Good’s Buffers

"Good's" Buffers refer to the group of buffers described in the research of Dr. Norman Good et al. in 1966. These buffers were selected because they display characteristics making them integral to research in biology and biochemistry. The characteristics associated with a Good's buffer include the following: pKa value between 6.0 and 8.0, high solubility, non toxic, limited effect on biochemical reactions, very low absorbence between 240 nm and 700 nm, enzymatic and hydrolytic stability, minimal changes due to temperature and concentration, limited effects due to ionic or salt composition of the solution, limited interaction with mineral cations, and limited permeability of biological membranes. (Reference: Good, N.E., et al. (1966) Hydrogen Ion Buffers for Biological Research. Biochemistry 5(2), 467-477.)

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“Good” buffers

ACES ≥99.0% (titration)

6.1 - 7.5

6.8

ACES Biotechnology Performance Certified, ≥99.0% (titration)

6.1 - 7.5

6.8

ACES SigmaUltra, ≥99.0% (titration)

6.1 - 7.5

6.8

ADA disodium salt

6.0 - 7.2

6.6

ADA sodium salt ≥95% (titration)

6.0 - 7.2

6.6

ADA ≥98% (titration)

6.0 - 7.2

6.6

ADA SigmaUltra, ≥98% (titration)

6.0 - 7.2

6.6

BES sodium salt

6.4 - 7.8

7.1

BES ≥99.0% (titration)

6.4 - 7.8

7.1

BES Biotechnology Performance Certified, cell culture tested, ≥99.0% (titration)

6.4 - 7.8

7.1

BES SigmaUltra, ≥99.0% (titration)

6.4 - 7.8

7.1

BICINE ≥99% (titration)

7.6 - 9.0

8.3

BICINE SigmaUltra, ≥99% (titration)

7.6 - 9.0

8.3

BIS-TRIS hydrochloride ≥98% (titration)

5.8 - 7.2

6.5

BIS-TRIS propane ≥99.0% (titration)

6.3 - 9.5

6.8

BIS-TRIS propane Biotechnology Performance Certified, cell culture tested, ≥99.0% (titration)

6.3 - 9.5

6.8

BIS-TRIS propane SigmaUltra, ≥99.0% (titration)

6.3 - 9.5

6.8

BIS-TRIS ≥98.0% (titration)

5.8 - 7.2

6.5

BIS-TRIS Biotechnology Performance Certified, cell culture tested, insect cell culture tested, ≥98% (titration)

5.8 - 7.2

6.5

BIS-TRIS SigmaUltra, ≥98.0% (titration)

5.8 - 7.2

6.5

CAPS ≥98.0%

9.7 - 11.1
9.7 - 11.1

10.4

CAPSO sodium salt

8.9 - 10.3

9.6

CAPSO ≥99% anhydrous basis (titration)

8.9 - 10.3

9.6

CAPSO SigmaUltra, pH 2.0-4.0 (20 °C, 0.5 M in H₂O), ≥99.0% anhydrous basis (TSOD, titration)

8.9 - 10.3

9.6

CAPS SigmaUltra, pH 3.0-7.0 (20 °C, 0.5 M in H₂O), ≥98.0% NaOH basis (titration)

9.7 - 11.1
9.7 - 11.1

10.4

CHES ≥99% (titration)

8.6 - 10.0

9.3

CHES SigmaUltra, ≥99% (titration)

8.6 - 10.0

9.3

DIPSO ≥99% (titration)

7.0 - 8.2

7.6

DIPSO SigmaUltra, pH 4.0-5.5 (20 °C, 0.1 M in H₂O), ≥98% (titration)

7.0 - 8.2

7.6

EPPS ≥99.5% (titration)

7.3 - 8.7
7.3 - 8.7

8

EPPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)

7.3 - 8.7
7.3 - 8.7

8

EPPS SigmaUltra, ≥99.5% (titration)

7.3 - 8.7

8

Gly-Gly ≥99% (titration)

7.5 - 8.9
7.5 - 8.9

8.2

Gly-Gly Biotechnology Performance Certified, cell culture tested, plant cell culture tested, ≥99% (titration)

7.5 - 8.9
7.5 - 8.9

8.2

Gly-Gly SigmaUltra, pH 4.5-6.0 (20 °C, 1 M in H₂O), >99.5% (titration)

7.5 - 8.9

8.2

HEPBS ≥99% (titration)

7.6 - 9.0
7.6 - 9.0

8.3

HEPES buffer solution BioChemika, 1 M in H₂O

HEPES hemisodium salt ≥99% (titration)

6.8 - 8.2

7.5

HEPES hemisodium salt dry powder

6.8 - 8.2

7.5

HEPES potassium salt ≥99.5% (titration)

6.8 - 8.2

7.5

HEPES sodium salt hydrate ≥99% (titration)

6.8 - 8.2

7.5

HEPES sodium salt solution 1M, Cell Culture tested, Biotechnology Performance Certified

HEPES sodium salt ≥99.5% (titration)

6.8 - 8.2

7.5

HEPES sodium salt Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)

6.8 - 8.2

7.5

HEPES sodium salt SigmaUltra, ≥99.5% (titration)

6.8 - 8.2

7.5

HEPES solution 1 M, Cell Culture tested, Biotechnology Performance Certified

6.8 - 8.2

HEPES ≥99.5% (titration)

6.8 - 8.2

7.5

HEPES Biotechnology Performance Certified, ≥99.5% (titration), cell culture tested

6.8 - 8.2

7.5

HEPES SigmaUltra, pH 5.0-6.5 (20 °C, 1 M in H₂O), ≥99.5% (titration)

6.8 - 8.2

7.5

HEPPSO Hydrate ≥99% (titration)

7.1 - 8.5

7.5

HEPPSO sodium salt

7.1 - 8.5

7.8

MES hemisodium salt ≥98% (titration)

5.5 - 6.7

6.1

MES hemisodium salt dry powder

5.5 - 6.7

6.1

MES hydrate ≥99.5% (titration)

5.5 - 6.7

4432-31-9 (anhydrous)

6.1

MES hydrate ≥99.5% (titration), pH 2.5-4.0 (20 °C, 0.5 M in H₂O), SigmaUltra

5.5 - 6.7

4432-31-9 (anhydrous)

6.1

MES hydrate Biotechnology Performance Certified, plant cell culture tested, ≥99.5%

5.5 - 6.7

4432-31-9 (anhydrous)

6.1

MES potassium salt

5.5 - 6.7

6.1

MES sodium salt ≥99% (titration)

5.5 - 6.7

6.1

MES sodium salt ≥99% (titration)

5.5 - 6.7

6.1

MES sodium salt Biotechnology Performance Certified

5.5 - 6.7

6.1

MES solution Biotechnology Performance Certified, 1 M, cell culture tested

5.5 - 6.7

MES low moisture content, ≥99% (titration)

5.5 - 6.7

6.1

MOBS ≥99% (titration)

6.9 - 8.3
6.9 - 8.3

7.6

MOPS hemisodium salt ≥99% (titration)

6.5 - 7.9

7.2

MOPS hemisodium salt foil pouch

6.5 - 7.9

7.2

MOPS sodium salt ≥99.5% (titration)

6.5 - 7.9

7.2

MOPS sodium salt Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)

6.5 - 7.9

7.2

MOPS sodium salt SigmaUltra, ≥99.5% anhydrous basis (titration)

6.5 - 7.9

7.2

MOPS solution Biotechnology Performance Certified, cell culture tested, 1 M

6.5 - 7.9

MOPS ≥99.5% (titration)

6.5 - 7.9

7.2

MOPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)

6.5 - 7.9

7.2

MOPSO sodium salt ≥99% (titration)

6.2 - 7.6

6.9

MOPSO sodium salt SigmaUltra, pH 10.0-12.0 (20 °C, 1 M in H₂O), ≥99% (titration)

6.2 - 7.6

6.9

MOPSO ≥99% (titration)

6.2 - 7.6
6.2 - 7.6

6.9

MOPS SigmaUltra, >99.5% (titration)

6.5 - 7.9

7.2

PIPES dipotassium salt ≥99% (titration)

6.1 - 7.5

6.8

PIPES disodium salt ≥99% (titration)

6.1 - 7.5

6.8

PIPES sesquisodium salt ≥99% (titration)

6.1 - 7.5

6.8

PIPES sodium salt ≥99% (titration)

6.1 - 7.5

6.8

PIPES ≥99% (titration)

6.1 - 7.5

6.8

PIPES Biotechnology Performance Certified, cell culture tested, ≥99% (titration)

6.1 - 7.5

6.8

PIPES SigmaUltra, ≥99% (titration)

6.1 - 7.5

6.8

POPSO hydrate ≥99% (titration)

7.2 - 8.5

68189-43-5 (anhydrous)

7.8

POPSO hydrate SigmaUltra, ≥99% (titration)

7.2 - 8.5

68189-43-5 (anhydrous)

7.8

POPSO sesquisodium salt

7.2 - 8.5

7.8

TABS ≥99% (titration)

8.2 - 9.6
8.2 - 9.6

8.9

TAPS sodium salt ≥99% (titration)

7.7 - 9.1

8.4

TAPS sodium salt Biotechnology Performance Certified, cell culture tested, ≥99%

7.7 - 9.1

8.4

TAPS ≥99.5% (titration)

7.7 - 9.1

8.4

TAPS Biotechnology Performance Certified, cell culture tested, ≥99.5% (titration)

7.7 - 9.1

8.4

TAPSO sodium salt

7.0 - 8.2

7.6

TAPSO ≥99% (titration)

7.0 - 8.2

7.6

TAPSO Biotechnology Performance Certified, cell culture tested, ≥99% (titration)

7.0 - 8.2

7.6

TAPSO SigmaUltra, ≥99% (titration)

7.0 - 8.2

7.6

TAPS SigmaUltra, ≥99.5% (titration)

7.7 - 9.1

8.4

TES hemisodium salt

6.8 - 8.2

7.5

TES sodium salt ≥99% (titration)

6.8 - 8.2

7.5

TES ≥99% (titration)

6.8 - 8.2

7.5

TES Biotechnology Performance Certified, cell culture tested, ≥99% (titration)

6.8 - 8.2

7.5

TES SigmaUltra, >99.5% (titration)

6.8 - 8.2

7.5

TRIS buffered saline caplets (for 15 mL), pH 7.6

Tricine ≥99% (titration)

7.4 - 8.8

8.1

Tricine Biotechnology Performance Certified, 1 M in solution, cell culture tested, 0.2 μm filtered

7.4 - 8.8

8.1

Tricine Biotechnology Performance Certified, cell culture tested, ≥99% (titration)

7.4 - 8.8

8.1

Tricine SigmaUltra, pH 4.0-6.0 (20 °C, 1 M in H₂O), ≥99% (titration)

7.4 - 8.8

8.1

Trizma^® Buffer substance BioChemika, for fish-farming, pH 8.3

Trizma^® Buffer substance BioChemika, pH 7.2

Trizma^® Buffer substance BioChemika, pH 7.4

Trizma^® Buffer substance BioChemika, pH 7.5

Trizma^® Buffer substance BioChemika, pH 7.6

Trizma^® Buffer substance BioChemika, pH 7.7

Trizma^® Buffer substance BioChemika, pH 7.8

Trizma^® Buffer substance BioChemika, pH 8.0

Trizma^® Buffer substance BioChemika, pH 8.1

Trizma^® Buffer substance BioChemika, pH 8.3

Trizma^® Buffer substance BioChemika, pH 8.8

Trizma^® Buffer substance BioChemika, pH 9.0

Trizma^® Pre-Set Crystals FISH grade, Type 7.2-FT, pH 7.2

Trizma^® Pre-Set Crystals Type 7.4-FT, FISH grade, pH 7.4

Trizma^® Pre-Set crystals FISH grade, Type 8.3-FT, pH 8.3

Trizma^® Pre-set crystals pH 7.0, average M_w 154.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.0, average M_w 154.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.2, average M_w 153.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.2, average M_w 153.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.4, average M_w 151.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.4, average M_w 151.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.5, average M_w 150.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.5, average M_w 150.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.6, average M_w 149.0

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.6, average M_w 149.0

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.7, average M_w 147.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.7, average M_w 147.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 7.8, average M_w 145.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.0, average M_w 141.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.0, average M_w 141.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.1

Trizma^® Pre-set crystals pH 8.1, average M_w 139.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.1, average M_w 139.8

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.3, average M_w 135.4

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.3, average M_w 135.4

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.5, average M_w 131.4

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.5, average M_w 131.4

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.8, average M_w 127.2

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.8, average M_w 127.2

7.0 - 9.0

Trizma^® Pre-set crystals pH 8.9, average M_w 125.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 9.0, average M_w 124.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 9.0, average M_w 124.6

7.0 - 9.0

Trizma^® Pre-set crystals pH 9.1, average M_w 123.0

7.0 - 9.0

Trizma^® base Biotechnology Performance Certified, meets EP, USP testing specifications, cell culture tested, ≥99.9% (titration)

7 - 9

8.1

Trizma^® base Primary Standard and Buffer, ≥99.9% (titration), crystalline

7 - 9
7 - 9

8.1

Trizma^® base SigmaUltra, pH 10.5-12.0 (20 °C, 1 M in H₂O), ≥99.9% (titration)

7 - 9

8.1

Trizma^® base crystalline

7 - 9

8.1

Trizma^® base puriss. p.a., ≥99.7% (T)

7 - 9

8.1

Trizma^® hydrochloride buffer solution pH 7.0, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.2, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.4, 0.1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.4, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.5, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.5, 2 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.6, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 7.8, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 8.0, 1 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 8.0, 2 M

7.0 - 9.0

Trizma^® hydrochloride buffer solution pH 9.0, 1 M

7.0 - 9.0

Trizma^® hydrochloride for molecular biology, Biotechnology Performance Certified, cell culture tested, ≥99.0% (titration)

7.0 - 9.0

8.1

Trizma^® hydrochloride pH 3.5-5.0 (20 °C, 0.5 M in H₂O), SigmaUltra, ≥99.0% (titration)

7.0 - 9.0

8.1

Trizma^® hydrochloride reagent grade, ≥99.0% (redox titration), crystalline

7.0 - 9.0

8.1

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