Functional Genomics & RNAi siRNA

Advanced siRNA design and quality synthesis are crucial for a successful RNA interference experiment. Sigma's predesigned siRNA and siRNA libraries were designed using the Rosetta siRNA Design Algorithm to reduce off-target effects and provide guaranteed gene silencing. Coupled with our custom siRNA synthesis services and siRNA transfection reagents, we offer industry-leading technologies that enhance RNAi research.

For in vivo research, Sigma® provides MISSION® In Vivo Quality and iScale Oligos™ siRNA that deliver highly purified siRNA at the quantity necessary for successful in vivo experiments. Our expertise in oligo manufacturing allows us to offer a variety of modifications and scales suitable for any stage in your in vivo research.

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Custom siRNA synthesis

Products: New Products  MISSION esiRNA/esiFlex In Vivo Quality siRNA Predesigned siRNA Pre-arrayed siRNA Libraries Universal Negative Controls Positive Controls Custom siRNA Synthesis N-TER Transfection System    qRT-PCR for Knockdown Detection Online Product Catalog Academic Programs: Academic Programs Promotions: US Promotions

Learning Center: siRNA Protocols RNAi Process Diagram RNAi explained on "NOVA Science Now" RNAi Workflow FAQ Center  RNAi Literature References RNAi Glossary Press Releases Relevant Licenses for MISSION RNAi Products NCBI/HUGO/MGI Links Tool Box: Your Favorite Gene Search      Related Topics: Core Bioreagents  RNAi Books Labware