Cytokines as adjuvants

While cytokine adjuvant use has been limited due to toxicity and immunogenicity, they do have potential in DNA vaccines coexpressed with an antigen. Cytokine adjuvant use has been used t oaffect magnitude and direction of immune responses in animal models. Many cytokines, such as IL-12 stimulate macrophage activation via TLR signaling.

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SRP3002 4-1BBL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3006 AITRL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3189 APRIL from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3008 APRIL human recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
    • SRP3009 BAFF Receptor human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
    • SRP3010 BCMA human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3036 Fas Ligand human recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
    • SRP3037 FAS Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • F3422 Flt-3/Flk-2 ligand human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)
    • G8160 Granulocyte Colony-Stimulating Factor from mouse recombinant, expressed in E. coli, suitable for cell culture
    • G0282 Granulocyte-Macrophage Colony-Stimulating Factor from mouse from mouse, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
    • G0792 Granulocyte-Macrophage Colony-Stimulating Factor from rat from rat, recombinant, expressed in E. coli
    • G5035 Granulocyte-Macrophage Colony-Stimulating Factor human recombinant, expressed in E. coli, suitable for cell culture
    • SRP3056 HVEM-Fc human recombinant, expressed in Hi-5 Insect cells, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3242 IL-2 from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3085 IL-2 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3213 IL-9 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3245 IL-9 from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3099 IL-9 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • I8657 Interferon α from rat ≥95%, recombinant, expressed in bacteria, lyophilized powder, cell culture tested
    • 57600 Interleukin-2 human ≥98.0% (GE), recombinant, expressed in E. coli, ~10000 U/mL
    • I5273 Interleukin-5 human recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, cell culture tested
    • I3268 Interleukin-6 human from human (osteosarcoma cells), solution, suitable for cell culture
    • I1395 Interleukin-6 human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
    • I5896 Interleukin-7 human ≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
    • I1645 Interleukin-8 human ≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
    • I9276 Interleukin-10 human ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
    • I2276 Interleukin-12 human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
    • I0531 Interleukin-18 from rat >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
    • SRP3217 LIGHT from mouse recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), cell culture tested
    • M6518 Macrophage Colony-Stimulating Factor human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
    • M6292 Macrophage Inflammatory Protein-1α human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
    • M6417 Macrophage Inflammatory Protein-1β human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested
    • SRP3133 OX40 Ligand human recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), cell culture tested
    • R6267 RANTES human ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
    • SRP3001 4-1BB Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3161 sRANKL human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3254 sRank Ligand from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3160 sRank Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3162 sTNF-receptor Type I human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3163 sTNF-receptor Type II human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3164 sTRAIL Receptor-1 (DR4) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3165 sTRAIL Receptor-2 (DR5) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3166 TACI human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3175 TL-1A human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3176 TLR-3 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
    • SRP3177 TNF-α human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
    • SRP3237 TRAIL from mouse recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
    • T6674 Tumor Necrosis Factor-α human powder, recombinant, expressed in E. coli, suitable for cell culture
    • SRP3180 TWEAK Receptor human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested