"Good′s" Buffers refer to the group of buffers described in the research of Dr. Norman Good et al. in 1966. These buffers were selected because they display characteristics making them integral to research in biology and biochemistry. The characteristics associated with a Good′s buffer include the following: pKa value between 6.0 and 8.0, high solubility, non toxic, limited effect on biochemical reactions, very low absorbence between 240 nm and 700 nm, enzymatic and hydrolytic stability, minimal changes due to temperature and concentration, limited effects due to ionic or salt composition of the solution, limited interaction with mineral cations, and limited permeability of biological membranes. (Reference: Good, N.E., et al. (1966) Hydrogen Ion Buffers for Biological Research. Biochemistry 5(2), 467-477.)
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Buffer Reference Center .
Product #
Description
Useful pH Range
CAS Number
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GB11
“Good” buffers
A9758
ACES ≥99.0% (titration)
6.1 - 7.5
7365-82-4
6.8
A3594
ACES BioReagent, ≥99.0% (titration)
6.1 - 7.5
7365-82-4
6.8
A7949
ACES BioXtra, ≥99.0% (titration)
6.1 - 7.5
7365-82-4
6.8
A0153
ADA disodium salt
6.0 - 7.2
41689-31-0
6.6
A1925
ADA sodium salt ≥95% (titration)
6.0 - 7.2
7415-22-7
6.6
A9883
ADA ≥98% (titration)
6.0 - 7.2
26239-55-4
6.6
A8074
ADA BioXtra, ≥98% (titration)
6.0 - 7.2
26239-55-4
6.6
B2891
BES sodium salt ≥99% (titration)
6.4 - 7.8
66992-27-6
7.1
B9879
BES ≥99.0% (titration)
6.4 - 7.8
10191-18-1
7.1
B4554
BES BioReagent, cell culture tested, ≥99.0% (titration)
6.4 - 7.8
10191-18-1
7.1
B6420
BES BioXtra, ≥99.0% (titration)
6.4 - 7.8
10191-18-1
7.1
B3876
BICINE ≥99% (titration)
7.6 - 9.0
150-25-4
8.3
B8660
BICINE BioXtra, ≥99% (titration)
7.6 - 9.0
150-25-4
8.3
B6032
BIS-TRIS hydrochloride ≥99.0% (titration)
5.8 - 7.2
124763-51-5
6.5
B6755
BIS-TRIS propane ≥99.0% (titration)
6.3 - 9.5
64431-96-5
6.8
B4679
BIS-TRIS propane BioReagent, cell culture tested, ≥99.0% (titration)
6.3 - 9.5
64431-96-5
6.8
B9410
BIS-TRIS propane BioXtra, ≥99.0% (titration)
6.3 - 9.5
64431-96-5
6.8
B9754
BIS-TRIS ≥98.0% (titration)
5.8 - 7.2
6976-37-0
6.5
B4429
BIS-TRIS BioReagent, cell culture tested, suitable for insect cell culture, ≥98% (titration)
5.8 - 7.2
6976-37-0
6.5
B7535
BIS-TRIS BioXtra, ≥98.0% (titration)
5.8 - 7.2
6976-37-0
6.5
C2632
CAPS ≥98.0%
9.7 - 11.1
1135-40-6
10.4
C6070
CAPS BioXtra, pH 3.0-7.0 (20 °C, 0.5 M in H2 O), ≥98.0% NaOH basis (titration)
9.7 - 11.1
1135-40-6
10.4
C2154
CAPSO sodium salt
8.9 - 10.3
102601-34-3
9.6
C2278
CAPSO ≥99% anhydrous basis (titration)
8.9 - 10.3
73463-39-5
9.6
C2885
CHES ≥99.0% (titration)
8.6 - 10.0
103-47-9
9.3
C8210
CHES BioXtra, ≥99.0% (titration)
8.6 - 10.0
103-47-9
9.3
D0306
DIPSO BioXtra, pH 4.0-5.5 (20 °C, 0.1 M in H2 O), ≥98% (titration)
7.0 - 8.2
68399-80-4
7.6
E9502
EPPS ≥99.5% (titration)
7.3 - 8.7
16052-06-5
8
E1894
EPPS BioXtra, ≥99.5% (titration)
7.3 - 8.7
16052-06-5
8
E0276
EPPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)
7.3 - 8.7
16052-06-5
8
G1002
Gly-Gly ≥99% (titration)
7.5 - 8.9
556-50-3
8.2
G3915
Gly-Gly BioReagent, cell culture tested, ≥99% (titration)
7.5 - 8.9
556-50-3
8.2
H6903
HEPBS ≥99% (titration)
7.6 - 9.0
161308-36-7
8.3
83264
HEPES buffer solution 1 M in H2 O
7365-45-9
H7637
HEPES hemisodium salt ≥99% (titration)
6.8 - 8.2
103404-87-1
7.5
H9897
HEPES hemisodium salt dry powder
6.8 - 8.2
103404-87-1
7.5
H0527
HEPES potassium salt ≥99.5% (titration)
6.8 - 8.2
82207-62-3
7.5
H2393
HEPES sodium salt hydrate ≥99% (titration)
6.8 - 8.2
75277-39-3
7.5
H3662
HEPES sodium salt solution 1M, BioReagent, suitable for cell culture
75277-39-3
H7006
HEPES sodium salt ≥99.5% (titration)
6.8 - 8.2
75277-39-3
7.5
H3784
HEPES sodium salt BioReagent, suitable for cell culture, ≥99.5% (titration)
6.8 - 8.2
75277-39-3
7.5
H8651
HEPES sodium salt BioXtra, ≥99.5% (titration)
6.8 - 8.2
75277-39-3
7.5
H3537
HEPES solution 1 M, BioReagent, suitable for cell culture, suitable for molecular biology, 0.2 μm filtered
6.8 - 8.2
7365-45-9
H3375
HEPES ≥99.5% (titration)
6.8 - 8.2
7365-45-9
7.5
H7523
HEPES BioXtra, pH 5.0-6.5 (1 M in H2 O), ≥99.5% (titration)
6.8 - 8.2
7365-45-9
7.5
H4034
HEPES Biotechnology Performance Certified, ≥99.5% (titration), cell culture tested
6.8 - 8.2
7365-45-9
7.5
M8902
MES hemisodium salt ≥98% (titration)
5.5 - 6.7
117961-21-4
6.1
M0164
MES hemisodium salt dry powder
5.5 - 6.7
117961-21-4
6.1
M8250
MES hydrate ≥99.5% (titration)
5.5 - 6.7
4432-31-9 (anhydrous)
6.1
M5287
MES hydrate ≥99.5% (titration), pH 2.5-4.0 (0.5 M in H2 O), BioXtra
5.5 - 6.7
4432-31-9 (anhydrous)
6.1
M2933
MES hydrate BioReagent, suitable for cell culture, for molecular biology, ≥99.5%
5.5 - 6.7
4432-31-9 (anhydrous)
6.1
M0895
MES potassium salt ≥99% (titration)
5.5 - 6.7
39946-25-3
6.1
M3885
MES sodium salt ≥99% (titration)
5.5 - 6.7
71119-23-8
6.1
M5057
MES sodium salt BioReagent, ≥99% (titration), crystalline
5.5 - 6.7
71119-23-8
6.1
M3058
MES sodium salt BioReagent, suitable for cell culture, for molecular biology
5.5 - 6.7
71119-23-8
6.1
M1317
MES solution 1 M, BioReagent, for molecular biology, suitable for cell culture
5.5 - 6.7
M3671
MES low moisture content, ≥99% (titration)
5.5 - 6.7
4432-31-9
6.1
M3295
MOBS ≥99% (titration)
6.9 - 8.3
115724-21-5
7.6
M9027
MOPS hemisodium salt ≥99% (titration)
6.5 - 7.9
117961-20-3
7.2
M0289
MOPS hemisodium salt foil pouch
6.5 - 7.9
117961-20-3
7.2
M9381
MOPS sodium salt ≥99.5% (titration)
6.5 - 7.9
71119-22-7
7.2
M9024
MOPS sodium salt BioReagent, suitable for cell culture, ≥99.5% (titration)
6.5 - 7.9
71119-22-7
7.2
M5789
MOPS sodium salt BioXtra, ≥99.5% anhydrous basis (titration)
6.5 - 7.9
71119-22-7
7.2
M1442
MOPS solution BioReagent, 1 M, for molecular biology, suitable for cell culture
6.5 - 7.9
M1254
MOPS ≥99.5% (titration)
6.5 - 7.9
1132-61-2
7.2
M5162
MOPS BioXtra, ≥99.5% (titration)
6.5 - 7.9
1132-61-2
7.2
M3183
MOPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)
6.5 - 7.9
1132-61-2
7.2
M8767
MOPSO sodium salt ≥99% (titration)
6.2 - 7.6
79803-73-9
6.9
M5914
MOPSO sodium salt BioXtra, pH 10.0-12.0 (1 M in H2 O), ≥99% (titration)
6.2 - 7.6
79803-73-9
6.9
M8389
MOPSO ≥99% (titration)
6.2 - 7.6
68399-77-9
6.9
P7643
PIPES dipotassium salt ≥99% (titration)
6.1 - 7.5
108321-27-3
6.8
P3768
PIPES disodium salt ≥99% (titration)
6.1 - 7.5
76836-02-7
6.8
P8655
PIPES sesquisodium salt ≥99% (titration)
6.1 - 7.5
100037-69-2
6.8
P2949
PIPES sodium salt ≥99% (titration)
6.1 - 7.5
10010-67-0
6.8
P6757
PIPES ≥99% (titration)
6.1 - 7.5
5625-37-6
6.8
P1851
PIPES BioReagent, suitable for cell culture, ≥99% (titration), for molecular biology
6.1 - 7.5
5625-37-6
6.8
P8203
PIPES BioXtra, ≥99% (titration)
6.1 - 7.5
5625-37-6
6.8
P7905
POPSO disodium salt
7.2 - 8.5
108321-07-9
7.8
P3405
POPSO hydrate ≥99% (titration)
7.2 - 8.5
68189-43-5 (anhydrous)
7.8
P8907
POPSO sesquisodium salt ≥98% (titration)
7.2 - 8.5
108321-08-0
7.8
T0647
TAPS sodium salt ≥99% (titration)
7.7 - 9.1
91000-53-2
8.4
T5441
TAPS sodium salt BioReagent, suitable for cell culture, for molecular biology, ≥99%
7.7 - 9.1
91000-53-2
8.4
T5130
TAPS ≥99.5% (titration)
7.7 - 9.1
29915-38-6
8.4
T9659
TAPS BioXtra, ≥99.5% (titration)
7.7 - 9.1
29915-38-6
8.4
T5316
TAPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)
7.7 - 9.1
29915-38-6
8.4
T5395
TAPSO sodium salt
7.0 - 8.2
105140-25-8
7.6
T9269
TAPSO ≥99% (titration)
7.0 - 8.2
68399-81-5
7.6
T0432
TAPSO BioXtra, ≥99% (titration)
7.0 - 8.2
68399-81-5
7.6
T1030
TES hemisodium salt
6.8 - 8.2
7.5
T0772
TES sodium salt ≥99% (titration)
6.8 - 8.2
70331-82-7
7.5
T1375
TES ≥99% (titration)
6.8 - 8.2
7365-44-8
7.5
T6541
TES BioXtra, ≥99.5% (titration)
6.8 - 8.2
7365-44-8
7.5
T5691
TES Biotechnology Performance Certified, cell culture tested, ≥99% (titration)
6.8 - 8.2
7365-44-8
7.5
93318
TRIS buffered saline caplets (for 15 mL), pH 7.6
T0377
Tricine ≥99% (titration)
7.4 - 8.8
5704-04-1
8.1
T9784
Tricine BioXtra, pH 4.0-6.0 (1 M in H2 O), ≥99% (titration)
7.4 - 8.8
5704-04-1
8.1
T5816
Tricine Biotechnology Performance Certified, cell culture tested, ≥99% (titration)
7.4 - 8.8
5704-04-1
8.1
93367
Trizma® Buffer substance for fish-farming, pH 8.3
93369
Trizma® Buffer substance pH 7.2
93371
Trizma® Buffer substance pH 7.4
93372
Trizma® Buffer substance pH 7.5
93374
Trizma® Buffer substance pH 7.6
93376
Trizma® Buffer substance pH 7.7
93377
Trizma® Buffer substance pH 7.8
93378
Trizma® Buffer substance pH 8.0
93379
Trizma® Buffer substance pH 8.1
93389
Trizma® Buffer substance pH 8.3
93392
Trizma® Buffer substance pH 8.8
93394
Trizma® Buffer substance pH 9.0
T8508
Trizma® Pre-Set Crystals Type 7.2-FT, pH 7.2, suitable for use with fresh water species
T1753
Trizma® Pre-Set Crystals Type 7.4-FT, pH 7.4, suitable for use with fresh water species
T1878
Trizma® Pre-Set crystals Type 8.3-FT, pH 8.3, suitable for use with marine species
T7193
Trizma® Pre-set crystals pH 7.0, average Mw 154.8
7.0 - 9.0
T9943
Trizma® Pre-set crystals pH 7.0, average Mw 154.8
7.0 - 9.0
T7443
Trizma® Pre-set crystals pH 7.2, average Mw 153.8
7.0 - 9.0
T7693
Trizma® Pre-set crystals pH 7.4, average Mw 151.6
7.0 - 9.0
T0319
Trizma® Pre-set crystals pH 7.4, average Mw 151.6
7.0 - 9.0
T7818
Trizma® Pre-set crystals pH 7.5, average Mw 150.6
7.0 - 9.0
T0444
Trizma® Pre-set crystals pH 7.5, average Mw 150.6
7.0 - 9.0
T7943
Trizma® Pre-set crystals pH 7.6, average Mw 149.0
7.0 - 9.0
T0569
Trizma® Pre-set crystals pH 7.6, average Mw 149.0
7.0 - 9.0
T8068
Trizma® Pre-set crystals pH 7.7, average Mw 147.6
7.0 - 9.0
T0694
Trizma® Pre-set crystals pH 7.7, average Mw 147.6
7.0 - 9.0
T8193
Trizma® Pre-set crystals pH 7.8, average Mw 145.8
7.0 - 9.0
T8443
Trizma® Pre-set crystals pH 8.0, average Mw 141.8
7.0 - 9.0
T0819
Trizma® Pre-set crystals pH 8.0, average Mw 141.8
7.0 - 9.0
T8568
Trizma® Pre-set crystals pH 8.1, average Mw 139.8
7.0 - 9.0
T8943
Trizma® Pre-set crystals pH 8.3, average Mw 135.4
7.0 - 9.0
T8818
Trizma® Pre-set crystals pH 8.5, average Mw 131.4
7.0 - 9.0
T1194
Trizma® Pre-set crystals pH 8.5, average Mw 131.4
7.0 - 9.0
T9443
Trizma® Pre-set crystals pH 8.8, average Mw 127.2
7.0 - 9.0
T9568
Trizma® Pre-set crystals pH 8.9, average Mw 125.6
7.0 - 9.0
T9693
Trizma® Pre-set crystals pH 9.0, average Mw 124.6
7.0 - 9.0
T1444
Trizma® Pre-set crystals pH 9.0, average Mw 124.6
7.0 - 9.0
T9818
Trizma® Pre-set crystals pH 9.1, average Mw 123.0
7.0 - 9.0
T4661
Trizma® base ≥99.9% (titration), crystalline
7 - 9
77-86-1
8.1
T6791
Trizma® base BioXtra, pH 10.5-12.0 (1 M in H2 O), ≥99.9% (titration)
7 - 9
77-86-1
8.1
T6066
Trizma® base Biotechnology Performance Certified, meets EP, USP testing specifications, cell culture tested, ≥99.9% (titration)
7 - 9
77-86-1
8.1
T1503
Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline
7 - 9
77-86-1
8.1
93350
Trizma® base puriss. p.a., ≥99.7% (T)
7 - 9
77-86-1
8.1
T1819
Trizma® hydrochloride solution pH 7.0, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2069
Trizma® hydrochloride solution pH 7.2, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T1944
Trizma® hydrochloride solution pH 7.4, 0.1 M
7.0 - 9.0
T2194
Trizma® hydrochloride solution pH 7.4, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2319
Trizma® hydrochloride solution pH 7.5, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2944
Trizma® hydrochloride solution pH 7.5, 2 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2444
Trizma® hydrochloride solution pH 7.6, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2569
Trizma® hydrochloride solution pH 7.8, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2694
Trizma® hydrochloride solution pH 8.0, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T3069
Trizma® hydrochloride solution pH 8.0, 2 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T2819
Trizma® hydrochloride solution pH 9.0, 1 M, BioReagent, for molecular biology, suitable for cell culture
7.0 - 9.0
T6666
Trizma® hydrochloride BioXtra, pH 3.5-5.0 (0.5 M in H2 O), ≥99.0% (titration)
7.0 - 9.0
1185-53-1
8.1
T5941
Trizma® hydrochloride for molecular biology, Biotechnology Performance Certified, cell culture tested, ≥99.0% (titration)
7.0 - 9.0
1185-53-1
8.1
T3253
Trizma® hydrochloride reagent grade, ≥99.0% (titration), crystalline
7.0 - 9.0
1185-53-1
8.1