MISSION^® Positive Control siRNA

MISSION® Positive Control siRNA, designed using the Rosetta siRNA Design Algorithm, serve as an ideal complement to any siRNA silencing experiment. All MISSION® Positive Control siRNA have been validated to work*, so you can spend more time silencing your gene of interest and less time on optimizing internal controls.

Benefits of MISSION® Positive Control siRNA:

• Simplified optimization of siRNA transfection efficiency
• Increased target specificity, due to siRNA seed region optimization rules
• Validated gene silencing
• High quality siRNA produced at ISO 9000:2001 certified sites
• Freedom to operate for research use

Available MISSION® Positive Control siRNA
Human
Product	Gene
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
MAPK1	mitogen-activated protein kinase 1
KIF11	kinesin family member 11
Lamin A/C	lamin A/C
Cyclophilin B (PPIB)	peptidylprolyl isomerase B (cyclophilin B)
TP53	tumor protein p53 (Li-Fraumeni syndrome)

Rat
Product	Gene
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
MAPK1	mitogen-activated protein kinase 1
Lamin A/C	lamin A/C
Cyclophilin B (PPIB)	peptidylprolyl isomerase B
TP53	tumor protein p53

*Mission Positive Control siRNA reduce the level of gene target by >75%, 24 hours after transfection with 30nM siRNA (HeLa or 9L/lacZ cells).

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