Customer Education

Aldrich Materials Science Presents a Technical Webinar – Leveraging Physiology for Precise Drug Delivery



 Abstract

Spurred by recent advances in materials chemistry, molecular pharmaceutics and nanobiotechnology, stimuli-responsive “smart” systems offer opportunities for delivering drugs in dose-, spatial- and temporal-controlled fashions. In this talk, Professor Gu will present their ongoing efforts in using physiological signals, such as blood sugar level, enzyme activity and ATP gradient for on-demand drug release. The first half of the talk will cover the glucose-responsive synthetic systems for biomimetic delivery of insulin for diabetes treatment which will be followed by programmed delivery of anticancer therapeutics, the release of which can be activated in the tumor microenvironment or subcellular environment.

 

Speaker Bio
Dr. Zhen Gu
Dr. Zhen Gu received his B.S. degree in Chemistry and M.S. degree in Polymer Chemistry and Physics from Nanjing University. In 2010, he obtained his Ph.D. degree from the Department of Chemical and Biomolecular Engineering at the University of California, Los Angeles, under the guidance of Prof. Yi Tang. He was a postdoctoral associate working with Prof. Robert Langer and Prof. Daniel Anderson at Massachusetts Institute of Technology and Harvard Medical School from 2010 to 2012. He is currently an Assistant Professor in the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. He also holds joint positions in the Molecular Pharmaceutics Division in the UNC Eshelman School of Pharmacy and Endocrinology and Metabolism Division in the Department of Medicine. His group studies controlled drug delivery, bio-inspired materials and nanobiotechnology. He has published over 50 research papers and applied 20 patents. He is the recipient of the Pathway Award and Junior Faculty Award of the American Diabetes Association (ADA), Young Innovator Award in Cellular and Molecular Engineering of the Biomedical Engineering Society (BMES) and the Sigma Xi Young Faculty Research Award.

 

For more information email technicalworkshops@sial.com.