Arrays & Interaction Profiling

Panorama® Antibody Array – Signal Transduction

The Panorama Signal Transduction Functional Protein Array eases the process of identifying cellular response to external signals. Based on a proprietary tagging technology that ensures only functional proteins are immobilized, our comprehensive analysis system enables high throughput analysis against 259 human cell signaling proteins.

  • Full-length representation of 259 human signaling proteins involved in cell proliferation, cell differentiation and cell death
  • Probe with DNA, proteins, kinases or small molecules
  • Complete analysis system including buffers, techware, and software

Functional Array Technology

Slide Analysis Software (84.2 Kb GAL file)

Slide Analysis Template (4.71 Mb Excel file)

Signal Transduction Array Content

Order Information

Product No. Description Technical Bulleti
HPFM4 Panorama® Human Protein Array-Signal Transduction

Kit Contents

  • Signal Transduction Protein
    Array - 2 ea
  • BCR-peptide - Cy™5
  • Monoclonal Anti-c-Myc-Cy™3 Conjugate
  • Cover slips
  • quadiPERM® Vessel
  • 50 mL Conicol - 2 ea
  • Pap Jar - 4 ea
  • Assay Buffer
  • Functional Buffer
  • CHAPS
  • BSA
  • 1M DTT
  • Signal Transduction CD (GAL file and analysis spreadsheet)

Signal Transduction Array Content

Symbol Gene Name Entrez Gene ID
ABI1 Ab1 interactor 1 10006
ACVR1 activin A receptor, type I 90
ADD1 adducin 1 (alpha) 118
ADRBK2 adrenergic, beta, receptor kinase 2 157
AKT1 v-akt murine thymoma viral oncogene homolog 1 207
AMD1 adenosylmethionine decarboxylase 1 262
ANXA1 annexin A1 301
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 328
ARAF1 v-raf murine sarcoma 3611 viral oncogene homolog 1 369
ARHA ras homolog gene family, member A 387
ARRB1 arrestin, beta 1, transcript variant 1 408
ATF3 activating transcription factor 3 467
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 468
BAD BCL2-antagonist of cell death 572
BCL10 B cell lymphoma/leukemia 10 8915
BCL2A1 BCL2-related protein A1 597
BDNF brain-derived neurotrophic factor, transcript variant 5 627
BIRC2 baculoviral IAP repeat-containing 2 329
BIRC3 baculoviral IAP repeat-containing protein 3 330
BIRC5 baculoviral IAP repeat-containing 5 (survivin) 332
BLK B lymphoid tyrosine kinase 640
BMP7 bone morphogenetic protein 7 (osteogenic protein 1) 655
BMPR1A bone morphogenetic protein receptor, type IA 657
BMX BMX non-receptor tyrosine kinase 660
BRD8 bromodomain containing 8 10902
BTRC beta-transducin repeat containing, transcript variant 1 8945
BUB1B BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) 701
CA1 carbonic anhydrase I 759
CALM1 calmodulin 1 (phosphorylase kinase, delta) 801
CALM2 calmodulin 2 (phosphorylase kinase, delta) 805
CALM3 calmodulin 3 (phosphorylase kinase, delta) 808
CAMK2B calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 816
CAMK2G calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 818
CAMK4 calcium/calmodulin-dependent protein kinase IV 814
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 10645
CASP3 caspase 3, apoptosis-related cysteine protease 836
CASP9 caspase 9, apoptosis-related cysteine protease 842
CCNB1 cyclin B1 891
CCND1 cyclin D1 (PRAD1: parathyroid adenomatosis 1) 595
CCND2 cyclin D2 894
CCNH cyclin H 902
CDC2 cell division cycle 2, G1 to S and G2 to M 983
CDC20 CDC20 cell division cycle 20 homolog (S. cerevisiae) 991
CDC25A cell division cycle 25A 993
CDC25B cell division cycle 25B 994
CDC25C cell division cycle 25C 995
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 998
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1026
CDKN2B cyclin-dependent kinase inhibitor 2B 1030
CDKN2C cyclin-dependent kinase inhibitor 2C 1031
CDKN2D cyclin-dependent kinase inhibitor 2D 1032
CGEF2 cAMP-regulated guanine nucleotide exchange factor II 11069
CHN1 chimerin (chimaerin) 1 1123
CISH cytokine inducible SH2-containing protein 1154
CNN1 calponin 1, basic, smooth muscle 1264
CREB1 cAMP responsive element binding protein 1 1385
CSEN calsenilin, presenilin binding protein, EF hand transcription factor 30818
CSNK1D casein kinase 1 1453
CSNK1G1 BC017236, casein kinase 1 53944
CSNK1G2 casein kinase 1 1455
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1457
CSNK2A2 casein kinase 2, alpha prime polypeptide 1459
CSTB cystatin B (stefin B) 1476
CTNNB1 Beta-catenin 1499
DDB1 damage-specific DNA binding protein 1 1642
DDIT3 DNA-damage-inducible 1649
DNAJB1 DnaJ (Hsp40) homolog, subfamily B 3337
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1810
DSCR1 Down syndrome critical region gene 1 1827
DUSP6 dual specificity phosphatase 6 1848
DVL2 dishevelled, dsh homolog 2 (Drosophila) 1856
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1915
EFS embryonal Fyn-associated substrate 10278
EGR2 early growth response 2 (Krox-20 homolog, Drosophila) 1959
EIF4E eukaryotic translation initiation factor 4E 1977
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1978
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004
EMS1 ems1 sequence (mammary tumor and squamous cell carcinoma-associated) 2017
ENO1 enolase 1 2023
ENO2 enolase 2 2026
EPS15 epidermal growth factor receptor substrate 15 2060
ERG transcriptional regulator ERG 2078
ESR2 estrogen receptor 2 (ER beta) 2100
ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2 2114
EXT1 exostoses (multiple) 1 2131
EXT2 exostoses (multiple) 2 2132
EZH2 enhancer of zeste homolog 2 (Drosophila) 2146
FADD Fas (TNFRSF6)-associated via death domain 8722
FEN1 flap structure-specific endonuclease 1 2237
FES feline sarcoma oncogene 2242
FGF1 fibroblast growth factor 1 (acidic) 2246
FGF13 fibroblast growth factor 13 2258
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2346
FRK fyn-related kinase 2444
FYN FYN oncogene related to SRC, FGR, YES 2534
GADD45G growth arrest and DNA-damage-inducible 10912
GATA3 GATA binding protein 3 2625
GCLC glutamate-cysteine ligase, catalytic subunit 2729
GEM GTP binding protein overexpressed in skeletal muscle 2669
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2769
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2771
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 2773
GNA01 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide O 2775
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2781
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 2782
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 2784
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2791
GNG2 guanine nucleotide binding protein (G protein), gamma 2 54331
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2785
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2786
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 2792
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2793
GOLGA5 golgi autoantigen, golgin subfamily a 9950
GPRK6 G protein-coupled receptor kinase 6 2870
GRB10 growth factor receptor-bound protein 10 2887
GRB2 growth factor receptor-bound protein 2 2885
GSK3B glycogen synthase kinase 3 beta 2932
HBG1 hemoglobin, gamma A 3047
HCLS1 hematopoietic cell-specific Lyn substrate 1 3059
HIF1A hypoxia-inducible factor 1, alpha subunit 3091
HIF3A hypoxia inducible factor 3, alpha subunit 64344
HIST1H4I histone 1, H4i 8294
HK1 hexokinase 1 3098
HMGB2 high-mobility group box 2 3148
HPRT1 hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) 3251
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 3265
HSPA1A heat shock 70kDa protein 1A 3303
HSPCA heat shock 90kDa protein 1, alpha 3320
HUS1 HUS1 checkpoint homolog 3364
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 3397
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3398
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells 3551
IL18 interleukin 18 3606
ILK integrin-linked kinase 3611
IMPDH1 IMP (inosine monophosphate) dehydrogenase 1 3614
INDO indoleamine-pyrrole 2,3 dioxygenase 3620
INHBA inhibin, beta A (activin A, activin AB alpha polypeptide) 3624
IRF5 interferon regulatory factor 5 3663
ISG20 interferon stimulated gene 20kDa 3669
JIK STE20-like kinase 51347
KRAS2 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog 3845
LCK lymphocyte-specific protein tyrosine kinase 3932
LIMK2 LIM domain kinase 2 3985
MADH2 MAD, mothers against decapentaplegic homolog 2 4087
MADH4 MAD, mothers against decapentaplegic homolog 4 4089
MADH4 MAD, mothers against decapentaplegic homolog 5 4090
MADH9 MAD, mothers against decapentaplegic homolog 9 4093
MAP2K3 mitogen-activated protein kinase kinase 3 5606
MAP2K5 mitogen-activated protein kinase kinase 5 5607
MAP2K6 mitogen-activated protein kinase kinase 6 5608
MAP3K6 mitogen-activated protein kinase kinase kinase 6 9064
MAP3K7 mitogen-activated protein kinase kinase kinase 7 6885
MAPK1 mitogen-activated protein kinase 1 5594
MAPK11 mitogen-activated protein kinase 11 5600
MAPK13 mitogen-activated protein kinase 13 5603
MAPK14 mitogen-activated protein kinase 14 1432
MAPK6 mitogen-activated protein kinase 6 5597
MAPK7 mitogen-activated protein kinase 7 5598
MAPK9 mitogen-activated protein kinase 9 5601
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 7867
MATK megakaryocyte-associated tyrosine kinase 4145
MAX MAX protein 4149
MCM5 MCM5 minichromosome maintenance deficient 5 4174
MEF2A MADS box transcription enhancer factor 2, polypeptide A 4205
MEF2C MADS box transcription enhancer factor 2, polypeptide C 4208
MIF macrophage migration inhibitory factor 4282
MKNK1 MAP kinase-interacting serine/threonine kinase 1 8569
MMP2 matrix metalloproteinase 2 4313
MTCP1 mature T-cell proliferation 1 4515
MYBL2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 4605
MYD88 myeloid differentiation primary response gene (88) 4615
NCK1 NCK adaptor protein 1 4690
NCOA4 nuclear receptor coactivator 4 8031
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor 4792
NR1I2 nuclear receptor subfamily 1, group I, member 2 8856
NR3C1 nuclear receptor subfamily 3, group C, member 1 2908
NR4A1 nuclear receptor subfamily 4, group A, member 1 3164
NR4A2 nuclear receptor subfamily 4, group A, member 2 4929
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 318
PAK4 p21(CDKN1A)-activated kinase 4 10298
PDE4A phosphodiesterase 4A, cAMP-specific 5141
PDK1 pyruvate dehydrogenase kinase, isoenzyme 1 5163
PIK3R1 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 5295
PLD2 phospholipase D2 5338
PPARG peroxisome proliferative activated receptor 5468
PPM1A protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha 5494
PPP2R2B protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta 5521
PPP2R2C protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma 5522
PPP2R5A protein phosphatase 2, regulatory subunit B (B56), alpha 5525
PPP2R5C protein phosphatase 2, regulatory subunit B (B56), gamma 5527
PRDM4 PR domain containing 4 11108
PRKACB protein kinase, cAMP-dependent, catalytic, beta 5567
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 5573
PRKCB1 protein kinase C, beta 1 5579
PRKCH protein kinase C, eta 5583
PRKCI protein kinase C, iota 5584
PRKCN protein kinase C, nu 23683
PRKCZ protein kinase C, zeta 5590
PRKD2 protein kinase D2 25865
PTK2 PTK2 protein tyrosine kinase 2 5747
PTPN1 protein tyrosine phosphatase, non-receptor type 1 5770
PTPN11 protein tyrosine phosphatase, non-receptor type 11 5781
PXK PX domain containing serine/threonine kinase 54899
RAC1 ras-related C3 botulinum toxin substrate 1 5879
RAC2 ras-related C3 botulinum toxin substrate 2 5880
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 5894
RARA retinoic acid receptor 5914
RET ret proto-oncogene 5979
RHOH ras homolog gene family, member H 399
RIPK2 receptor-interacting serine-threonine kinase 2 8767
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 6195
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 6196
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 9252
RRAS related RAS viral (r-ras) oncogene homolog 6237
RRAS2 related RAS viral (r-ras) oncogene homolog 2 22800
SAV1 salvador homolog 1 77085
SGKL serum/glucocorticoid regulated kinase-like 23678
SH2B SH2-B homolog 25970
SLA Src-like-adaptor 6503
SNK serum-inducible kinase 10769
SOCS2 suppressor of cytokine signaling 2 8835
SOCS4 suppressor of cytokine signaling 4 9306
SOCS5 suppressor of cytokine signaling 5 9655
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 6678
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 6714
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 8027
STAT1 signal transducer and activator of transcription 1, 91kDa 6772
STAT3 signal transducer and activator of transcription 3 6774
STAT4 signal transducer and activator of transcription 4 6775
STAT5A signal transducer and activator of transcription 5A 6776
STK17B serine/threonine kinase 17b (apoptosis-inducing) 9262
STK22C serine/threonine kinase 22C (spermiogenesis associated) 81629
STK24 serine/threonine kinase 24 8428
STK25 serine/threonine kinase 25 10494
STK3 serine/threonine kinase 3 6788
STK38 serine/threonine kinase 38 11329
STK38L serine/threonine kinase 38 like 23012
STK6 serine/threonine kinase 6 6790
STMN1 stathmin 1/oncoprotein 18 3925
SYK spleen tyrosine kinase 6850
TBK1 TANK-binding kinase 1 29110
TBL1X transducin (beta)-like 1X-linked 6907
TEK TEK tyrosine kinase, endothelial 7010
TFG TRK-fused gene 10342
TLK1 tousled-like kinase 1 9874
TNFRSF6 tumor necrosis factor receptor superfamily 355
TOLLIP toll interacting protein 54472
TRAF2 TNF receptor-associated factor 2 7186
TRAF4 TNF receptor-associated factor 4 9618
TRAF5 TNF receptor-associated factor 5 7188
TRAF6 TNF receptor-associated factor 6 7189
TRAP100 thyroid hormone receptor-associated protein 9862
TRAP25 TRAP/Mediator complex component 90390
TTRAP TRAF and TNF receptor associated protein 51567
VAV1 vav 1 oncogene 7409
VDRIP vitamin D receptor interacting protein 29079
VEGFB vascular endothelial growth factor B 7423
ZAK sterile alpha motif and leucine zipper containing kinase AZK 51776
ZAP70 zeta-chain (TCR) associated protein kinase 7535

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