| 141879 | (−)-Lobeline hydrochloride 98% | |  | pricing |
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| N1019 | (−)-Nicotine hemisulfate salt ≥95% (TLC), ~40 % (w/v) in H2O (based on free base) | Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.
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| N5260 | (−)-Nicotine hydrogen tartrate salt ≥98% (TLC), powder | Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.
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| N3876 | (−)-Nicotine ≥99% (GC), liquid | Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.
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| A5656 | (±)-Anabasine ≥90% (TLC), liquid | Tobacco alkaloid; potent nicotinic acetylcholine receptor agonist.
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| E1145 | (±)-Epibatidine dihydrochloride hydrate ≥98% (HPLC), powder | The activity of epibatidine at neuronal and neuromuscular nicotinic acetylcholine receptors was compared with the activity of nicotine and suxamethonium. Activation of ganglionic nicotinic receptors by epibatidine was shown in the guinea-pig ileum (contraction mediated by the cholinergic neurons of the ileum) and in pithed and atropinized rats (rise in blood pressure). Epibatidine also activated nicotinic receptors at the peripheral terminals of afferent C-fibres (rabbit ear) and in the brain (antidiuresis in rats). The agonistic effects of epibatidine were followed by long-lasting receptor desensitization. No antinociceptive effect of epibatidine was seen in rats at a dose free of motor impairment. On muscle end plate nicotinic receptors of the rat diaphragm (not responding to depolarizing agents by contraction), epibatidine was equipotent with suxamethonium in causing neuromuscular inhibition. On an extraocular muscle of the rabbit (responding to depolarizing agents by contraction) epibatidine in vitro and in situ caused a contraction at a 100-fold lower dose than suxamethonium. The Straub tail reaction in mice to epibatidine could be attributed to the sustained stimulation of motor end plate receptors of the "slow contracting" type of muscle fibres by epibatidine. Epibatidine was the most potent agonist on all neuronal and neuromuscular nicotinic receptors examined.
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| M104 | (±)-Muscarine chloride ≥98% | Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.
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| N0267 | (±)-Nicotine ≥98% (TLC), liquid | Prototype nicotinic acetylcholine receptor agonist.
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| N3018 | (±)-Nornicotine ≥99% (TLC), liquid | Nicotinic acetylcholine receptor agonist; active metabolite of nicotine; tobacco alkaloid.
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| M6532 | (+)-Muscarine chloride ~95% (TLC), powder | Prototype muscarinic acetylcholine receptor agonist; active enantiomer.
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| N9765 | (+)-Nicotine (+)-di-p-toluoyltartrate salt ≥98% (TLC), powder | Less active enantiomer of naturally-occurring (−)-nicotine.
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| C008 | (+)-cis-Dioxolane | High affinity muscarinic acetylcholine receptor agonist.
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| D5891 | 1,1-Dimethyl-4-phenylpiperazinium iodide ≥98% (TLC or titration), powder | Nicotinic acetylcholine receptor agonist.
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| A251 | A-85380 dihydrochloride solid | Potent and selective neuronal nicotinic acetylcholine receptor (nAChR) agonist.
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| A6476 | ABT-418 hydrochloride powder, ≥98% (HPLC) | Neuronal nicotinic acetylcholine receptor agonist with cognition enhancing and anxiolytic activities.
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| A2251 | Acetyl-β-methylcholine chloride ≥98% (TLC), powder | Metabolically stable analog of acetylcholine; muscarinic agonist. Its ability to constrict airway smooth muscle is used to assess bronchial reactivity in the laboratory and clinically.
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| A6500 | Acetylcholine bromide ≥99% | Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
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| A6625 | Acetylcholine chloride ≥99% (TLC) | Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
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| 01018 | Acetylcholine chloride BioChemika, ≥99.0% (AT) | Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
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| A7000 | Acetylcholine iodide ≥97% | Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
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| A2394 | Acetylcholine perchlorate | | | pricing |
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| A5626 | Acetylthiocholine chloride ≥99% (TLC), powder | Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.
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| A5751 | Acetylthiocholine iodide ≥98% (TLC), powder | |  | pricing |
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| A140 | Arecaidine propargyl ester hydrobromide solid | Potent muscarinic acetylcholine receptor agonist exhibiting slight selectivity for M2 receptors; inactive at nicotinic receptors.
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| C4382 | Carbamoylcholine chloride ≥98% (titration), crystalline | Non-selective cholinergic agonist that is resistant to the action of cholinesterases; inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes.
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| C5259 | Carbamyl-β-methylcholine chloride ≥99% (TLC), crystalline | |  | pricing |
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| C4740 | Cisapride monohydrate ≥98% (HPLC), solid | 5-HT4 serotonin receptor agonist.
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| C2899 | Cytisine ≥99%, powder | Potent agonist at α3β4 and α7 nicotinic acetylcholine receptors and partial agonist at α4β2 nicotinic acetylcholine receptors.
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| D7938 | DBO-83 solid | Novel nicotinic acetylcholine receptor agonist, structurally related to epibatidine, with antinociceptive properties in rodents.
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| D1260 | Decamethonium bromide crystalline | Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.
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| E152 | Epiboxidine hydrochloride | Potent nicotinic acetylcholine receptor agonist; analog of epibatidine
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| C7041 | McN-A-343 ≥98% (TLC), powder | M1 muscarinic acetylcholine receptor agonist.
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| M8058 | Muscarinic Toxin-2 from Dendroaspis angusticeps venom ≥98% (SDS-PAGE), lyophilized powder | M1 and M4 muscarinic acetylcholine receptor agonist.
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| A6706 | O-Acetyl-L-carnitine hydrochloride ≥99% (titration), powder | Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
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| O9126 | Oxotremorine sesquifumarate salt ≥98% (HPLC), solid | Oxotremorine sesquifumarate salt is a muscarinic acetylcholine receptor agonist with preference for the M2 receptor.
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| O100 | Oxotremorine M solid | Nonselective muscarinic acetylcholine receptor agonist.
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| P6499 | PNU-282987 hydrate solid, ≥98% (HPLC) | Decreased expression of a homomeric alpha7 nicotinic acetylcholine receptor (nAChR) is connected with inability to process sensory information in schizophrenia. PNU-282987 is a novel selective agonist of the alpha7 nAChR that evoked whole-cell currents from cultured rat hippocampal neurons that were sensitive to the selective alpha7 nAChR antagonist methyllycaconitine (MLA) and enhanced GABAergic synaptic activity. The alpha7 nAChR agonist PNU-282987 improves auditory gating and enhances hippocampal oscillatory activity. These results provide further support for the concept that drugs that selectively activate alpha7 nAChRs may offer a novel, potential pharmacotherapy in treatment of schizophrenia.
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| P6503 | Pilocarpine hydrochloride ≥98% (titration), powder | Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.
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| P6628 | Pilocarpine nitrate salt ≥98% (TLC), powder | Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.
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| R131 | RJR-2429 dihydrochloride solid | Nicotinic acetylcholine receptor agonist.
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| V2015 | VU10010 ≥98% (HPLC) | VU10010 is an allosteric M4 agonist.
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| X2754 | Xanomeline L-tartrate hydrate ≥98% (HPLC)  | Xanomeline L-tartate is a M1 muscarinic receptor agonist.
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