
GW22910 Anti-UCHL1 antibody produced in chicken polyclonal
affinity isolated antibody
human ... UCHL1(7345)
human
WB
HPA005993 Anti-UCHL1 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... UCHL1(7345)
mouse, rat, human
IF, IHC
WH0007345M1 Monoclonal Anti-UCHL1 antibody produced in mouse 1B8-4D2, monoclonal
purified immunoglobulin
human ... UCHL1(7345)
human, mouse, rat
ELISA (i), IHC (p), WB