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Product Catalog >  Functional Genomics and RNAi >  CompoZr™ Knockout ZFN Kits

CompoZr™ Knockout ZFN Kits



CompoZr™ Knockout ZFNs create targeted double strand breaks at a gene specific target locus. Through the cellular process of non-homologous end joining, this double strand break can result in modification of the DNA sequence and therefor create a functional knockout of the targeted gene. To provide the best chance of creating a functional gene knockout, CompoZr Knockout ZFNs are targeted to the first 2/3 of the coding region for the gene of interest.

CompoZr Knockout ZFNs are provided as two plasmids encoding for the gene specific zinc finger nuclease and 10 aliquots of mRNA encoding for the ZFN. Also included in the kit are custom-designed primers, that allow for determination of the rate of mutation and for screening of individual clones that have the desired mutational event, and positive control DNA that has been modified using the CompoZr Knockout ZFN.

All Zinc Finger Nucleases are sold under license from Sangamo Biosciences. For a copy of the Label License provided with purchase of CompoZr ZFNs, please visit the ZFN Label License page. CompoZr is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.

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CKOZFN1002CompoZr® Knockout ZFN Kit human ABL1 (NM_005157) New human ... ABL1(25)
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CKOZFN1003CompoZr® Knockout ZFN Kit human ADAM17 (NM_003183) New human ... ADAM17(6868)
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CKOZFN1147CompoZr® Knockout ZFN Kit human ADRB3 (NM_000025) New human ... ADRB3(155)
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CKOZFN1004CompoZr® Knockout ZFN Kit human AR (NM_000044) New human ... AR(367)
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CKOZFN1005CompoZr® Knockout ZFN Kit human BACE1 (NM_012104) New human ... BACE1(23621)
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CKOZFN1006CompoZr® Knockout ZFN Kit human BAX (NM_004324) New human ... BAX(581)
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CKOZFN1007CompoZr® Knockout ZFN Kit human BCL2 (NM_000633) New human ... BCL2(596)
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CKOZFN1008CompoZr® Knockout ZFN Kit human CBLB (NM_170662) New human ... CBLB(868)
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CKOZFN1009CompoZr® Knockout ZFN Kit human CDH1 (NM_004360) New human ... CDH1(999)
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CKOZFN1010CompoZr® Knockout ZFN Kit human CDKN1B (NM_004064) New human ... CDKN1B(1027)
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CKOZFN1011CompoZr® Knockout ZFN Kit human CFLAR (NM_003879) New human ... CFLAR(8837)
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CKOZFN1012CompoZr® Knockout ZFN Kit human CHEK1 (NM_001274) New human ... CHEK1(1111)
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CKOZFN1013CompoZr® Knockout ZFN Kit human CLTB (NM_001834) New human ... CLTB(1212)
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CKOZFN1014CompoZr® Knockout ZFN Kit human CSF1R (NM_005211) New human ... CSF1R(1436)
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CKOZFN1015CompoZr® Knockout ZFN Kit human CSNK1E (NM_001894) New human ... CSNK1E(1454)
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CKOZFN1016CompoZr® Knockout ZFN Kit human CXCR4 (NM_003467) New human ... CXCR4(7852)
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CKOZFN1017CompoZr® Knockout ZFN Kit human DNM1 (NM_004408) New human ... DNM1(1759)
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CKOZFN1018CompoZr® Knockout ZFN Kit human EPAS1 (NM_001430) New human ... EPAS1(2034)
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CKOZFN1019CompoZr® Knockout ZFN Kit human EPHB3 (NM_004443) New human ... EPHB3(2049)
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CKOZFN1020CompoZr® Knockout ZFN Kit human ERBB2 (NM_004448) New human ... ERBB2(2064)
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CKOZFN1021CompoZr® Knockout ZFN Kit human ESR2 (NM_001437) New human ... ESR2(2100)
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CKOZFN1022CompoZr® Knockout ZFN Kit human FKBP8 (NM_012181) New human ... FKBP8(23770)
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CKOZFN1023CompoZr® Knockout ZFN Kit human FLT4 (NM_002020) New human ... FLT4(2324)
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CKOZFN1024CompoZr® Knockout ZFN Kit human GSK3B (NM_002093) New human ... GSK3B(2932)
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CKOZFN1025CompoZr® Knockout ZFN Kit human HDAC2 (NM_001527) New human ... HDAC2(3066)
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CKOZFN1026CompoZr® Knockout ZFN Kit human HIF1A (NM_001530) New human ... HIF1A(3091)
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CKOZFN1027CompoZr® Knockout ZFN Kit human IKBKB (NM_001556) New human ... IKBKB(3551)
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CKOZFN1028CompoZr® Knockout ZFN Kit human INPP4B (NM_003866) New human ... INPP4B(8821)
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CKOZFN1029CompoZr® Knockout ZFN Kit human ITGAV (NM_002210) New human ... ITGAV(3685)
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CKOZFN1030CompoZr® Knockout ZFN Kit human ITGB1 (NM_002211) New human ... ITGB1(3688)
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CKOZFN1031CompoZr® Knockout ZFN Kit human ITGB3 (NM_000212) New human ... ITGB3(3690)
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CKOZFN1032CompoZr® Knockout ZFN Kit human JUN (NM_002228) New human ... JUN(3725)
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CKOZFN1033CompoZr® Knockout ZFN Kit human KDR (NM_002253) New human ... KDR(3791)
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CKOZFN1034CompoZr® Knockout ZFN Kit human KIAA1303 (NM_020761) New human ... KIAA1303(57521)
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CKOZFN1035CompoZr® Knockout ZFN Kit human LRP1 (NM_002332) New human ... LRP1(4035)
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CKOZFN1036CompoZr® Knockout ZFN Kit human MAGI1 (NM_004742) New human ... MAGI1(9223)
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CKOZFN1037CompoZr® Knockout ZFN Kit human MAP3K5 (NM_005923) New human ... MAP3K5(4217)
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CKOZFN1038CompoZr® Knockout ZFN Kit human MMP14 (NM_004995) New human ... MMP14(4323)
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CKOZFN1039CompoZr® Knockout ZFN Kit human MMP2 (NM_004530) New human ... MMP2(4313)
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CKOZFN1040CompoZr® Knockout ZFN Kit human MMP9 (NM_004994) New human ... MMP9(4318)
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CKOZFN1041CompoZr® Knockout ZFN Kit human MYC (NM_002467) New human ... MYC(4609)
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CKOZFN1042CompoZr® Knockout ZFN Kit human NFATC4 (NM_004554) New human ... NFATC4(4776)
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CKOZFN1043CompoZr® Knockout ZFN Kit human NFE2L2 (NM_006164) New human ... NFE2L2(4780)
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CKOZFN1044CompoZr® Knockout ZFN Kit human NFKB1 (NM_003998) New human ... NFKB1(4790)
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CKOZFN1045CompoZr® Knockout ZFN Kit human NR1H3 (NM_005693) New human ... NR1H3(10062)
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CKOZFN1046CompoZr® Knockout ZFN Kit human PDK1 (NM_002610) New human ... PDK1(5163)
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CKOZFN1047CompoZr® Knockout ZFN Kit human PHLPP (NM_194449) New human ... PHLPP(23239)
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CKOZFN1048CompoZr® Knockout ZFN Kit human PIK3CB (NM_006219) New human ... PIK3CB(5291)
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CKOZFN1049CompoZr® Knockout ZFN Kit human PIM1 (NM_002648) New human ... PIM1(5292)
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CKOZFN1050CompoZr® Knockout ZFN Kit human PITX3 (NM_005029) New human ... PITX3(5309)
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CKOZFN1051CompoZr® Knockout ZFN Kit human PLK1 (NM_005030) New human ... PLK1(5347)
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CKOZFN1052CompoZr® Knockout ZFN Kit human PPARA (NM_005036) New human ... PPARA(5465)
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CKOZFN1053CompoZr® Knockout ZFN Kit human PPP2CA (NM_002715) New human ... PPP2CA(5515)
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CKOZFN1054CompoZr® Knockout ZFN Kit human PRKAA1 (NM_006251) New human ... PRKAA1(5562)
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CKOZFN1055CompoZr® Knockout ZFN Kit human PRKCA (NM_002737) New human ... PRKCA(5578)
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CKOZFN1056CompoZr® Knockout ZFN Kit human PRKCH (NM_006255) New human ... PRKCH(5583)
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CKOZFN1057CompoZr® Knockout ZFN Kit human PRKCZ (NM_002744) New human ... PRKCZ(5590)
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CKOZFN1058CompoZr® Knockout ZFN Kit human PRMT1 (NM_001536) New human ... PRMT1(3276)
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CKOZFN1059CompoZr® Knockout ZFN Kit human PTBP1 (NM_002819) New human ... PTBP1(5725)
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CKOZFN1060CompoZr® Knockout ZFN Kit human PTK2 (NM_005607) New human ... PTK2(5747)
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CKOZFN1061CompoZr® Knockout ZFN Kit human PTPN6 (NM_002831) New human ... PTPN6(5777)
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CKOZFN1062CompoZr® Knockout ZFN Kit human RAPGEF3 (NM_006105) New human ... RAPGEF3(10411)
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CKOZFN1063CompoZr® Knockout ZFN Kit human RB1 (NM_000321) New human ... RB1(5925)
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CKOZFN1064CompoZr® Knockout ZFN Kit human RET (NM_020630) New human ... RET(5979)
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CKOZFN1065CompoZr® Knockout ZFN Kit human RICTOR (NM_152756) New human ... RICTOR(253260)
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CKOZFN1066CompoZr® Knockout ZFN Kit human RIPK1 (NM_003804) New human ... RIPK1(8737)
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CKOZFN1067CompoZr® Knockout ZFN Kit human ROCK1 (NM_005406) New human ... ROCK1(6093)
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CKOZFN1068CompoZr® Knockout ZFN Kit human SH3YL1 (NM_015677) New human ... SH3YL1(26751)
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CKOZFN1069CompoZr® Knockout ZFN Kit human SLIT2 (NM_004787) New human ... SLIT2(9353)
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CKOZFN1070CompoZr® Knockout ZFN Kit human SMAD4 (NM_005359) New human ... SMAD4(4089)
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CKOZFN1071CompoZr® Knockout ZFN Kit human STAT3 (NM_003150) New human ... STAT3(6774)
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CKOZFN1072CompoZr® Knockout ZFN Kit human SYK (NM_003177) New human ... SYK(6850)
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CKOZFN1001CompoZr® Knockout ZFN Kit human TP53 (NM_000546) New human ... TP53(7157)
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CKOZFN1073CompoZr® Knockout ZFN Kit human TSC1 (NM_000368) New human ... TSC1(7248)
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CKOZFN1074CompoZr® Knockout ZFN Kit human TSC2 (NM_000548) New human ... TSC2(7249)
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CKOZFN1075CompoZr® Knockout ZFN Kit human VAV1 (NM_005428) New human ... VAV1(7409)
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CKOZFN1076CompoZr® Knockout ZFN Kit human VCAN (NM_004385) New human ... VCAN(1462)
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CKOZFN1077CompoZr® Knockout ZFN Kit human VEGFC (NM_005429) New human ... VEGFC(7424)
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