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Metabolomics

Glycolytic Pathway

Glycolytic-pathway-head

GLYCOLYSIS is the almost universal pathway that converts glucose into pyruvate together with NADH and a little ATP. In aerobic organisms the pyruvate passes into the mitochondria where it is completely oxidised by O2 into CO2 and H2O and its potential energy largely conserved as ATP. In the absence of sufficient oxygen the pyruvate is reduced by the NADH to a wide range of products, especially lactate in animals and ethanol in yeasts.


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The static chart below contains hyperlinks to the corresponding Sigma products. Just click on the metabolite to access product information.

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Hyperlinked Glycolytic Pathway Chart

Enzymes of Glycolysis

2.7.1.1 - Hexokinase
5.3.1.9 - Glucose-6-Phosphase Isomerase
2.7.1.11 - 6-Phosphofructokinase
4.1.2.13 - Fructose-bisphosphate aldolase
1.2.1.12 - Glyceraldehyde-3-phosphate dehydrogenase
2.7.2.3 - Phosphoglycerate kinase
4.2.1.11 - Phosphopyruvate hydratase (enolase)
2.7.1.40 - Pyruvate kinase
1.1.1.27 - Lactate dehydrogenase

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