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RNAi FAQs

Experimental Design and Analysis

What is an in vivo experiment?  What is an ex vivo experiment?
In vivo refers to within the living, i.e. in a test subject (mouse, rat, etc.).  Ex vivo refers to experimentation done in tissue in an artificial environment outside the organism with minimum alteration of natural conditions.  In vitro is outside the living organism.

What is the correlation between mRNA knockdown and protein knockdown?
Generally, mRNA knockdown and protein knockdown are related.  However, the protein knockdown can be more muted than the mRNA.

For additional questions regarding our siRNA and shRNA product lines, please select one of the links below:

shRNA FAQs