Functional Genomics & RNAi

We provide leading functional genomics technologies including RNA interference (RNAi) tools for gene silencing (siRNA, shRNA, miRNA) and cutting-edge systems for gene editing and gene knockout. The MISSION^® siRNA products offer effective target gene knockdown with reduced off-target effects while the MISSION shRNA portfolio includes the highly-validated lentiviral-based shRNA libraries of The RNAi Consortium (). Our (ZFN) and ® gene editing and gene disruption technologies provide innovative solutions for eukaryotic and prokaryotic systems, respectively. With our innovative Functional Genomics & RNAi products, you can accelerate your discovery!

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Information & News

Sigma-Aldrich® Receives Award from Michael J. Fox Foundation to Develop Parkinson's Disease Research Models

New Sigma Advanced Genetic Engineering Labs Offers Research Community Unique Rodent Models Developed Using Exclusive Gene-Editing Technology

Sigma-Aldrich Introduces MISSION^® esiRNA for Low Cost, High Specificity Pooled RNAi Screening

Sigma-Aldrich Introduces MISSION^® LentiPlex™ Pooled shRNA Libraries to Enable Rapid Whole Genome Screening in Primary Cells, Stem Cells or Tumor Cells

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