Enzyme Explorer

Proteasome


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Overview of Ubiquitin and the Proteasome Pathway

Product Guide:

Proteasome Pathway
Ubiquitination
Enzymes/Proteins
Prod No.: Product Name:
I 1154 Isopeptidase T *New
U 1633 Ubiquitin Activating Enzyme, Yeast *New
U 1758 Ubiquitin Activating Enzyme, Rabbit *New
U 2133 Ubiquitin C-Terminal Hydrolase, L3 *New
U 8382 Ubiquitin conjugating enzyme fractions (mammalian) *New
U 2633 Ubiquitin Carrier Protein H2 / E2-14K *New
U 2508 Ubiquitin Carrier Protein H2 *New
U 2383 Ubiquitin Carrier Protein H3 *New
U 8632 Ubiquitin-Carrier Protein H5a, GST-tagged human *New
U 8757 Ubiquitin-Carrier Protein H5b human *New
U 8882 Ubiquitin-Carrier Protein H5c human *New
U 9007 Ubiquitin-Carrier Protein H6 human *New
U 9132 Ubiquitin-Carrier Protein H7 human *New
U 9257 Ubiquitin-Carrier Protein H9 human *New
U 9382 Ubiquitin-Carrier Protein H10 human *New
U 5382 Ubiquitin, human, recombinant, N-terminal FLAG-tagged
U 5507 Ubiquitin, human, recombinant, N-terminal his-tagged
U 5632 Ubiquitin-Agarose
U 6253 Ubiquitin from bovine erythrocytes
U 8257 Ubiquitin Fraction FI from HeLa cells *New
U 8507 Ubiquitin K48R *New
Inhibitors
U 1507 Ubiquitin Aldehyde
U 1632 Ubiquitin, Methylated
Substrates
N 2030 NEDD8 precursor (Pro NEDD8) *New
N 8529 NEDD8 *New
S 0314 SUMO-1/Sentrin-1 human *New
S 0439 SUMO-1/Sentrin-1 human *New
U 5379 Anti-Ubiquitin from rabbit
U 2258 Ubiquitin-AMC *New
Proteasomes
Proteasome Fractions
Prod No.: Product Name:
F 3926 Fraction II [FII] (HELA) *New
F 4051 Fraction II [FII] (Rabbit reticulocyte) *New
P 3863 26S Proteasome Fraction from rabbit *New
P 3988 20S proteasome (mammalian) *New
P 4113 S-100 proteasome fraction from HeLa cells *New
Inhibitors
C 0358 CBZ-Leu-Leu-Phe-Al *New
C 2211 N-CBZ-Leu-Leu-Leucinal
C 6706 N-CBZ-Leu-Leu-Norvalinal
C 9857 CBZ-Leu-Leu-Leu-B(OH)2 *New
E 3652 Epoxomicin *New
E 3876 N-Ethylmaleimide
L 7035 clasto-Lactacystin b-lactone
L 6785 Lactacystin
G 9893 Gliotoxin
Substrates
C 0483 Z-Leu-Leu-Glu-7-amido-4-methylcoumarin *New
C 0608 Z-Leu-Leu-Leu-7-amido-4-methylcoumarin *New
C 0788 CBZ-Leu-Leu-Glu-ß-naphthylamide *New
Activator
P 5988 PA28 activator (mammalian) *New
Calpain
Enzymes
Prod No.: Product Name:
C 6108 Calpain I *New
P 4533 Calpain II
Inhibitors
A 6060 N-acetyl-Leu-Leu-Methioninal
A 6185 Calpain Inhibitor I
A 6191 Antipain Hydrochloride
C 4285 Acetyl-Calpastatin (184-210) Human
C 5913 4-Chloromercuribenzoic acid
C 8984 Z-Leu-Leu-Leu-fluoromethyl keytone *New
C 9181 Calpain Inhibitor Peptide
C 9234 Z-Leu-Leu-Tyr-fluoromethyl ketone *New
C 9859 Z-Leu-Leu-Tyr-CHN2 *New
E 0514 E-64c
E 8640 E-64d
L 2023 Leupeptin Trifluoroacetate salt
M 5439 N-Methoxysuccinyl-Val-HOMO-Phe-fluoromethyl ketone *New
M 6159 a2-Macroglobulin
M 6690 MDL 28170 (Calpain III inhibitor) *New
Substrates
S 1153 N-Succinyl-Leu-Tyr 7-amido-4-methylcoumarin
S 6510 Succinyl-Leu-Leu-Val-Tyr 7-amido-4-methylcoumarin
Antibodies
C 0230 Monoclonal Anti-m/5 Calpain, Small Subunit from mouse *New
C 0355 Monoclonal Anti-mu Calpain, Large Subunit, Clone 15C10, Mouse *New
C-269 Anti-Calpain (28 kDa subunit), monoclonal
C 5361 Anti-Mu-Calpain (Domain I) N-terminal
C 5486 Anti-Mu-Calpain (Domain I)
C 5861 Anti-Mu-Calpain (Domain I) N-terminal
C-266 Anti-mu-Calpain (Domain II), monoclonal
C-267 Anti-mu-Calpain (Domain II), monoclonal
C 0728 Anti-mu-Calpain Domain-III, large subunit
C-268 Anti-mu-Calpain (Domain III/IV), monoclonal
C 6111 Anti-M-Calpain (Domain III)
C 0478 Anti-LP-85 (lens-specific Calpain); Domain-IV, large subunit
C 0603 Anti-LP-82 (lens-specific Calpain)and LP-85; Domain-III, large subunit
C 6611 Anti-Calpain-94 (Domain I)
C 6486 Anti-Calpain-94 (Domain III)
C 6361 Anti-Calpain-94 (Domain II-Insert 1)
C 6236 Anti-Calpain-94 (Domain III-Insert 2)
C 5611 Anti-Mu-Calpain (Domain IV)
C 5736 Anti-Mu-Calpain (Domain IV) C-terminal
C 5986 Anti-Mu-Calpain (Domain IV) C-terminal
C-270 Anti-Calpastatin, monoclonal
Lysosomal Proteases
Cathepsin B
Enzymes
Prod No.: Product Name:
C 6286 Cathepsin B from bovine spleen 
C 8571 Cathepsin B from human liver 
C 0150 Cathepsin B from human placenta 
Inhibitors
A 6060 N-Acetyl-Leu-Leu-Met-al
A 6185 N-Acetyl-Leu-Leu-Norleu-al
A 6191 Antipain Hydrochloride
B 1932 Biotin-Phe-Ala-fluoromethyl ketone *New
C 0408 Cystatin
C 5732 CA-074 *New
C 5857 CA-074 Methyl Ester *New
C 7268 Chymostatin
C 8917 Cystatin
C 9109 Z-Phe-Phe-fluoromethyl keytone *New
E 3132 E-64 
L 2023 Leupeptin Trifluoroacetate Salt
M 5314 N-Methoxysuccinyl-Phe-HOMO-Phe-fluoromethyl ketone *New
M 6159 a2-Macroglobulin
P 0350 Procathepsin B Fragment 26-50, rat
P 0475 Procathepsin B Fragment 36-50, rat
Substrates
B 0885 Na-Benzoyl-L-arginine 4-methoxy-ß-naphthylamide HCl
C 2772 Z-Val-Lys-Lys-Arg-4-methoxy-b-naphthylamide trihydrochloride
C 3282 Z-Phe-Arg 4-methoxy-b-naphthylamide hydrochloride
C 5429 Z-Arg-Arg-7-amido-4-Z-RR-AMC-methylcoumarin hydrochloride
C 5520 Z-Arg-Arg 4-methoxy-b-naphthylamide acetate salt
C 8536 Z-Ala-Arg-Arg 4-methoxy-b-naphthylamide acetate salt
H 2508 Hippuryl-Arg
S 6510 N-Succinyl-Leu-Leu-Val-Tyr-7-Amido-4-Methylcoumarin
Cathepsin D
Enzymes
Prod No.: Product Name:
C 3138 Cathepsin D, Bovine
C 8696 Cathepsin D, Human
Inhibitors
A 6191 Antipain Hydrochloride
C 7268 Chymostatin
P 5318 Pepstatin A
Substrates
C 6358 N-Acetyl-Arg-Gly-Phe-Phe-Pro-7-amido-4-methylcoumarin *New
C 6983 N-Acetyl-Arg-Gly-Phe-Phe-Pro-7-amido-4-trifluoromethylcoumarin *New
M 0938 7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys (DNP)-D-Arg-amide *New
Antibodies
C 0715 Anti-Cathepsin D
Cathepsin H
Enzymes
Prod No.: Product Name:
C 8821 Cathepsin H, Human Liver *New
Inhibitors
C 0408 Cystatin
K 1632 Kininogen
L 2023 Leupeptin Trifluoroacetate Salt
Substrates
A 2027 L-Arginine-7-amido-4-methylcoumarin hydrochloride
Cathepsin L
Enzymes
Prod No.: Product Name:
C 6854 Cathepsin L, Human Liver *New
Inhibitors
A 6185 N-Acetyl-Leu-Leu-Norleu-al
C 9109 Z-Phe-Phe-fluoromethyl keytone *New
C 9234 Z-Leu-Leu-Tyr-fluoromethyl ketone *New
C 9859 Z-Leu-Leu-Tyr-CHN2 *New
M 5314 N-Methoxysuccinyl-Phe-HOMO-Phe-fluoromethyl ketone *New
Substrates
C 3282 Z-Phe-Arg 4-methoxy-b-naphthylamide hydrochloride
Antibodies
C 2970 Monoclonal Anti-Cathepsin L

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