AIDS and Viral Research Reagents

AIDS (Acquired Immune Deficiency Syndrome) is the final stage of a disease caused by the Human Immunodeficiency Virus (HIV). HIV/AIDS causes severe damage to the immune system, and a variety of treatments are able to keep symptoms at bay and improve the quality of life. Antiretroviral drugs can stop the virus from multiplying, prevent the progress of the disease, improve T-cell counts, and help the immune system. Viruses are responsible for other infectious diseases like the common cold, influenza, rabies, and measles. Viruses known as oncoviruses contribute to certain forms of cancer. While vaccination provides one treatment option to prevent some viral diseases, another option is the development of antiviral drugs . The first such drug was interferon, produced by immune cells to stimulate other aspects of the immune system. Sigma-Aldrich offers antiviral compounds and other products for research on HIV, AIDS, and other viral diseases.

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SML0089 Abacavir sulfate ≥98% (HPLC)
A4669 Acycloguanosine ≥99% (HPLC), powder
SML0240 Adefovir ≥98% (HPLC)
A9846 2-Aminobenzoyl-Gly(t-butyl)-Asn(methyl)2-Ala-Ser-Ser-Arg-Leu-Tyr(NO2)-Tyr-Arg trifluoroacetate salt >94% (HPLC)
SML0250 anti-3-OS HS peptide trifluoroacetate salt ≥98% (HPLC)
A6486 AS-136A ≥98% (HPLC)
A2169 3′-Azido-3′-deoxythymidine ≥98% (HPLC)
A4810 3′-Azido-2′,3′-dideoxyuridine ≥98% (TLC)
B9647 (E)-5-(2-Bromovinyl)-2′-deoxyuridine
C5874 Cidofovir hydrate ≥98% (HPLC)
D8296 3-Deazaadenosine
PZ0180 Delavirdine mesylate ≥98% (HPLC)
D1413 2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC)
D5782 2′,3′-Dideoxycytidine ≥98% (HPLC)
D0162 2′,3′-Dideoxyinosine ≥98% (HPLC)
SML0536 Efavirenz ≥98% (HPLC) New
F7932 Famciclovir ≥98% (HPLC)
SML0632 Fialuridine ≥98% (HPLC) New
G2536 Ganciclovir ≥99% (HPLC), powder
G6011 Gly-Pro-Gly-Gly ≥97% (HPLC)
H7769 gp120 Fragment 254-274 ≥95% (HPLC)
H6153 gp120 Fragment 421-438 ≥90% (HPLC)
H8909 HBcAg core human ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H7410 HBV core δ antigen (HBcAg) human ~1 mg protein/mL, 95% (SDS-PAGE), recombinant, expressed in E. coli, clone HBV 320
H7035 Hepatitis C virus core antigen−Biotin ~1 mg/mL, >95% (SDS-PAGE), recombinant, expressed in E. coli
H7160 Hepatitis C virus core antigen−Fluorescein ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H9159 Hepatitis C virus core antigen−Rhodamine ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H9284 Hepatitis C virus NS3 antigen 22kDa 0.5-1.4 mg/mL, ≥90% (SDS-PAGE), recombinant, expressed in E. coli
H9534 Hepatitis C virus NS4 antigen ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H7285 Hepatitis C virus NS4 antigen−Biotin ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H9659 Hepatitis C virus NS4 antigen−Fluorescein ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H9784 Hepatitis C virus NS4 antigen−Rhodamine ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli, solution
H9034 Hepatitis C virus core antigen ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
H6387 His-Cys-Lys-Phe-Trp-Trp ≥95% (HPLC)
H9909 HIV-1 env antigen ≥95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged
H4285 HIV-2 env antigen ≥95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged
H0160 HIV-1 gag ≥95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged
H0285 HIV-1 nef >95% (SDS-PAGE), recombinant, expressed in E. coli, Galactosidase-tagged
H5785 HIV Protease Substrate VIII >96% (HPLC)
H5410 HIV Protease Substrate V >98% (HPLC)
H0292 HIV-1 Tat Protein (47-57)
SML0251 anti-HS peptide trifluoroacetate salt ≥98% (HPLC)
I9759 Ile-Pro-Ile ≥97% (HPLC)
SML0189 Indinavir sulfate salt hydrate ≥98% (HPLC)
L1295 Lamivudine ≥98% (HPLC), powder
L6525 Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle amide ≥97% (HPLC)
M9812 α-MAPI ≥95%, solid
PZ0002 Maraviroc ≥98% (HPLC)
M4949 2’-C-Methylcytidine ≥95% (HPLC), powder
D6819 N2-[[5-(Diphenylmethyl)-2-furanyl]carbonyl]-L-Arginine hydrate ≥98% (HPLC), powder
PZ0013 Nelfinavir mesylate hydrate ≥98% (HPLC)
SML0097 Nevirapine
SML0426 NPD4456 ≥98% (HPLC)
N8164 NSC727447 ≥98% (HPLC)
N2790 Nucleozin ≥98% (HPLC), powder
O7385 4-Oxatetradecanoic acid ≥90% (GC)
SML0461 PH-002 ≥98% (HPLC)
A8111 Plasminogen activator inhibitor 1 (PAI-1) human recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
SML0307 Pleconaril ≥98% (HPLC)
SML0561 REDD1 inducer ≥98% (HPLC) New
R9644 Ribavirin antiviral
SML0214 SAMT-247 ≥98% (HPLC)
S5895 Sangivamycin hydrate from Streptomyces rimosus
S8451 Saquinavir mesylate ≥98% (HPLC), powder
S3451 SID 852843 ≥98% (HPLC)
SRP3155 SLIT-2-N human recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SML0293 Telbivudine ≥98% (HPLC)
T7765 Tunicamycin from Streptomyces sp.
V9889 Valacyclovir hydrochloride hydrate ≥98% (HPLC), solid
SML0191 Valganciclovir hydrochloride hydrate ≥98% (HPLC)
SML0492 Zanamivir ≥98% (HPLC) New