Epigenetics

DNA Methylation Quantification


As part of the effort to provide a fully integrated Epigenetic workflow, Sigma provides reagents and kits for DNA Methylation detection and analysis. Methylation-Specific PCR may be performed using our line of JumpStart polymerases; Sigma also provides reagents for qPCR analysis of modified samples.


Methylation Specific PCR
Hot Start PCR
Sigma-Aldrich provides all the necessary reagents and enzymes required for Hot Start PCR reactions. Our JumpStart antibody effectively prevents non-specific binding while the JumpStart polymerases provide superior amplification.

For additional information visit the
Hot Start PCR page
qPCR Reagents
The Sigma-Aldrich qPCR product line includes capillary, probe, and SYBR® based qPCR products. All of these systems are compatible with a wide variety of instruments and optimized for superior results.

For additional information visit the
Quantitative PCR page


View Post-Reaction Clean-up Kits for purification of your methylation-specific PCR product.



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