Good’s Buffers

"Good′s" Buffers refer to the group of buffers described in the research of Dr. Norman Good et al. in 1966. These buffers were selected because they display characteristics making them integral to research in biology and biochemistry. The characteristics associated with a Good′s buffer include the following: pKa value between 6.0 and 8.0, high solubility, non toxic, limited effect on biochemical reactions, very low absorbence between 240 nm and 700 nm, enzymatic and hydrolytic stability, minimal changes due to temperature and concentration, limited effects due to ionic or salt composition of the solution, limited interaction with mineral cations, and limited permeability of biological membranes. (Reference: Good, N.E., et al. (1966) Hydrogen Ion Buffers for Biological Research. Biochemistry 5(2), 467-477.)

For additional technical details, visit the Buffer Reference Center.

Product #

Description

Useful pH Range

CAS Number

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GB11 “Good” buffers      
    • A9758 ACES ≥99.0% (titration) 6.1 - 7.5
    		 7365-82-4 6.8
    • A3594 ACES BioReagent, ≥99.0% (titration) 6.1 - 7.5
    		 7365-82-4 6.8
    • A7949 ACES BioXtra, ≥99.0% (titration) 6.1 - 7.5
    		 7365-82-4 6.8
    • A0153 ADA disodium salt 6.0 - 7.2
    		 41689-31-0 6.6
    • A1925 ADA sodium salt ≥95% (titration) 6.0 - 7.2
    		 7415-22-7 6.6
    • A9883 ADA ≥98% (titration) 6.0 - 7.2
    		 26239-55-4 6.6
    • A8074 ADA BioXtra, ≥98% (titration) 6.0 - 7.2
    		 26239-55-4 6.6
    • B2891 BES sodium salt ≥99% (titration) 6.4 - 7.8
    		 66992-27-6 7.1
    • B9879 BES ≥99.0% (titration) 6.4 - 7.8
    		 10191-18-1 7.1
    • B4554 BES BioReagent, cell culture tested, ≥99.0% (titration) 6.4 - 7.8
    		 10191-18-1 7.1
    • B6420 BES BioXtra, ≥99.0% (titration) 6.4 - 7.8
    		 10191-18-1 7.1
    • B3876 BICINE ≥99% (titration) 7.6 - 9.0
    		 150-25-4 8.3
    • B8660 BICINE BioXtra, ≥99% (titration) 7.6 - 9.0
    		 150-25-4 8.3
    • B6032 BIS-TRIS hydrochloride ≥99.0% (titration) 5.8 - 7.2
    		 124763-51-5 6.5
    • B6755 BIS-TRIS propane ≥99.0% (titration) 6.3 - 9.5
    		 64431-96-5 6.8
    • B4679 BIS-TRIS propane BioReagent, cell culture tested, ≥99.0% (titration) 6.3 - 9.5
    		 64431-96-5 6.8
    • B9410 BIS-TRIS propane BioXtra, ≥99.0% (titration) 6.3 - 9.5
    		 64431-96-5 6.8
    • B9754 BIS-TRIS ≥98.0% (titration) 5.8 - 7.2
    		 6976-37-0 6.5
    • B4429 BIS-TRIS BioReagent, cell culture tested, suitable for insect cell culture, ≥98% (titration) 5.8 - 7.2
    		 6976-37-0 6.5
    • B7535 BIS-TRIS BioXtra, ≥98.0% (titration) 5.8 - 7.2
    		 6976-37-0 6.5
    • C2632 CAPS ≥98.0% 9.7 - 11.1
    		 1135-40-6 10.4
    • C6070 CAPS BioXtra, pH 3.0-7.0 (20 °C, 0.5 M in H2O), ≥98.0% NaOH basis (titration) 9.7 - 11.1
    		 1135-40-6 10.4
    • C2154 CAPSO sodium salt 8.9 - 10.3
    		 102601-34-3 9.6
    • C2278 CAPSO ≥99% anhydrous basis (titration) 8.9 - 10.3
    		 73463-39-5 9.6
    • C2885 CHES ≥99.0% (titration) 8.6 - 10.0
    		 103-47-9 9.3
    • C8210 CHES BioXtra, ≥99.0% (titration) 8.6 - 10.0
    		 103-47-9 9.3
    • D0306 DIPSO BioXtra, pH 4.0-5.5 (20 °C, 0.1 M in H2O), ≥98% (titration) 7.0 - 8.2
    		 68399-80-4 7.6
    • E9502 EPPS ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • E1894 EPPS BioXtra, ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • E0276 EPPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration) 7.3 - 8.7
    		 16052-06-5 8
    • G1002 Gly-Gly ≥99% (titration) 7.5 - 8.9
    		 556-50-3 8.2
    • G3915 Gly-Gly BioReagent, cell culture tested, ≥99% (titration) 7.5 - 8.9
    		 556-50-3 8.2
    • H6903 HEPBS ≥99% (titration) 7.6 - 9.0
    		 161308-36-7 8.3
    • 83264 HEPES buffer solution 1 M in H2O   7365-45-9  
    • H7637 HEPES hemisodium salt ≥99% (titration) 6.8 - 8.2
    		 103404-87-1 7.5
    • H9897 HEPES hemisodium salt dry powder 6.8 - 8.2
    		 103404-87-1 7.5
    • H0527 HEPES potassium salt ≥99.5% (titration) 6.8 - 8.2
    		 82207-62-3 7.5
    • H2393 HEPES sodium salt hydrate ≥99% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H3662 HEPES sodium salt solution 1M, BioReagent, suitable for cell culture   75277-39-3  
    • H7006 HEPES sodium salt ≥99.5% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H3784 HEPES sodium salt BioReagent, suitable for cell culture, ≥99.5% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H8651 HEPES sodium salt BioXtra, ≥99.5% (titration) 6.8 - 8.2
    		 75277-39-3 7.5
    • H3537 HEPES solution 1 M, BioReagent, suitable for cell culture, suitable for molecular biology, 0.2 μm filtered 6.8 - 8.2
    		 7365-45-9  
    • H3375 HEPES ≥99.5% (titration) 6.8 - 8.2
    		 7365-45-9 7.5
    • H7523 HEPES BioXtra, pH 5.0-6.5 (1 M in H2O), ≥99.5% (titration) 6.8 - 8.2
    		 7365-45-9 7.5
    • H4034 HEPES Biotechnology Performance Certified, ≥99.5% (titration), cell culture tested 6.8 - 8.2
    		 7365-45-9 7.5
    • M8902 MES hemisodium salt ≥98% (titration) 5.5 - 6.7
    		 117961-21-4 6.1
    • M0164 MES hemisodium salt dry powder 5.5 - 6.7
    		 117961-21-4 6.1
    • M8250 MES hydrate ≥99.5% (titration) 5.5 - 6.7
    		 4432-31-9 (anhydrous) 6.1
    • M5287 MES hydrate ≥99.5% (titration), pH 2.5-4.0 (0.5 M in H2O), BioXtra 5.5 - 6.7
    		 4432-31-9 (anhydrous) 6.1
    • M2933 MES hydrate BioReagent, suitable for cell culture, for molecular biology, ≥99.5% 5.5 - 6.7
    		 4432-31-9 (anhydrous) 6.1
    • M0895 MES potassium salt ≥99% (titration) 5.5 - 6.7
    		 39946-25-3 6.1
    • M3885 MES sodium salt ≥99% (titration) 5.5 - 6.7
    		 71119-23-8 6.1
    • M5057 MES sodium salt BioReagent, ≥99% (titration), crystalline 5.5 - 6.7
    		 71119-23-8 6.1
    • M3058 MES sodium salt BioReagent, suitable for cell culture, for molecular biology 5.5 - 6.7
    		 71119-23-8 6.1
    • M1317 MES solution 1 M, BioReagent, for molecular biology, suitable for cell culture 5.5 - 6.7
    		    
    • M3671 MES low moisture content, ≥99% (titration) 5.5 - 6.7
    		 4432-31-9 6.1
    • M3295 MOBS ≥99% (titration) 6.9 - 8.3
    		 115724-21-5 7.6
    • M9027 MOPS hemisodium salt ≥99% (titration) 6.5 - 7.9
    		 117961-20-3 7.2
    • M0289 MOPS hemisodium salt foil pouch 6.5 - 7.9
    		 117961-20-3 7.2
    • M9381 MOPS sodium salt ≥99.5% (titration) 6.5 - 7.9
    		 71119-22-7 7.2
    • M9024 MOPS sodium salt BioReagent, suitable for cell culture, ≥99.5% (titration) 6.5 - 7.9
    		 71119-22-7 7.2
    • M5789 MOPS sodium salt BioXtra, ≥99.5% anhydrous basis (titration) 6.5 - 7.9
    		 71119-22-7 7.2
    • M1442 MOPS solution BioReagent, 1 M, for molecular biology, suitable for cell culture 6.5 - 7.9
    		    
    • M1254 MOPS ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M5162 MOPS BioXtra, ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M3183 MOPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration) 6.5 - 7.9
    		 1132-61-2 7.2
    • M8767 MOPSO sodium salt ≥99% (titration) 6.2 - 7.6
    		 79803-73-9 6.9
    • M5914 MOPSO sodium salt BioXtra, pH 10.0-12.0 (1 M in H2O), ≥99% (titration) 6.2 - 7.6
    		 79803-73-9 6.9
    • M8389 MOPSO ≥99% (titration) 6.2 - 7.6
    		 68399-77-9 6.9
    • P7643 PIPES dipotassium salt ≥99% (titration) 6.1 - 7.5
    		 108321-27-3 6.8
    • P3768 PIPES disodium salt ≥99% (titration) 6.1 - 7.5
    		 76836-02-7 6.8
    • P8655 PIPES sesquisodium salt ≥99% (titration) 6.1 - 7.5
    		 100037-69-2 6.8
    • P2949 PIPES sodium salt ≥99% (titration) 6.1 - 7.5
    		 10010-67-0 6.8
    • P6757 PIPES ≥99% (titration) 6.1 - 7.5
    		 5625-37-6 6.8
    • P1851 PIPES BioReagent, suitable for cell culture, ≥99% (titration), for molecular biology 6.1 - 7.5
    		 5625-37-6 6.8
    • P8203 PIPES BioXtra, ≥99% (titration) 6.1 - 7.5
    		 5625-37-6 6.8
    • P7905 POPSO disodium salt 7.2 - 8.5
    		 108321-07-9 7.8
    • P3405 POPSO hydrate ≥99% (titration) 7.2 - 8.5
    		 68189-43-5 (anhydrous) 7.8
    • P8907 POPSO sesquisodium salt ≥98% (titration) 7.2 - 8.5
    		 108321-08-0 7.8
    • T0647 TAPS sodium salt ≥99% (titration) 7.7 - 9.1
    		 91000-53-2 8.4
    • T5441 TAPS sodium salt BioReagent, suitable for cell culture, for molecular biology, ≥99% 7.7 - 9.1
    		 91000-53-2 8.4
    • T5130 TAPS ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T9659 TAPS BioXtra, ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T5316 TAPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration) 7.7 - 9.1
    		 29915-38-6 8.4
    • T5395 TAPSO sodium salt 7.0 - 8.2
    		 105140-25-8 7.6
    • T9269 TAPSO ≥99% (titration) 7.0 - 8.2
    		 68399-81-5 7.6
    • T0432 TAPSO BioXtra, ≥99% (titration) 7.0 - 8.2
    		 68399-81-5 7.6
    • T1030 TES hemisodium salt 6.8 - 8.2
    		   7.5
    • T0772 TES sodium salt ≥99% (titration) 6.8 - 8.2
    		 70331-82-7 7.5
    • T1375 TES ≥99% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • T6541 TES BioXtra, ≥99.5% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • T5691 TES Biotechnology Performance Certified, cell culture tested, ≥99% (titration) 6.8 - 8.2
    		 7365-44-8 7.5
    • 93318 TRIS buffered saline caplets (for 15 mL), pH 7.6      
    • T0377 Tricine ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • T9784 Tricine BioXtra, pH 4.0-6.0 (1 M in H2O), ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • T5816 Tricine Biotechnology Performance Certified, cell culture tested, ≥99% (titration) 7.4 - 8.8
    		 5704-04-1 8.1
    • 93367 Trizma® Buffer substance for fish-farming, pH 8.3      
    • 93369 Trizma® Buffer substance pH 7.2      
    • 93371 Trizma® Buffer substance pH 7.4      
    • 93372 Trizma® Buffer substance pH 7.5      
    • 93374 Trizma® Buffer substance pH 7.6      
    • 93376 Trizma® Buffer substance pH 7.7      
    • 93377 Trizma® Buffer substance pH 7.8      
    • 93378 Trizma® Buffer substance pH 8.0      
    • 93379 Trizma® Buffer substance pH 8.1      
    • 93389 Trizma® Buffer substance pH 8.3      
    • 93392 Trizma® Buffer substance pH 8.8      
    • 93394 Trizma® Buffer substance pH 9.0      
    • T8508 Trizma® Pre-Set Crystals Type 7.2-FT, pH 7.2, suitable for use with fresh water species      
    • T1753 Trizma® Pre-Set Crystals Type 7.4-FT, pH 7.4, suitable for use with fresh water species      
    • T1878 Trizma® Pre-Set crystals Type 8.3-FT, pH 8.3, suitable for use with marine species      
    • T7193 Trizma® Pre-set crystals pH 7.0, average Mw 154.8 7.0 - 9.0
    		    
    • T9943 Trizma® Pre-set crystals pH 7.0, average Mw 154.8 7.0 - 9.0
    		    
    • T7443 Trizma® Pre-set crystals pH 7.2, average Mw 153.8 7.0 - 9.0
    		    
    • T7693 Trizma® Pre-set crystals pH 7.4, average Mw 151.6 7.0 - 9.0
    		    
    • T0319 Trizma® Pre-set crystals pH 7.4, average Mw 151.6 7.0 - 9.0
    		    
    • T7818 Trizma® Pre-set crystals pH 7.5, average Mw 150.6 7.0 - 9.0
    		    
    • T0444 Trizma® Pre-set crystals pH 7.5, average Mw 150.6 7.0 - 9.0
    		    
    • T7943 Trizma® Pre-set crystals pH 7.6, average Mw 149.0 7.0 - 9.0
    		    
    • T0569 Trizma® Pre-set crystals pH 7.6, average Mw 149.0 7.0 - 9.0
    		    
    • T8068 Trizma® Pre-set crystals pH 7.7, average Mw 147.6 7.0 - 9.0
    		    
    • T0694 Trizma® Pre-set crystals pH 7.7, average Mw 147.6 7.0 - 9.0
    		    
    • T8193 Trizma® Pre-set crystals pH 7.8, average Mw 145.8 7.0 - 9.0
    		    
    • T8443 Trizma® Pre-set crystals pH 8.0, average Mw 141.8 7.0 - 9.0
    		    
    • T0819 Trizma® Pre-set crystals pH 8.0, average Mw 141.8 7.0 - 9.0
    		    
    • T8568 Trizma® Pre-set crystals pH 8.1, average Mw 139.8 7.0 - 9.0
    		    
    • T8943 Trizma® Pre-set crystals pH 8.3, average Mw 135.4 7.0 - 9.0
    		    
    • T8818 Trizma® Pre-set crystals pH 8.5, average Mw 131.4 7.0 - 9.0
    		    
    • T1194 Trizma® Pre-set crystals pH 8.5, average Mw 131.4 7.0 - 9.0
    		    
    • T9443 Trizma® Pre-set crystals pH 8.8, average Mw 127.2 7.0 - 9.0
    		    
    • T9568 Trizma® Pre-set crystals pH 8.9, average Mw 125.6 7.0 - 9.0
    		    
    • T9693 Trizma® Pre-set crystals pH 9.0, average Mw 124.6 7.0 - 9.0
    		    
    • T1444 Trizma® Pre-set crystals pH 9.0, average Mw 124.6 7.0 - 9.0
    		    
    • T9818 Trizma® Pre-set crystals pH 9.1, average Mw 123.0 7.0 - 9.0
    		    
    • T4661 Trizma® base ≥99.9% (titration), crystalline 7 - 9
    		 77-86-1 8.1
    • T6791 Trizma® base BioXtra, pH 10.5-12.0 (1 M in H2O), ≥99.9% (titration) 7 - 9
    		 77-86-1 8.1
    • T6066 Trizma® base Biotechnology Performance Certified, meets EP, USP testing specifications, cell culture tested, ≥99.9% (titration) 7 - 9
    		 77-86-1 8.1
    • T1503 Trizma® base Primary Standard and Buffer, ≥99.9% (titration), crystalline 7 - 9
    		 77-86-1 8.1
    • 93350 Trizma® base puriss. p.a., ≥99.7% (T) 7 - 9
    		 77-86-1 8.1
    • T1819 Trizma® hydrochloride solution pH 7.0, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2069 Trizma® hydrochloride solution pH 7.2, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T1944 Trizma® hydrochloride solution pH 7.4, 0.1 M 7.0 - 9.0
    		    
    • T2194 Trizma® hydrochloride solution pH 7.4, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2319 Trizma® hydrochloride solution pH 7.5, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2944 Trizma® hydrochloride solution pH 7.5, 2 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2444 Trizma® hydrochloride solution pH 7.6, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2569 Trizma® hydrochloride solution pH 7.8, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2694 Trizma® hydrochloride solution pH 8.0, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T3069 Trizma® hydrochloride solution pH 8.0, 2 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T2819 Trizma® hydrochloride solution pH 9.0, 1 M, BioReagent, for molecular biology, suitable for cell culture 7.0 - 9.0
    		    
    • T6666 Trizma® hydrochloride BioXtra, pH 3.5-5.0 (0.5 M in H2O), ≥99.0% (titration) 7.0 - 9.0
    		 1185-53-1 8.1
    • T5941 Trizma® hydrochloride for molecular biology, Biotechnology Performance Certified, cell culture tested, ≥99.0% (titration) 7.0 - 9.0
    		 1185-53-1 8.1
    • T3253 Trizma® hydrochloride reagent grade, ≥99.0% (titration), crystalline 7.0 - 9.0
    		 1185-53-1 8.1