Platelet Derived Growth Factors (PDGF)

Platelet-Derived Growth Factor is the principal mitogen found in mammalian serum and is released from platelets during clot formation. PDGF elicits multifunctional actions with a variety of cells, including mitogenesis of mesoderm-derived cells, increased extracellular matrix synthesis, and chemotaxis and activation of neutrophils, monocytes and fibroblasts. PDGF is mitogenic for dermal and tendon fibroblasts, vascular smooth muscle cells, glial cells and chondrocytes. PDGF appears to interact with Transforming Growth Factor-1 in accelerating wound healing. However, PDGF may also be pathogenic in arteriosclerosis and neoplasia.

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Human recombinant PDGF proteins and receptors

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SRP3268 PDGF-AA human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP3138 PDGF-BB human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP6296 PDGF-BB human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP3139 PDGF-CC human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP0351 PDGFRb active human recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
SRP6498 PDGFRb/CD140b human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
P8147 Platelet-Derived Growth Factor from human platelets PDGF, 1 μg/vial, lyophilized powder, suitable for cell culture
P3076 Platelet-Derived Growth Factor-AA human PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
H8291 Platelet-Derived Growth Factor-AA human PDGF-AA, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
P3326 Platelet-Derived Growth Factor-AB human PDGF-AB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
P3201 Platelet-Derived Growth Factor-BB human PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
P4306 Platelet-Derived Growth Factor-BB human PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Mouse/Rat/Porcine recombinant PDGF proteins and receptors

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SRP3228 PDGF-AA from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3229 PDGF-BB from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
P8953 Platelet-Derived Growth Factor from porcine platelets PDGF, lyophilized powder, suitable for cell culture
P4056 Platelet-Derived Growth Factor-BB from rat PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture