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M0896
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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride powder
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Dopaminergic neurotoxin.
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M103
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1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride solid
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Dopaminergic neurotoxin that is more toxic in mice than MPTP.
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850217
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3,4-Dihydroxyphenylacetic acid 98%
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D9378
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3,4-Dihydroxy-D-phenylalanine powder, ≥98%
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DOPA enantiomer that lacks biological activity.
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D9503
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3,4-Dihydroxy-DL-phenylalanine
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Immediate precursor of dopamine; product of tyrosine hydroxylase
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D9628
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3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)
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Natural isomer of the immediate precursor of dopamine; product of tyrosine hydroxylase
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H3132
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3-Hydroxy-4-methoxyphenethylamine hydrochloride
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Dopamine metabolite.
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M4251
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3-Methoxytyramine hydrochloride ≥95.5%, crystalline
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Major metabolite of dopamine; product of catechol O-methyltransferase.
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C156
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D-CPT tartrate >94%, solid
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Binds to the cocaine receptor site on the dopamine transporter and blocks dopamine uptake.
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855456
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D-Tyrosine ReagentPlus®, 99%
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D1507
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L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride solid
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Precursor to L-DOPA that crosses the blood-brain barrier; antiparkinsonian agent.
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T2269
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L-Tyrosine disodium salt hydrate ≥98% (TLC), powder
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T2006
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L-Tyrosine hydrochloride ≥98% (TLC)
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T3754
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L-Tyrosine reagent grade, ≥98% (HPLC)
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A1260
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Amantadine hydrochloride
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Dopamine releaser used to treat Parkinsonism and drug-induced extrapyramidal reactions.
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D4446
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Dopamine D1 Receptor human recombinant, expressed in HEK 293 cells, membrane suspension
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Membranes are suspended in 50 mM TRIS-HCl containing 10 mM MgCl2, 1.5 mM CaCl2, 1mM EDTA, 5 mM KCl, 10% glycerol, (pH 7.4 at 25 °C).
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H1252
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Homovanillic acid Fluorimetric reagent
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Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes
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SML0091
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L-Dopa ethyl ester ≥98% (HPLC)
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L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection.
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D048
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MPP+ iodide ≥98% (HPLC), solid
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MPP+ iodide is an active metabolite of dopaminergic neurotoxin MPTP.
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M3690
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N-Methyl-(R)-salsolinol hydrobromide ≥95% (HPLC), solid
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Endogenous neurotoxin in dopaminergic neurons.
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P138
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PPHT-fluorescein acetate solid
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P0099
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Paliperidone ≥98% (HPLC), solid
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Paliperidone is an atypical antipsychotic; active metabolite of risperidone.
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R0875
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Reserpine
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Inhibits vesicular uptake of catecholamines and serotonin.
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R9157
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Ro 4-1284 ≥98% (HPLC)
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Ro 4-1284 is a reversible VMAT2 inhibitor.
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D204
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S-(+)-O-Desmethylraclopride hydrobromide solid, ≥98% (HPLC)
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S4326
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SB-277011-A hydrochloride hydrate ≥98% (HPLC)
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SB-277011-A is a potent, selective brain-penetrant D3 dopamine receptor antagonist; 80-100x selective for D3 over D2; pKi = 7.95 for hD3 receptor.
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T2952
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Tetrabenazine ≥98% (HPLC), solid
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Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.
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