|
Our comprehensive shRNA product offering currently consists of over 159,000 pre-cloned shRNA constructs targeting more than 16,000 human and 15,950 mouse genes. Each gene is represented by a multiple vector constructs targeting different regions of the gene sequence. Each shRNA is cloned into the pLKO.1 lentiviral vector and each construct is sequence verified to ensure a match to the target gene. The individual clones are available in frozen bacterial glycerol stock format, purified plasmid DNA format, or lentiviral transduction particle format.
Enter your favorite gene in the search box below.  We've made ordering MISSION shRNA clones easy through Sigma's state-of-the-art web interface, Your Favorite Gene.
 Search for Your Favorite Gene Locate shRNA clones for your specific gene of interest through Your Favorite Gene (YFG) Search. To search YFG for shRNA targets, enter the gene name, symbol, alternate symbol, homologs, accession number, RefSeq, TRC number or gene ID number in the search box and look for shRNA links in the results. Genes with the red cube "validated" symbol designate validated clones that have been shown to have knockdown efficiencies of 70% or greater at the mRNA level in one or more cell lines. Sigma-Aldrich guarantees that upon purchase of the defined clone set quantity on the shRNA detail page for your gene of interest (this varies, but is typically 5 clones), that at least one of those clones for a gene should yield greater than 70% knockdown. Take the YFG Tour and see how it works first-hand. If you encounter any issues in running your search or have suggestions to improve YFG, please email us at yfgsuggestions@sial.com.
Contact Us For questions about the library, pricing and quotes or other concerns, please email us at: RNAi@sial.com. MISSION is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. Label License. |
|||||||||||
|
||||||||||||
