Transforming Growth Factors

The transforming growth factor-ß (TGF-ß ) superfamily of cytokines include the structurally related subfamily of TGF-ß, the subfamily of bone morphogenic proteins (BMP), decapentaplegic (dpp) and Vg1, the subfamily of Mullerian inhibitory substances (MIS), and the subfamily of Activins and Inhibins. In general, individual members of this superfamily were originally purified and characterized with a specific functional assay, but most of these have broader biological activities that are particularly relevant in development. TGF-ß superfamily members have a conserved set of six cysteine residues that form a rigid ‘‘cysteine knot’’ in the carboxy terminal region. They are all secreted as large propeptide molecules which then form homodimers (or sometimes heterodimers with certain other superfamily members). Because TGF-ß and BMP receptors share close similarities, these two subfamilies frequently are grouped together.

Explore our high quality recombinant TGF pathway proteins for your research needs: TGF proteins, Bone Morphogenetic Proteins (BMP) and Activins.
Read about TGF signaling pathway here.
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Recombinant Activin proteins

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SRP6057 Activin A from mouse recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
A4941 Activin A human >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, cell culture tested
H4666 Activin A human recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
SRP6153 Activin A human recombinant, expressed in human cells, ≥95% (SDS-PAGE)
SRP3003 Activin A human recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC), cell culture tested
A1729 Activin B human recombinant, expressed in CHO cells, suitable for cell culture
SRP6200 Activin B human recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE)
A4362 Activin A active human Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE)

Recombinant Bone Morphogenetic Proteins (BMP)

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SRP6155 BMP-2 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP4573 BMP-3 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP6156 BMP-4 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP3016 BMP-4 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP3017 BMP-6 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP6157 BMP-7 human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
SRP4581 BMP-10 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP4576 BMP-11 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP4639 BMP-13 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
SRP6321 BMP-3b human recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
SRP6322 BMP8B human recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
B0814 BMP-7 active human Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE)
SRP4572 BMP-12/GDF-7 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP4580 BMP-14 (GDF-5/CDMP-1) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP3326 BMP-2 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP3260 BMP-4 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
SRP3279 BMP-5 human recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
SRP3298 BMP-4 mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
B3555 Bone Morphogenetic Protein 2 human ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
H4791 Bone Morphogenetic Protein 2 human BMP-2, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
B1814 Bone Morphogenetic Protein 2 human Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested
B2680 Bone Morphogenetic Protein 4 human >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, cell culture tested
H4916 Bone Morphogenetic Protein 4 human BMP-4, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
B2805 Bone Morphogenetic Protein 6 human >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, cell culture tested
B1434 Bone Morphogenetic Protein 7 human >95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, cell culture tested

Recombinant TGF proteins

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SRP4702 CTGF human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
SRP3022 CTGFL-WISP-2 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), cell culture tested
SRP6210 CTGFL/WISP-2 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
SRP6552 TGF-β3 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
T9580 TGF-β2 active human Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE)
T9705 TGF-β3 active Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE)
SRP3171 TGF-beta 3-E. coli human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
SRP0300 TGF-β1 Latent human recombinant, expressed in FreeStyle 293-F cells, ≥98% (SDS-PAGE)
T1654 Transforming Growth Factor-β1 from human platelets TGF-β1, lyophilized powder, suitable for cell culture, 1 × 106 U/mg
T7039 Transforming Growth Factor-β1 human TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture
H8541 Transforming Growth Factor-β1 human TGF-β1, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
T5300 Transforming Growth Factor-β2 from porcine platelets powder, suitable for cell culture
T2815 Transforming Growth Factor-β2 human TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture
H8666 Transforming Growth Factor-β2 human TGF-β2, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
T5425 Transforming Growth Factor-β3 human TGF-β3, recombinant, expressed in baculovirus infected Sf21 cells, powder, suitable for cell culture
H8791 Transforming Growth Factor-β3 human TGF-β3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
T7924 Transforming Growth Factor-α human TGF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
11412272001 Transforming Growth Factor-β1, human (hTGF-β1) recombinant (CHO cells)