CHOZN® Cells and Reagents

The CHOZN® platform is a Chinese Hamster Ovary (CHO) mammalian expression system for the fast and easy selection and scale up of clones producing high levels of recombinant proteins. Key to the CHOZN® Platform is the development of the CHOZN® ZFN Modified GS-/- CHO cell line that eliminates the endogenous glutamine synthetase (GS). The platform also includes an optimized set of cGMP produced chemically defined (CD) growth and production medium and feeds that have been developed to maximize the growth and production of recombinant proteins from producing clones.

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CHODHFR CHOZN® DHFR-/- ZFN-Modified CHO Cell Line
CHOGS CHOZN® GS-/- ZFN-modified CHO cell line
ZFNDHFR CompoZr® Knockout ZFN Kit- CHO DHFR dihydrofolate reductase
ZFNGS CompoZr® Knockout ZFN Kit- CHO GS glutamine synthetase
C6366 EX-CELL® CHO Cloning Medium Animal-component free, without L-glutamine, liquid, sterile-filtered, suitable for cell culture