Sigma-Aldrich
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Antagonists



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D034(−)-Butaclamol hydrochloride solid Dopamine receptor antagonist; less active enantiomer.
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S110(±)-SKF-83566 hydrochloride solid Selective D1 dopamine antagonist; useful in studies involving the radio-brominated derivative.
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S8010(±)-Sulpiride powder D2 dopamine receptor antagonist; antipsychotic.
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D046(+)-Bulbocapnine hydrochloride solid Dopamine receptor antagonist; Water-soluble form of (+)-Bulbocapnine
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D033(+)-Butaclamol hydrochloride solid (+)-Butaclamol is a dopamine receptor antagonist; more active enantiomer.
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S7771(S)-(−)-Sulpiride ≥98% (HPLC) D2 dopamine receptor antagonist; antipsychotic.
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D043(S)-(+)-Apomorphine hydrochloride hydrate solid Dopamine receptor antagonist; inactive as an agonist.
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N3535(S)-Nafadotride tartrate >98% (HPLC), solid D3 Dopamine receptor antagonist.
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P47751-Phenyl-1,3,8-triazaspiro[4.5]decan-4-one ≥90% pricing
A2729Amisulpride ≥98% (HPLC), solid Amisulpride is a highly selective D2/D3 dopamine receptor antagonist and atypical antipsychotic.
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B2060Bromperidol solid Butyrophenone antipsychotic; D2 dopamine and 5-HT2A serotonin antagonist.
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C1671Chlorprothixene hydrochloride D2 dopamine receptor antagonist; blocks a subset of GABAA receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.
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C6305Clozapine Atypical antipsychotic compound. Selective antagonist for D4-dopamine receptor. Antagonist at 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 serotonin receptors.
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D122Domperidone solid, ≥98% (HPLC) Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.
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D1414Droperidol D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.
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F4429FAUC 213 ≥98% (HPLC), solid Highly selective D4 dopamine receptor full antagonist
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F4765Fluphenazine dihydrochloride D1/D2 dopamine receptor antagonist; phenothiazine antipsychotic; H1 histamine receptor antagonist.
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F100Fluspirilene Dopamine receptor antagonist; antipsychotic; calcium channel blocker.
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G0544GR 103691 >98% (HPLC), solid D3 dopamine receptor antagonist.
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G9168GR 218231 >98% (HPLC), solid Selective D3 dopamine receptor antagonist.
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H3041Halopemide ≥98% (HPLC) Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay.
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H1512Haloperidol powder Butyrophenone antipsychotic; D2, D3, and D4 dopamine receptor antagonist.
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L135L-741,626 ≥98% (HPLC), solid Selective D2 dopamine receptor antagonist.
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L131L-745,870 hydrochloride solid Selective D4 dopamine receptor antagonist.
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L133L-750,667 trihydrochloride solid Selective D4 dopamine receptor antagonist.
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L8401LE 300 solid Potent, selective D1 dopamine receptor antagonist.
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L106Loxapine succinate salt solid D2/D4 dopamine receptor antagonist; 5-HT2A/2B, 5-H7 serotonin receptor antagonist; dibenzoxazepine antipsychotic agent.
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M4068Mesoridazine benzenesulfonate ≥98% (HPLC), solid Mesoridazine benzenesulfonate is a D2 dopamine receptor antagonist; antipsychotic.
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M0763Metoclopramide hydrochloride solid D2 antagonist; 5-HT3 antagonist; antipsychotic; anti-emetic
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M1818Molindone hydrochloride ≥98% (HPLC), solid D2 dopamine receptor antagonist; MAO inhibitor.
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N140N-(p-Isothiocyanatophenethyl)spiperone hydrochloride Selective irreversible D2 dopamine receptor antagonist.
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S128N-Methylspiperone hydrochloride solid D2 dopamine receptor antagonist.
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O111Octoclothepin maleate salt solid D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist.
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P6402Perphenazine D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro.
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P1793Pimozide D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor; Ca2+ channel antagonist; antipsychotic
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P3246Pipamperone dihydrochloride ~99% (HPLC), powder D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist; antipsychotic.
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P9178Prochlorperazine dimaleate salt Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic
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P3847Prochlorperazine edisylate meets USP testing specifications Phenothiazine antipsychotic; D2 antagonist; antispasmodic
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P6656Promazine hydrochloride D2 dopamine receptor antagonist; phenothiazine antipsychotic.
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P7780Propionylpromazine hydrochloride Phenothiazine antipsychotic; D2 dopamine receptor antagonist
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S159R(−)-SCH-12679 maleate salt solid D1 dopamine receptor antagonist
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D054R(+)-SCH-23390 hydrochloride ≥98% (HPLC), solid R(+)-SCH-23390 hydrochloride is a selective D1 dopamine receptor antagonist.
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D206S(−)-DS 121 hydrochloride solid Dopamine autoreceptor antagonist with some selectivity for the D3 dopamine receptor.
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R121S(−)-Raclopride (+)-tartrate salt >97%, solid Selective D2 dopamine receptor antagonist.
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D041S(+)-Propylnorapomorphine hydrochloride solid Limbic-selective dopamine antagonist.
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E101S-(-)-Eticlopride hydrochloride ≥98% (HPLC), solid Potent and selective D2 dopamine receptor antagonist.
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S1441ST-148 solid ST-148 is a D2 dopamine receptor antagonist. Compared to haloperidol and (S)-nafodotride, ST-148 exhibits improved selectivity for hD2L receptors. ST-148 has a pKi = 7.85 at hD2L receptors.
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S7395Spiperone solid Selective D2 dopamine receptor antagonist; α1B-adrenoceptor antagonist; mixed 5-HT2A/5-HT1 serotonin receptor antagonist; antipsychotic.
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T4699Tetrahydroberberine ≥99% (HPLC), solid Dopamine receptor antagonist; nicotinic acetylcholine receptor (α4β2, α4β4, α7, α1β, 1γδ) modulator
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T9025Thioridazine hydrochloride ≥99% D2 dopamine receptor antagonist; phenothazine antipsychotic with reduced extrapyramidal side effects; Ca2+ channel blocker.
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T0410Tiapride hydrochloride D2 and D3 dopamine receptor antagonist; antipsychotic.
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T103Trifluperidol hydrochloride Dopamine receptor antagonist; antipsychotic.
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T2896Triflupromazine hydrochloride D2 dopamine antagonist; phenothiazine antipsychotic.
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U115U-101958 maleate salt solid Selective D4 dopamine receptor antagonist.
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U116U-99194 maleate salt ≥98% (HPLC), solid U-99194 is a putative D3 antagonist with a 30-fold preference for the dopamine D3 vs. D2 receptor.
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F114cis-(Z)-Flupenthixol dihydrochloride ≥98% (HPLC), solid Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
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