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Life Science > Functional Genomics & RNAi > shRNA
Functional Genomics & RNAi

shRNA

When you partner with Sigma's MISSION® RNAi team, you gain access to the extensively validated genome-wide TRC shRNA library, ideal screening formats, and flexible lentiviral shRNA custom services designed to accelerate your RNAi discovery. Save time and resources when you take advantage of the MISSION team's world-class expertise in high-throughput lentiviral manufacturing and the collection of phase two validation data (TRC2) from the Broad Institute, The RNAi Consortium (TRC) and Sigma®.

As a collaborative member and distributor of TRC1 and TRC2, Sigma offers multiple formats of the TRC1 lentivirus-based shRNA library consisting of over 150,000 pre-cloned shRNA vectors targeting more than 15,000 human and 15,000 mouse genes (TRC2 clone content expansion in process). Whole-genome TRC shRNA libraries, individual RNAi clones/vectors, or shRNA gene family sets (gene panels) are available in the standard glycerol format as well as the higher quality DNA and lentiviral formats exclusively from Sigma. shRNAs targeting your specific human and mouse genes of interest can be located through the Your Favorite Gene search engine.


Search for shRNA clones


Products:
  • Product Overview
  • shRNA Screening (Libraries and Gene Family Sets)
  • Single Genes and Clones
  • Controls
  • High Titer Lentivirus
  • Custom shRNA Cloning (GFP, etc.)
  • Custom Capabilities
  • Lentiviral Packaging Mix
  • ExpressMag® Delivery Enhancer
  • New Products
  • Online Product Catalog

Academic Programs:
  • Academic Program
  • Functional Genomics Partnership Program

Special Offers:
  • RNAi Workshops
  • MISSION® Promotions 
 

Learning Center:
  • TRC1 and TRC2 shRNA Library Introduction
  • Getting Started
  • Technical Bulletins
  • Vector Maps 
  • In vivo shRNA & Lentiviral Solutions
  • Protocols
  • Application Data
  • FAQ Center
  • TRC Library Citations
  • RNAi and Lentiviral Publications
  • Additional shRNA and RNAi Resources
  • Press Releases
  • MISSION® Label License

Tool Box:
  • Your Favorite Gene Search
  • RNAi Workflow
  • NCBI/HGNC/MGI Links
 
 
Related Topics:
  • siRNA
  • ZFN Gene Knockout
  • RNAi Books
  • Core Bioreagents
  • Labware
 
 
Information & News
 

Sigma-Aldrich® Introduces MISSION LentiPlex™ Pooled shRNA Libraries to Enable Rapid Whole Genome Screening in Primary Cells, Stem Cells or Tumor Cells


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LentiExpress is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.
ExpressMag is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.

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