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Non-nucleoside analog inhibitors

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60020 Caffeic acid purum, ≥95.0% (HPLC) A natural dietary phenolic compound found in plants that is an anti-oxidant. Inhibits the synthesis of leukotrienes that are involved in immunoregulation, inflammation and allergy. Inhibits Cu2+-induced LDL oxidation.
human ... ELA2(1991)
rat ... Alox5(25290)
C3878 Chlorogenic acid ≥95% (titration)   rat ... G6pc(25634)
E4143 (−)-Epigallocatechin gallate ≥95% Antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.
human ... CYP1A2(1544)
H1753 Hydralazine hydrochloride Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; antihypertensive; semicarbazide-sensitive amine oxidase inhibitor.
human ... MAOA(4128), MAOB(4129)
P9391 Procainamide hydrochloride Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Na+ channel blocker and Class IA anti-arrhythmic.
 
P9879 Procaine hydrochloride ≥97% Na+ channel blocker
 
R8279 RG108 ≥98% (HPLC), powder RG108 is a DNA methyltransferase (DMNT) inhibitor. It reactivates tumor suppressor gene expression (p16, SFRP1, secreted frizzled related protein-1, and TIMP-3) in tumor cells by DNA demethylation. RG108 also inhibits human tumor cell line (HCT116, NALM-6) proliferation and increased doubling time in culture.