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Product Catalog >  Functional Genomics and RNAi >  CompoZr™ Knockout ZFN Kits

CompoZr™ Knockout ZFN Kits



CompoZr™ Knockout ZFNs create targeted double strand breaks at a gene specific target locus. Through the cellular process of non-homologous end joining, this double strand break can result in modification of the DNA sequence and therefor create a functional knockout of the targeted gene. To provide the best chance of creating a functional gene knockout, CompoZr Knockout ZFNs are targeted to the first 2/3 of the coding region for the gene of interest.

CompoZr Knockout ZFNs are provided as two plasmids encoding for the gene specific zinc finger nuclease and 10 aliquots of mRNA encoding for the ZFN. Also included in the kit are custom-designed primers, that allow for determination of the rate of mutation and for screening of individual clones that have the desired mutational event, and positive control DNA that has been modified using the CompoZr Knockout ZFN.

All Zinc Finger Nucleases are sold under license from Sangamo Biosciences. For a copy of the Label License provided with purchase of CompoZr ZFNs, please visit the ZFN Label License page. CompoZr is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.

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CKOZFN1105CompoZr Knockout ZFN Kit human ABCA1 (NM_005502) New human ... ABCA1(19)
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CKOZFN1002CompoZr Knockout ZFN Kit human ABL1 (NM_005157) New human ... ABL1(25)
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CKOZFN1154CompoZr Knockout ZFN Kit human ACE2 (NM_021804) New human ... ACE2(59272)
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CKOZFN1003CompoZr Knockout ZFN Kit human ADAM17 (NM_003183) New human ... ADAM17(6868)
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CKOZFN1147CompoZr Knockout ZFN Kit human ADRB3 (NM_000025) New human ... ADRB3(155)
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CKOZFN1148CompoZr Knockout ZFN Kit human ADRB3 (NM_000025) New human ... ADRB3(155)
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CKOZFN1153CompoZr Knockout ZFN Kit human AGTRAP (NM_020350) New human ... AGTRAP(57085)
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CKOZFN1152CompoZr Knockout ZFN Kit human AGTRAP (NM_020350) New human ... AGTRAP(57085)
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CKOZFN1004CompoZr Knockout ZFN Kit human AR (NM_000044) New human ... AR(367)
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CKOZFN1117CompoZr Knockout ZFN Kit human ASNS (NM_001673) New human ... ASNS(440)
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CKOZFN1136CompoZr Knockout ZFN Kit human AURKB (NM_004217) New human ... AURKB(9212)
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CKOZFN1079CompoZr Knockout ZFN Kit human AVPR2 (NM_000054) New human ... AVPR2(554)
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CKOZFN1078CompoZr Knockout ZFN Kit human AVPR2 (NM_000054) New human ... AVPR2(554)
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CKOZFN1005CompoZr Knockout ZFN Kit human BACE1 (NM_012104) New human ... BACE1(23621)
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CKOZFN1006CompoZr Knockout ZFN Kit human BAX (NM_004324) New human ... BAX(581)
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CKOZFN1007CompoZr Knockout ZFN Kit human BCL2 (NM_000633) New human ... BCL2(596)
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CKOZFN1112CompoZr Knockout ZFN Kit human BMP4 (NM_001202) New human ... BMP4(652)
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CKOZFN1111CompoZr Knockout ZFN Kit human BMP4 (NM_001202) New human ... BMP4(652)
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CKOZFN1132CompoZr Knockout ZFN Kit human CACNA2D4 (NM_172364) New human ... CACNA2D4(93589)
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CKOZFN1008CompoZr Knockout ZFN Kit human CBLB (NM_170662) New human ... CBLB(868)
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CKOZFN1164CompoZr Knockout ZFN Kit human CCR5 (NM_000579) New human ... CCR5(1234)
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CKOZFN1120CompoZr Knockout ZFN Kit human CD19 (NM_001770) New human ... CD19(930)
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CKOZFN1121CompoZr Knockout ZFN Kit human CD33 (NM_001772) New human ... CD33(945)
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CKOZFN1173CompoZr Knockout ZFN Kit human CD34 (NM_001025109) New human ... CD34(947)
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CKOZFN1122CompoZr Knockout ZFN Kit human CD38 (NM_001775) New human ... CD38(952)
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CKOZFN1113CompoZr Knockout ZFN Kit human CD40 (NM_001250) New human ... CD40(958)
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CKOZFN1124CompoZr Knockout ZFN Kit human CD52 (NM_001803) New human ... CD52(1043)
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CKOZFN1119CompoZr Knockout ZFN Kit human CD8A (NM_001768) New human ... CD8A(925)
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CKOZFN1118CompoZr Knockout ZFN Kit human CD8A (NM_001768) New human ... CD8A(925)
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CKOZFN1131CompoZr Knockout ZFN Kit human CDCP1 (NM_022842) New human ... CDCP1(64866)
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CKOZFN1009CompoZr Knockout ZFN Kit human CDH1 (NM_004360) New human ... CDH1(999)
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CKOZFN1123CompoZr Knockout ZFN Kit human CDK2 (NM_001798) New human ... CDK2(1017)
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CKOZFN1010CompoZr Knockout ZFN Kit human CDKN1B (NM_004064) New human ... CDKN1B(1027)
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CKOZFN1167CompoZr Knockout ZFN Kit human CDKN2A (NM_000077) New human ... CDKN2A(1029)
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CKOZFN1080CompoZr Knockout ZFN Kit human CETP (NM_000078) New human ... CETP(1071)
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CKOZFN1011CompoZr Knockout ZFN Kit human CFLAR (NM_003879) New human ... CFLAR(8837)
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CKOZFN1161CompoZr Knockout ZFN Kit human CFTR (NM_000492) New human ... CFTR(1080)
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CKOZFN1012CompoZr Knockout ZFN Kit human CHEK1 (NM_001274) New human ... CHEK1(1111)
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CKOZFN1013CompoZr Knockout ZFN Kit human CLTB (NM_001834) New human ... CLTB(1212)
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CKOZFN1126CompoZr Knockout ZFN Kit human CLU (NM_001831) New human ... CLU(1191)
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CKOZFN1150CompoZr Knockout ZFN Kit human CNR1 (NM_016083) New human ... CNR1(1268)
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CKOZFN1149CompoZr Knockout ZFN Kit human CNR1 (NM_016083) New human ... CNR1(1268)
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CKOZFN1014CompoZr Knockout ZFN Kit human CSF1R (NM_005211) New human ... CSF1R(1436)
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CKOZFN1084CompoZr Knockout ZFN Kit human CSF3 (NM_000759) New human ... CSF3(1440)
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CKOZFN1015CompoZr Knockout ZFN Kit human CSNK1E (NM_001894) New human ... CSNK1E(1454)
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CKOZFN1158CompoZr Knockout ZFN Kit human CSNK2A1 (NM_001895) New human ... CSNK2A1(1457)
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CKOZFN1165CompoZr Knockout ZFN Kit human CXCR4 (NM_001008540) New human ... CXCR4(7852)
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CKOZFN1016CompoZr Knockout ZFN Kit human CXCR4 (NM_003467) New human ... CXCR4(7852)
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CKOZFN1156CompoZr Knockout ZFN Kit human DGCR8 (NM_022720) New human ... DGCR8(54487)
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CKOZFN1155CompoZr Knockout ZFN Kit human DGCR8 (NM_022720) New human ... DGCR8(54487)
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CKOZFN1085CompoZr Knockout ZFN Kit human DHFR (NM_000791) New human ... DHFR(1719)
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CKOZFN1172CompoZr Knockout ZFN Kit human DICER (NM_030621) New human ... DICER(23405)
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CKOZFN1146CompoZr Knockout ZFN Kit human DKK1 (NM_012242) New human ... DKK1(22943)
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CKOZFN1145CompoZr Knockout ZFN Kit human DKK1 (NM_012242) New human ... DKK1(22943)
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CKOZFN1144CompoZr Knockout ZFN Kit human DKK1 (NM_012242) New human ... DKK1(22943)
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CKOZFN1017CompoZr Knockout ZFN Kit human DNM1 (NM_004408) New human ... DNM1(1759)
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CKOZFN1101CompoZr Knockout ZFN Kit human DRD2 (NM_000795) New human ... DRD2(1813)
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CKOZFN1130CompoZr Knockout ZFN Kit human EIF2AK2 (NM_002759) New human ... EIF2AK2(5610)
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CKOZFN1018CompoZr Knockout ZFN Kit human EPAS1 (NM_001430) New human ... EPAS1(2034)
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CKOZFN1138CompoZr Knockout ZFN Kit human EPHB2 (NM_004442) New human ... EPHB2(2048)
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CKOZFN1019CompoZr Knockout ZFN Kit human EPHB3 (NM_004443) New human ... EPHB3(2049)
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CKOZFN1103CompoZr Knockout ZFN Kit human EPO (NM_000799) New human ... EPO(2056)
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CKOZFN1102CompoZr Knockout ZFN Kit human EPO (NM_000799) New human ... EPO(2056)
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CKOZFN1020CompoZr Knockout ZFN Kit human ERBB2 (NM_004448) New human ... ERBB2(2064)
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CKOZFN1163CompoZr Knockout ZFN Kit human ESR1 (NM_000125) New human ... ESR1(2099)
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CKOZFN1021CompoZr Knockout ZFN Kit human ESR2 (NM_001437) New human ... ESR2(2100)
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CKOZFN1096CompoZr Knockout ZFN Kit human F2 (NM_000506) New human ... F2(2147)
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CKOZFN1127CompoZr Knockout ZFN Kit human F2R (NM_001992) New human ... F2R(2149)
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CKOZFN1128CompoZr Knockout ZFN Kit human F2R (NM_001992) New human ... F2R(2149)
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CKOZFN1081CompoZr Knockout ZFN Kit human F5 (NM_000130) New human ... F5(2153)
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CKOZFN1134CompoZr Knockout ZFN Kit human FDXR (NM_004110) New human ... FDXR(2232)
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CKOZFN1135CompoZr Knockout ZFN Kit human FDXR (NM_004110) New human ... FDXR(2232)
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CKOZFN1104CompoZr Knockout ZFN Kit human FFAR1 (NM_005303) New human ... FFAR1(2864)
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CKOZFN1022CompoZr Knockout ZFN Kit human FKBP8 (NM_012181) New human ... FKBP8(23770)
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CKOZFN1023CompoZr Knockout ZFN Kit human FLT4 (NM_002020) New human ... FLT4(2324)
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CKOZFN1082CompoZr Knockout ZFN Kit human GCK (NM_000162) New human ... GCK(2645)
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CKOZFN1170CompoZr Knockout ZFN Kit human GILZ (NM_001015881) New human ... GILZ(1831)
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CKOZFN1159CompoZr Knockout ZFN Kit human GLUL (NM_002065) New human ... GLUL(2752)
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CKOZFN1160CompoZr Knockout ZFN Kit human GLUL (NM_002065) New human ... GLUL(2752)
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CKOZFN1088CompoZr Knockout ZFN Kit human GNRHR (NM_000406) New human ... GNRHR(2798)
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CKOZFN1024CompoZr Knockout ZFN Kit human GSK3B (NM_002093) New human ... GSK3B(2932)
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CKOZFN1025CompoZr Knockout ZFN Kit human HDAC2 (NM_001527) New human ... HDAC2(3066)
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CKOZFN1140CompoZr Knockout ZFN Kit human HFE2 (NM_145277) New human ... HFE2(148738)
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CKOZFN1026CompoZr Knockout ZFN Kit human HIF1A (NM_001530) New human ... HIF1A(3091)
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CKOZFN1092CompoZr Knockout ZFN Kit human HRH1 (NM_000861) New human ... HRH1(3269)
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CKOZFN1093CompoZr Knockout ZFN Kit human HRH1 (NM_000861) New human ... HRH1(3269)
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CKOZFN1090CompoZr Knockout ZFN Kit human HSD17B1 (NM_000413) New human ... HSD17B1(3292)
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CKOZFN1089CompoZr Knockout ZFN Kit human HSD17B1 (NM_000413) New human ... HSD17B1(3292)
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CKOZFN1094CompoZr Knockout ZFN Kit human HTR1B (NM_000863) New human ... HTR1B(3351)
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CKOZFN1095CompoZr Knockout ZFN Kit human HTR1B (NM_000863) New human ... HTR1B(3351)
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CKOZFN1106CompoZr Knockout ZFN Kit human HTR3A (NM_000869) New human ... HTR3A(3359)
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CKOZFN1107CompoZr Knockout ZFN Kit human HTR6 (NM_000871) New human ... HTR6(3362)
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CKOZFN1099CompoZr Knockout ZFN Kit human IGF1 (NM_000618) New human ... IGF1(3479)
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CKOZFN1027CompoZr Knockout ZFN Kit human IKBKB (NM_001556) New human ... IKBKB(3551)
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CKOZFN1157CompoZr Knockout ZFN Kit human IL17RC (NM_032732) New human ... IL17RC(84818)
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CKOZFN1098CompoZr Knockout ZFN Kit human IL1B (NM_000576) New human ... IL1B(3553)
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CKOZFN1151CompoZr Knockout ZFN Kit human IL23A (NM_016584) New human ... IL23A(51561)
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CKOZFN1176CompoZr Knockout ZFN Kit human IL2Rg (NM_000206) New human ... IL2RG(3561)
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CKOZFN1091CompoZr Knockout ZFN Kit human IL4R (NM_000418) New human ... IL4R(3566)
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CKOZFN1097CompoZr Knockout ZFN Kit human IL6R (NM_000565) New human ... IL6R(3570)
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CKOZFN1028CompoZr Knockout ZFN Kit human INPP4B (NM_003866) New human ... INPP4B(8821)
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CKOZFN1114CompoZr Knockout ZFN Kit human IRAK1 (NM_001569) New human ... IRAK1(3654)
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CKOZFN1115CompoZr Knockout ZFN Kit human IRAK1 (NM_001569) New human ... IRAK1(3654)
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CKOZFN1108CompoZr Knockout ZFN Kit human ITGA4 (NM_000885) New human ... ITGA4(3676)
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CKOZFN1029CompoZr Knockout ZFN Kit human ITGAV (NM_002210) New human ... ITGAV(3685)
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CKOZFN1030CompoZr Knockout ZFN Kit human ITGB1 (NM_002211) New human ... ITGB1(3688)
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CKOZFN1031CompoZr Knockout ZFN Kit human ITGB3 (NM_000212) New human ... ITGB3(3690)
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CKOZFN1110CompoZr Knockout ZFN Kit human ITGB7 (NM_000889) New human ... ITGB7(3695)
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CKOZFN1109CompoZr Knockout ZFN Kit human ITGB7 (NM_000889) New human ... ITGB7(3695)
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CKOZFN1032CompoZr Knockout ZFN Kit human JUN (NM_002228) New human ... JUN(3725)
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CKOZFN1033CompoZr Knockout ZFN Kit human KDR (NM_002253) New human ... KDR(3791)
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CKOZFN1034CompoZr Knockout ZFN Kit human KIAA1303 (NM_020761) New human ... KIAA1303(57521)
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CKOZFN1035CompoZr Knockout ZFN Kit human LRP1 (NM_002332) New human ... LRP1(4035)
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CKOZFN1036CompoZr Knockout ZFN Kit human MAGI1 (NM_004742) New human ... MAGI1(9223)
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CKOZFN1037CompoZr Knockout ZFN Kit human MAP3K5 (NM_005923) New human ... MAP3K5(4217)
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CKOZFN1038CompoZr Knockout ZFN Kit human MMP14 (NM_004995) New human ... MMP14(4323)
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CKOZFN1039CompoZr Knockout ZFN Kit human MMP2 (NM_004530) New human ... MMP2(4313)
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CKOZFN1040CompoZr Knockout ZFN Kit human MMP9 (NM_004994) New human ... MMP9(4318)
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CKOZFN1100CompoZr Knockout ZFN Kit human MPO (NM_000250) New human ... MPO(4353)
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CKOZFN1169CompoZr Knockout ZFN Kit human MRP2 (NM_000392) New human ... MRP2(1244)
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CKOZFN1041CompoZr Knockout ZFN Kit human MYC (NM_002467) New human ... MYC(4609)
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CKOZFN1042CompoZr Knockout ZFN Kit human NFATC4 (NM_004554) New human ... NFATC4(4776)
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CKOZFN1043CompoZr Knockout ZFN Kit human NFE2L2 (NM_006164) New human ... NFE2L2(4780)
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CKOZFN1044CompoZr Knockout ZFN Kit human NFKB1 (NM_003998) New human ... NFKB1(4790)
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CKOZFN1162CompoZr Knockout ZFN Kit human NME1 (NM_000269) New human ... NME1(4830)
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CKOZFN1171CompoZr Knockout ZFN Kit human NOTCH1 (NM_017617) New human ... NOTCH1(4851)
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CKOZFN1045CompoZr Knockout ZFN Kit human NR1H3 (NM_005693) New human ... NR1H3(10062)
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CKOZFN1116CompoZr Knockout ZFN Kit human PARP1 (NM_001618) New human ... PARP1(142)
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CKOZFN1141CompoZr Knockout ZFN Kit human PDE4A (NM_006202) New human ... PDE4A(5141)
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CKOZFN1046CompoZr Knockout ZFN Kit human PDK1 (NM_002610) New human ... PDK1(5163)
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CKOZFN1174CompoZr Knockout ZFN Kit human PDX-1 (NM_000209) New human ... PDX-1(3651)
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CKOZFN1047CompoZr Knockout ZFN Kit human PHLPP (NM_194449) New human ... PHLPP(23239)
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CKOZFN1048CompoZr Knockout ZFN Kit human PIK3CB (NM_006219) New human ... PIK3CB(5291)
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CKOZFN1049CompoZr Knockout ZFN Kit human PIM1 (NM_002648) New human ... PIM1(5292)
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CKOZFN1050CompoZr Knockout ZFN Kit human PITX3 (NM_005029) New human ... PITX3(5309)
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CKOZFN1051CompoZr Knockout ZFN Kit human PLK1 (NM_005030) New human ... PLK1(5347)
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CKOZFN1086CompoZr Knockout ZFN Kit human PLXDC1 (NM_020405) New human ... PLXDC1(57125)
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CKOZFN1087CompoZr Knockout ZFN Kit human PLXDC1 (NM_020405) New human ... PLXDC1(57125)
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CKOZFN1052CompoZr Knockout ZFN Kit human PPARA (NM_005036) New human ... PPARA(5465)
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CKOZFN1139CompoZr Knockout ZFN Kit human PPARG (NM_005037) New human ... PPARG(5468)
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CKOZFN1053CompoZr Knockout ZFN Kit human PPP2CA (NM_002715) New human ... PPP2CA(5515)
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CKOZFN1054CompoZr Knockout ZFN Kit human PRKAA1 (NM_006251) New human ... PRKAA1(5562)
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CKOZFN1142CompoZr Knockout ZFN Kit human PRKAB1 (NM_006253) New human ... PRKAB1(5564)
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CKOZFN1055CompoZr Knockout ZFN Kit human PRKCA (NM_002737) New human ... PRKCA(5578)
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CKOZFN1133CompoZr Knockout ZFN Kit human PRKCD (NM_006254) New human ... PRKCD(5580)
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CKOZFN1056CompoZr Knockout ZFN Kit human PRKCH (NM_006255) New human ... PRKCH(5583)
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CKOZFN1057CompoZr Knockout ZFN Kit human PRKCZ (NM_002744) New human ... PRKCZ(5590)
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CKOZFN1058CompoZr Knockout ZFN Kit human PRMT1 (NM_001536) New human ... PRMT1(3276)
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CKOZFN1059CompoZr Knockout ZFN Kit human PTBP1 (NM_002819) New human ... PTBP1(5725)
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CKOZFN1166CompoZr Knockout ZFN Kit human PTEN (NM_000314) New human ... PTEN(5728)
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CKOZFN1060CompoZr Knockout ZFN Kit human PTK2 (NM_005607) New human ... PTK2(5747)
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CKOZFN1061CompoZr Knockout ZFN Kit human PTPN6 (NM_002831) New human ... PTPN6(5777)
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CKOZFN1062CompoZr Knockout ZFN Kit human RAPGEF3 (NM_006105) New human ... RAPGEF3(10411)
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CKOZFN1063CompoZr Knockout ZFN Kit human RB1 (NM_000321) New human ... RB1(5925)
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CKOZFN1064CompoZr Knockout ZFN Kit human RET (NM_020630) New human ... RET(5979)
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CKOZFN1065CompoZr Knockout ZFN Kit human RICTOR (NM_152756) New human ... RICTOR(253260)
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CKOZFN1066CompoZr Knockout ZFN Kit human RIPK1 (NM_003804) New human ... RIPK1(8737)
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CKOZFN1067CompoZr Knockout ZFN Kit human ROCK1 (NM_005406) New human ... ROCK1(6093)
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CKOZFN1129CompoZr Knockout ZFN Kit human SERPINF1 (NM_002615) New human ... SERPINF1(5176)
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CKOZFN1068CompoZr Knockout ZFN Kit human SH3YL1 (NM_015677) New human ... SH3YL1(26751)
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CKOZFN1083CompoZr Knockout ZFN Kit human SHH (NM_000193) New human ... SHH(6469)
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CKOZFN1143CompoZr Knockout ZFN Kit human SIRT2 (NM_012237) New human ... SIRT2(22933)
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CKOZFN1125CompoZr Knockout ZFN Kit human SLC6A7 (NM_014228) New human ... SLC6A7(6534)
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CKOZFN1069CompoZr Knockout ZFN Kit human SLIT2 (NM_004787) New human ... SLIT2(9353)
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CKOZFN1070CompoZr Knockout ZFN Kit human SMAD4 (NM_005359) New human ... SMAD4(4089)
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CKOZFN1071CompoZr Knockout ZFN Kit human STAT3 (NM_003150) New human ... STAT3(6774)
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CKOZFN1072CompoZr Knockout ZFN Kit human SYK (NM_003177) New human ... SYK(6850)
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CKOZFN1137CompoZr Knockout ZFN Kit human TNFRSF10A (NM_003844) New human ... TNFRSF10A(8797)
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CKOZFN1001CompoZr Knockout ZFN Kit human TP53 (NM_000546) New human ... TP53(7157)
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CKOZFN1073CompoZr Knockout ZFN Kit human TSC1 (NM_000368) New human ... TSC1(7248)
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CKOZFN1074CompoZr Knockout ZFN Kit human TSC2 (NM_000548) New human ... TSC2(7249)
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CKOZFN1168CompoZr Knockout ZFN Kit human TWIST1 (NM_000474) New human ... TWIST1(7291)
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CKOZFN1075CompoZr Knockout ZFN Kit human VAV1 (NM_005428) New human ... VAV1(7409)
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CKOZFN1076CompoZr Knockout ZFN Kit human VCAN (NM_004385) New human ... VCAN(1462)
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CKOZFN1077CompoZr Knockout ZFN Kit human VEGFC (NM_005429) New human ... VEGFC(7424)
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CKOZFN1175CompoZr Knockout ZFN Kit human WAS (NM_000377) New human ... WAS(7454)
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