Inositol Phosphates

Inositol phosphates are important intracellular second messengers in eukaryotic cells. Inositol, a cyclic molecule with six hydroxyl groups, forms the hydrophobic head group of membrane inositol phospholipids. The actions of lipid kinases and phosphatases on the inositol ring of inositol phospholipids generate a variety of phosphoinositol phospholipids. As a result of upstream signaling events, specific phospholipases are activated, cleave phosphoinositol phospholipids, and release intracellular inositol phosphate second messenger molecules.
The most studied inositol phosphate second messenger is inositol 1,4,5-trisphosphate (IP₃). IP₃ is released from phosphatidylinositol 4,5-bisphosphate (PIP₂) by the action of phospholipase C-β and is responsible for the release of calcium ions from intracellular stores in the endoplasmic reticulum.

Product #	Description	Add to Cart
P4240	1,2-Dipalmitoylphosphatidylinositol 3,4,5-trisphosphate hexasodium salt ≥98%	pricing

P6990	1,2-Dipalmitoylphosphatidylinositol 3,4-diphosphate tetrasodium salt ≥98%, solid	pricing

P7115	1,2-Dipalmitoylphosphatidylinositol 4,5-diphosphate ≥98%, solid	pricing

P1652	D-α-Phosphatidylcholine, dipalmitoyl ≥99%	pricing

I8636	D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt ~95%	pricing

I0143	D-myo-Inositol 1,3,4,5-tetrakis(phosphate) potassium salt	pricing

I131	D-myo-Inositol 1,3,4,5-tetrakis(phosphate) potassium salt	pricing

I9766	D-myo-Inositol 1,4,5-tris-phosphate trisodium salt	pricing

I0510	D-myo-Inositol 1,4-bisphosphate potassium salt from bovine brain, ≥98% (TLC)	pricing

I0146	D-myo-Inositol 2,4,5-tris-phosphate ammonium sodium salt	pricing

I3264	D-myo-Inositol 4,5-bisphosphate ammonium salt	pricing

P9953	L-α-Phosphatidyl-D-myo-inositol 3,4,5-triphosphate, dioctanoyl	pricing

P4725	L-α-Phosphatidyl-D-myo-inositol 3,4-diphosphate, dioctanoyl	pricing

P5713	L-α-Phosphatidyl-D-myo-inositol 3,5-diphosphate, dipalmitoyl	pricing

P5578	L-α-Phosphatidyl-D-myo-inositol 3-monophosphate, dioctanoyl	pricing

P3953	L-α-Phosphatidyl-D-myo-inositol 3-monophosphate, dipalmitoyl	pricing

P3584	L-α-Phosphatidyl-D-myo-inositol 4,5-diphosphate, dioctanoyl	pricing

P9943	L-α-Phosphatidyl-D-myo-inositol 4-monophosphate, dioctanoyl	pricing

P7686	L-α-Phosphatidyl-D-myo-inositol 4-monophosphate, dipalmitoyl ammonium salt	pricing

P0686	L-α-Phosphatidyl-D-myo-inositol 5-monophosphate, dioctanoyl	pricing

P1168	L-α-Phosphatidyl-D-myo-inositol 5-monophosphate, dipalmitoyl	pricing

P9763	L-α-Phosphatidylinositol 4,5-diphosphate sodium salt from bovine brain ≥98% (TLC)	pricing

P1368	L-α-Phosphatidylinositol dipalmitoyl ammonium salt ≥98% (TLC)	pricing

I7012	D-myo-Inositol 1,4,5-trisphosphate potassium salt synthetic	pricing

L9908	LY-294,002 hydrochloride solid, ≥98% (HPLC)	pricing

P8615	Phosphoinositide 3-kinase p110γ human >95% (SDS-PAGE), recombinant, expressed in insect cells, buffered aqueous glycerol solution	pricing

P6023	Phosphoinositides sodium salt from bovine brain	pricing

Q0125	Quercetin dihydrate ≥98% (HPLC), powder	pricing

Q4951	Quercetin ≥98% (HPLC), solid	pricing

W3144	Wortmannin, Ready Made Solution from Penicillium funiculosum, >95% (HPLC)	pricing

W1628	Wortmannin from Penicillium funiculosum, ≥98% (HPLC and TLC)	pricing

I9261	myo-Inositol 1,3,4,5,6-pentakisphosphate ≥95%	pricing

I5125	myo-Inositol ≥99%	pricing

I7508	myo-Inositol cell culture tested, insect cell culture tested	pricing

I8132	scyllo-Inositol ≥98%	pricing

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