Scorpion

Product #

Description

Biochem/physiol Actions

Add to Cart

C7802 Charybdotoxin ≥90% (HPLC) High (BK) or intermediate (IK1) conductance calcium-activated and voltage-gated (Kv1.3) channel blocker.
Potent and selective inhibitor of the Ca2+-activated K+ channel present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells.
C5856 Charybdotoxin, recombinant from Leiurus quinquestriatus hebraeus recombinant, expressed in E. coli, lyophilized powder Exhibits the same activity as the natural form of the toxin
I5904 Iberiotoxin, recombinant from Mesobuthus tamulus ≥98% (HPLC), recombinant, expressed in E. coli Exhibits the same activity as the natural form of the toxin
The single chain peptide iberiotoxin (IbTX) is a selective and reversible inhibitor of high-conductance calcium-activated potassium channels (PK,Ca). It occurs naturally in the venom of the scorpion Buthus tamulus. IbTX also modulates the binding of charybdotoxin (CbTX) to smooth muscle sarcolemmal membranes in a non-competitive manner. IbTX is similar in size to CbTX and shares considerable sequence homology with CbTX. However, IbTX differs in its overall charge in having one fewer basic and four more acidic residues than CbTX.
I148 Imperatoxin A >88%, lyophilized powder Selective skeletal-type ryanodine sensitive intracellular Ca2+ channel activator found in the scorpion Pandinus
M8437 Margatoxin ≥99%, recombinant, expressed in E. coli Voltage-gated (Kv1.3) potassium channel blocker.
M8278 Margatoxin ≥90% (HPLC) Specific K(V)1.3 channel voltage-dependent K+ channel blocker
P222 Pandinotoxin-Kα >99%, powder Pandinotoxin (PiTX) –Kα along with PiTX-Kβ and PiTXγ plays a vital role in blocking voltage-gated K+ channels.
V9752 Scorpion venom from Centruroides sculpturatus  
V5251 Scorpion venom from Leiurus quinquestriatus (north Africa)  
V1752 Scorpion venom from Tityus serrulatus