shRNA

Ordering and Pricing FAQs


MISSION shRNA

Can I order MISSION® shRNA clones over the phone?
Why don't the MISSION shRNA have product numbers?
How long will my order take to process?
Do I have to create a profile to order?
How do I create an online profile with order access?
Can I cancel my order?
Why can't I see the pricing for MISSION shRNA?
How do I inquire for special quotes and large order discounts?
Are there any MISSION products that do not have to be ordered online?
Can individual MISSION TRC shRNA constructs be purchased and in what format are they available?
Are there any additional costs to ship internationally?
How do I order high titer virus?
I ordered an shRNA target set in the past and found the best clone (TRCN), but then went back to your site to find all the TRCNs have changed? What's up with that?


Can I order MISSION shRNA clones over the phone?
Currently the best way to order is over the web. If you have a special situation or need assistance with your order, please visit our shRNA ordering help page, or email us at MISSIONRNAi@sial.com.


Why don't the MISSION shRNA have product numbers?
MISSION shRNA products are made on demand and do not have Sigma product numbers like our other products. The clone library currently consists of more than 200,000 different constructs. The online order process ensures that the information for each requested clone gets fed into our production system correctly.


How long will my order take to process?
Each order is produced on demand in our state-of-the-art manufacturing facility. The following times are required to produce each format after the order appears in our LIMS manufacturing database:

SHCLNG – Bacterial Stock   48 hours
SHCLND – Purified DNA   3 weeks
SHCLNV – Lentiviral Transduction Particles   4 weeks

Orders ship Monday through Thursday. Glycerol format orders received after 2 pm on Wednesday may not ship until the following Monday. Some orders may require additional time to process. Please allow up to 2 weeks additional shipping time for international orders.

Please note:
If your order includes customization of volume, titer, or vector, the turn-around-time will be longer than listed above.

Additionally, if your order contains >25 individual clones with vector customization, or >50 individual clones in the standard vector, the turn-around-time will be longer than listed here. We recommend contacting your local sales representative for pricing and timelines for larger orders.

Do I have to create a profile to order?
Yes, please create an online profile and request order access (one time step that takes 24-48 hours for approval). If you are not registered on Sigma's website, click here (401 Kb PDF) for a guide to registering.


How do I create an online profile with order access?
For a guide to creating an online profile on Sigma's website, click here (401 Kb PDF).

Can I cancel my order?
MISSION shRNA products are only created once an order is verified. Once your order has been processed it cannot be cancelled.


Why can’t I see the pricing for MISSION shRNA?
You need to be registered in order to see the prices. For a guide to creating an online profile on Sigma's website, click here (401 Kb PDF).


How do I inquire for special quotes and large order discounts?
Please contact your local sales representative or email us at MISSIONRNAi@sial.com for more information.


Are there any MISSION products that do not have to be ordered online?
The Gene family sets, LentiPlex™, and the Controls can be ordered either over the phone or online, but feel free to contact your local sales representative or email us at MISSIONRNAi@sial.com with any questions.


Can individual MISSION TRC shRNA constructs be purchased and in what format are they available?
Individual clones may be purchased in any of the three available formats: bacterial stock, purified DNA and Lentiviral transduction particles. Discounts apply when buying multiple clones for a single RefSeq. Log in and visit the ordering page for your RefSeq of interest to see the minimum purchase requirements for discounting.

Are there any additional costs to ship internationally?
Please contact your local sales representative about any unique pricing questions for your area.

How do I order high titer virus?
First, log into the Sigma website. High titer virus can easily be requested online by selecting the appropriate clone or clones for the RefSeq on the MISSION TRC Lentivirus ordering page and selecting the titer that is desired using the pulldown menu at the top of the clone listing on the Lentivirus page for your RefSeq of interest. Other modifications to Lentiviral orders are also available (custom volumes and custom vector backbones). If you do not see what you are looking for, contact your local sales representative.

I ordered an shRNA target set in the past and found the best clone (TRCN), but then went back to your site to find all the TRCNs have changed? What's up with that?
We are continually validating, and updating the TRC library we provide. In that vein, we often prioritize the most efficacious shRNAs to the top of our shRNA offering. It's important to keep track of which TRCNs you've used in the past. The clones are all still there, and are visible on our website.

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Contact Us
For questions about the library, pricing and quotes or other concerns, please e-mail us at: MISSIONRNAi@sial.com.



MISSION is a trademark of Sigma-Aldrich. Label License.

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