Cytokines as adjuvants

While cytokine adjuvant use has been limited due to toxicity and immunogenicity, they do have potential in DNA vaccines coexpressed with an antigen. Cytokine adjuvant use has been used t oaffect magnitude and direction of immune responses in animal models. Many cytokines, such as IL-12 stimulate macrophage activation via TLR signaling.

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SRP3002 4-1BBL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3006 AITRL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3189 APRIL from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3008 APRIL human recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP3009 BAFF Receptor human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP3010 BCMA human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3036 Fas Ligand human recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP3037 FAS Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
F3422 Flt-3/Flk-2 ligand human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)
G8160 Granulocyte Colony-Stimulating Factor from mouse G-CSF, recombinant, expressed in E. coli, suitable for cell culture
G0282 Granulocyte-Macrophage Colony-Stimulating Factor from mouse GM-CSF, from mouse, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
G0792 Granulocyte-Macrophage Colony-Stimulating Factor from rat GM-CSF, recombinant, expressed in E. coli
G5035 Granulocyte-Macrophage Colony-Stimulating Factor human GM-CSF, recombinant, expressed in E. coli, suitable for cell culture
SRP3056 HVEM-Fc human recombinant, expressed in Hi-5 Insect cells, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3242 IL-2 from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3085 IL-2 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3213 IL-9 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3245 IL-9 from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3099 IL-9 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
I8657 Interferon α from rat ≥95%, recombinant, expressed in bacteria, lyophilized powder, cell culture tested
57600 Interleukin-2 human ≥98.0% (GE), recombinant, expressed in E. coli, ~10000 U/mL
I5273 Interleukin-5 human recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, cell culture tested
I3268 Interleukin-6 human IL-6, from human (osteosarcoma cells), solution, suitable for cell culture
I1395 Interleukin-6 human IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
I5896 Interleukin-7 human ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
I1645 Interleukin-8 human ≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
I9276 Interleukin-10 human ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
I2276 Interleukin-12 human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
I0531 Interleukin-18 from rat >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
SRP3217 LIGHT from mouse recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), cell culture tested
M6518 Macrophage Colony-Stimulating Factor human M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
M6417 Macrophage Inflammatory Protein-1β human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
SRP3133 OX40 Ligand human recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), cell culture tested
R6267 RANTES human ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
SRP3001 4-1BB Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3161 sRANKL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3254 sRank Ligand from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3160 sRank Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3162 sTNF-receptor Type I human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3163 sTNF-receptor Type II human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3164 sTRAIL Receptor-1 (DR4) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3165 sTRAIL Receptor-2 (DR5) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3166 TACI human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3175 TL-1A human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3176 TLR-3 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP3177 TNF-α human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3237 TRAIL from mouse recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
T6674 Tumor Necrosis Factor-α human TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
SRP3180 TWEAK Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested