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Neurotrophic Factors

Neurotrophic factors are agents that are important for survival, growth, or differentiation of discrete neuronal populations. Based on amino acid sequence homologies of cytokines and receptors and the similarities in cytokine-receptor binding characteristics, neurotrophic factors can be divided into three general families.
1. Neurotrophin Family
2. CNTF Family
3. GDNF Family

There are a few other Neurotrophic Factors that typically do not align with the families listed above.

Click here for our entire offering of Growth Factors & Cytokines.
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Explore our high quality recombinant Neurotrophic Factors for your research needs.

CNTF Family - includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF) and interleukin-6 (IL-6)

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C3835 Ciliary Neurotrophic Factor from rat recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE), carrier free
C3710 Ciliary Neurotrophic Factor human CNTF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
SRP3330 IL-6 from mouse Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP4145 IL-6 from rat recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)
SRP3096 IL-6 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
I0406 Interleukin-6 from rat IL-6, recombinant, expressed in E. coli, buffered aqueous solution, cell culture tested
SRP6197 IL-6Rα human recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE)
SRP3097 IL-6 Receptor human recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
I9646 Interleukin-6 from mouse IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free
I3268 Interleukin-6 human IL-6, from human (osteosarcoma cells), solution, suitable for cell culture
I1395 Interleukin-6 human IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
H7416 Interleukin-6 human IL-6, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
SCU0001 Interleukin-6 human recombinant, expressed in HEK 293 cells, suitable for cell culture
I2786 Interleukin-6 human IL-6, recombinant, expressed in E. coli, Animal Component Free
11138600001 Interleukin-6, human (hIL-6) recombinant (E. coli)
SRP9001 Leukemia Inhibitory Factor human, recombinant, expressed in HEK 293 cells
SRP3235 SF-20 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested

GDNF Family - includes glial cell line derived neurotrophic factor (GDNF), neurturin (NTN), artemin (ART) and persephin (PSP)

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SRP4515 Artemin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
SRP3200 GDNF from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3239 GDNF from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3309 GDNF human recombinant, expressed in E. coli, Animal-component free, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP6474 GFRA1/GDNFRA human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP6475 GFRA2/GDNFRB human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
G1401 Glial Cell Line-derived Neurotrophic Factor from rat recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE)
G1777 Glial Cell Line-derived Neurotrophic Factor human recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE)
SRP3124 Neurturin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3230 Persephin from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3141 Persephin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
P5333 Pleiotrophin human ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested

Neurotrophin family - includes nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrohin-3 (NT-3) and neurotrohin-4 (NT-4)

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SRP3014 BDNF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3018 Beta -NGF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3015 Beta NGF human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
B3795 Brain-derived neurotrophic factor human BDNF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
N8133 Nerve Growth Factor from Vipera lebetina venom NGF, lyophilized powder, suitable for cell culture
N0513 Nerve Growth Factor-7S from murine submaxillary gland NGF-7S, lyophilized powder, suitable for cell culture
N6009 Nerve Growth Factor-2.5S from murine submaxillary gland NGF-2.5S, lyophilized powder, suitable for cell culture
H9666 Nerve Growth Factor β Human NGF-β, recombinant, expressed in HEK 293 cells, HumanKine, suitable for cell culture
N5415 Nerve Growth Factor-ß human recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
N1905 Neurotrophin-3 human recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, >97% (SDS-PAGE)
N1780 Neurotrophin-4 human recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, >97% (SDS-PAGE)
N2513 NGF-β from rat recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture
N1408 NGF-β human from human, recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
SRP4304 NGF-beta from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
SRP6007 NT-3 from mouse recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
SRP3128 NT-3 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3129 NT-4 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3127 NT-1/BCSF-3 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3267 NT-3 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP6473 NTRK2/TRKB human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP6053 ProBDNF human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
SRP6054 ProNGF human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

Other growth factors/cytokines that affect neuronal populations

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SRP3114 Midkine human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
M3441 Midkine, human ≥90% (SDS-PAGE)
SRP3301 MIDKINE mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP3122 Neuritin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP6227 Neuritin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
SRP3143 Pleiotrophin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested