Sigma-Aldrich
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Enzyme Explorer

Specificity Index I

Aminopeptidase
Angiotensin Converting Enzyme
APP-Secretase
b-Secretase
Bromelain
Calpains
Carboxypeptidases
Caspases
Cathepsin
Chymotrypsins


Clostripain
Collagenase
Complement C1, C1r & C1s
Complement Factors B & D
Dipeptidyl peptidase IV
Dispase
Elastases
Endoproteinase Arg-C, Glu-C, Lys-C
Factor VIIIa, Xa, XIa, XIIa
Ficin


gSecretase
Granzyme B
HIV Protease
Kallikreins
Leucine Aminopeptidases
Matrix metalloprotease
Metalloprotease inhibitors
Papain
Pepsin
Plasmin


Pro-caspase 3
Pronase E
Proteases
Proteasome inhibitor
Proteinase K
Renins
Thermolysin
Thrombin
Trypsin
Urokinase


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Aminopeptidase

Product Code Inhibitor
B8385 Bestatin
M6500 2-Mercaptoethylamine HCl

Aminopeptidase N

Product Code Inhibitor
P7240 Phebestin

Aminopeptidase P

Product Code Inhibitor
A1395 Apstatin

Angiotensin Converting Enzyme

Product Code Inhibitor
A0773 Angiotensin-converting enzyme inhibitor
B0507 Bradykinin potentiator B
B0632 Bradykinin potentiator C
C4042 Captopril
C8856 Captopril USP
F5017 Foroxymithine
F6800 Fenoldopam
S6633 N-Succinyl-L-proline
T7025 N-epsilon-Trifluoroacetyl-Lys-Pro

APP-Secretase

Product Code Inhibitor
A1847 [Asn670,Sta671,Val672]-Amyloid beta/A4 protein precursor 770 fragment (662-675)

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b-Secretase

Product Code Inhibitor
G8291 Glu-Val-Asn-[(2R,4S,5S)-5-Amino-4-Hydroxy-2,7-Dimethylocanoyl]-Ala-Glu-Phe
S4562 b-Secretase Inhibitor

Bromelain

Product Code Inhibitor
E3132 E-64
E3876 N-Ethylmaleimide
I2512 Iodoacetic Acid
T7254 N-a-p-Tosyl-L-lysine chloromethyl ketone Hydrochloride
T4376 N-a-p-Tosyl-L-phenylalanine chloromethyl ketone Hydrochloride

Calpain

Product Code Inhibitor
A6191 Antipain
C4285 Acetyl-Calpastatin (184-210) Human
C5913 p-Chloromercurbenzoic acid Free Acid
C8984 Z-Leu-Leu-Leu-Fluoromethyl ketone
C9234 Z-Leu-Leu-Tyr-Fluoromethyl ketone
C9859 Z-Leu-Leu-Tyr-CHN2
E0514 (2S,3S)-trans-Epoxysuccinyl-/L-leucylamido-3-methylbutane
E3876 N-Ethylmaleimide
E8640 (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester
L2023 Leupeptin
M5439 MeOSuc-Val-homo-Phe-fluoromethyl ketone
M6159 a2-Macroglobulin

Calpain I

Product Code Inhibitor
A6060 N-Acetyl-Leu-Leu-Met-al
A6185 N-Acetyl-Leu-Leu-Norleu-al
C9181 Calpain Inhibitor Peptide

Calpain II

Product Code Inhibitor
A6060 N-Acetyl-Leu-Leu-Met-al
A6185 N-Acetyl-Leu-Leu-Norleu-al
A6191 Antipain
C4285 Acetyl-Calpastatin (184-210) Human
C5913 p-Chloromercuribenzoic acid Free Acid
C9181 Calpain Inhibitor Peptide
E0514 (2S,3S)-trans-Epoxysuccinyl-/L-leucylamido-3-methylbutane
E3876 N-Ethylmaleimide
L2023 Leupeptin
M6159 a2-Macroglobulin

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Carboxypeptidase A

Product Code Inhibitor
C0279 Carboxypeptidase inhibitor
D6518 Diethylenetriaminepentaacetic acid Free Acid
ED2SS EDTA
E4378 EGTA
P9375 1,10-Phenanthroline Monohydrate

Carboxypeptidase B

Product Code Inhibitor
C0279 Carboxypeptidase inhibitor
D6518 Diethylenetriaminepentaacetic acid Free Acid
ED2SS EDTA
E4378 EGTA
P9375 1,10-Phenanthroline Monohydrate

Carboxypeptidase P

Product Code Inhibitor
C5913 p-Chloromercuribenzoic acid Free Acid
D5758 Deithyl pyrocarbonate
D0879 Diisopropyl fluorophosphate
I2512 Iodoacetic Acid

Carboxypeptidase Y

Product Code Inhibitor
A1153 Aprotinin
D0879 Diisopropyl fluorophosphate
P7626 Phenylmethylsulfonyl fluoride
 

Caspase

Product Code Inhibitor
B2057 Biotin-Val-Ala-Asp(OMe)-Fluoromethyl ketone
B2682 N-T-Boc-Asp(OMe)-fluoromethyl ketone
C8484 Z-Ala-Glu(OMe)-Val-Asp(OMe)-Fluoromethyl ketone
C8609 Z-Val-Lys(Biotin)-Asp(OMe)-Fluoromethyl ketone

Caspase 1

Product Code Inhibitor
A1466 N-Acetyl-Trp-Glu-His-Asp-al
A4211 N-Acetyl-Tyr-Val-Ala-Asp chloromethyl ketone
A4339 N-Acetyl-Tyr-Val-Lys(biotinyl)-Asp 2,6-dimethylbenzoyloxymethyl ketone
C9484 Z-Leu-Glu-(OMe)-Val-Asp(OMe)-Fluoromethyl ketone

Caspase 2

Product Code Inhibitor
A2222 N-Acetyl-Val-Asp-Val-Ala-Asp-CHO
C1605 N-Cbz-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK

Caspase 3

Product Code Inhibitor
A0835 N-AcetylL-Asp-Glu-Val-Asp-al
A1216 N-Acetyl-Ile-Glu-Thr-Asp-al
A1341 N-Acetyl-Glu-Ser-Met-Asp-al
B1807 Biotin-Asp-(OMe)-Glu-(OMe)Val(OMe)-Asp(OMe)-Fluoromethyl ketone
C0480 N-Cbz-Asp(OMe)-Gln-Met-Asp(OMe)-FMK
C0859 Caspase-4 Inhibitor (aldehyde)
V116 Z-VAD-FMK

Caspase 5

Product Code Inhibitor
A1466 N-Acetyl-Trp-Glu-His-Asp-al

Caspase 6

Product Code Inhibitor
A6339 N-Acetyl-Val-Glu-Ile-Asp-al
B1807 Biotin-Asp-(OMe)-Glu-(OMe)Val(OMe)-Asp(OMe)-Fluoromethyl ketone
C0480 N-Cbz-Asp(OMe)-Gln-Met-Asp(OMe)-FMK
C1730 N-CBZ-Val-Glu-(OMe)-Ile-Asp(OMe)-FMK

Caspase 7

Product Code Inhibitor
B1807 Biotin-Asp-(OMe)-Glu-(OMe)Val(OMe)-Asp(OMe)-Fluoromethyl ketone
C0605 N-Cbz-Asp(OMe)-GLu(OMe)-Val-Asp(OMe)-FMK

Product Code Inhibitor
A1216 N-Acetyl-Ile-Glu-Thr-Asp-al
B1807 Biotin-Asp-(OMe)-Glu-(OMe)Val(OMe)-Asp(OMe)-Fluoromethyl ketone
C1230 N-Cbz-Ile-Glu(OMe)-Thr-Asp(OMe)
C8734 Z-Leu-Glu-(OMe)-Thr-Asp-(OMe)-Fluoromethyl ketone

Caspase 9

Product Code Inhibitor
C1355 N-Cbz-Leu-Glu(OMe)-His-Asp(OMe)-FMK

Caspase 10

Product Code Inhibitor
B1807 Biotin-Asp-(OMe)-Glu-(OMe)Val(OMe)-Asp(OMe)-Fluoromethyl ketone

Caspase 13

Product Code Inhibitor
C8859 Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-Fluoromethyl ketone

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Cathepsin B

Product Code Inhibitor
A6060 N-Acetyl-Leu-Leu-Met-al
A6185 N-Acetyl-Leu-Leu-Norleu-al
A6191 Antipain
B1932 Biotin-Phe-Ala-Fluoromethyl ketone
C0408 Cystatin
C5732 CA-074
C5857 CA-074 Methyl ester
C7268 Chymostatin
C8917 Cystatin
C9109 Z-Phe-Phe-Fluoromethyl ketone
E3132 E-64
L2023 Leupeptin
M5314 MeOSuc-Phe-homo-Phe fluoromethyl ketone
M6159 a2-Macroglobulin
P0350 Procathepsin B, rat, fragment 26-50
P0475 Procathepsin B, rat, fragment 36-50

Cathepsin C

Product Code Inhibitor
I2512 Iodoacetic Acid

Cathepsin D

Product Code Inhibitor
A6191 Antipain
C7268 Chymostatin
P5318 Pepstatin A

Cathepsin G

Product Code Inhibitor
A9285 a1-Antchymotrypsin
C7268 Chymostatin
C9984 Z-Gly-Leu-Phe-Chloromethyl ketone
D0879 Diisopropyl fluorophosphate
D7910 3,4-Dichloroisocoumarin
E7888 N-Acetyl-eglin C

Cathepsin L

Product Code Inhibitor
A6185 N-Acetyl-Leu-Leu-Norleu-al
C9109 Z-Phe-Phe-Fluoromethyl ketone
C9234 Z-Leu-Leu-Tyr-Fluoromethyl ketone
C9859 Z-Leu-Leu-Tyr-CHN3
M5314 MeOSuc-Phe-homo-Phe fluoromethyl ketone

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