PEPscreen^® Peptides

Sigma-Genosys has developed a proprietary custom peptide synthesis platform utilizing Fmoc chemistry, providing a solution to enhance peptide screening applications. Large numbers of peptides, in 96-well arrays, are delivered quickly and affordably. MALDI-TOF mass spec is performed on 100% of the samples. Product Specifications Internal Testing of Synthesis Platform Technical Resources Application Data Share your expertise

PEPscreen® Library Design Tool

Product Specifications:

• Low cost per peptide
• Yield: ~0.5-2mg
• Length: 2-20 amino acids
• Comprehensive Modification Offering
• MALDI-ToF Mass Spectrometry on 100% of peptides
• Peptides supplied dried and in 96-well tube rack format
• Dispatch: approximately 7 business days
• Minimum order size is 24 peptides

Internal Testing of Synthesis Platform:

• We routinely run tests of this platform to ensure the quality of the product.
  
• Average Crude Purity of 10mers: ~86%
  
• Average Crude Purity of 15mers: ~73%
  
• Average Crude Purity of 20mers: ~61%
  
• Purity of ACP peptide at different positions on a 96-well plate: ~92% +/- 2%

Technical Resources:

• Epitope Mapping and Vaccine Research: Vaccination as a Strategic Medical Option
• Frequently Asked Questions for PEPscreen^® Peptides
• Generalized Steps of the ELISPOT Assay Procedure
• Guidelines for Dissolving PEPscreen® Peptide Sets (97 Kb PDF)
• Storage and Handling Guidelines (305 Kb PDF)

Application Data Now Available!
The following application data was received from customers using our PEPscreen Technology:

• Diverse CD4 Response to Vaccinia Virus in Human is Revealed by Proteome-Wide T cell Profiling (595 Kb PDF)
• Binding and Kinetic Analysis of Protein Interactions Probed by Label-Free SpotMatrix SPR Technology in a Peptide Chip Format
  (300 Kb PDF)
• Cross-CladeCD8+ T-Cell Responses With a Preference for the Predominant Circulating Clade (120 Kb PDF)
• Development of Peptide-based Microarrays for Screening Antibodies from Patients with Autoimmune Diseases (119 Kb PDF)
• High-throughput Screening of Peptide Substrates for Tyrosine Kinases Using PEPscreen® Custom Peptide Library (476 Kb PDF)
• Preservation of antimicrobial properties of complement peptide C3a - from invertebrates to humans
• Use of PEPscreen Libraries to Identify CD8 Epitopes Presented During Malaria Infection (138 Kb PDF)
• Use of PEPscreen Peptides to Investigate CTL Class I MHC and Th Class II Responses to AAV-hF.IX Gene Therapy (151 Kb PDF)

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