Mass Spectrometry

The expanding field of proteomics involves many unique requirements, particularly in terms of specific reagent needs for Mass Spectrometry (MS). Sigma understands and meets these Mass Spectrometry needs, throughout your complete workflow.

  • For routine MALDI MS calibration, we offer the ProteoMass MALDI Calibration Kits, as well as individual highly purified ProteoMass MALDI matrices and a wide range of well-recognized, prequalified MALDI MS calibrants.
  • Our line of trypsin products is second to none. Trypsin, Proteomics Grade, offers superior sequence coverage while eliminating ambiguous autolytic MALDI peaks. The Trypsin Profile IGD kit enables fast, efficient, completed digestion from PAGE to MALDI.
  • The Protease Profiler provides four proven alternative proteases, in addition to trypsin, for protein digest prior to MS.
  • The ProteoMass Guanidination Kit enables dramatic improvement of MALDI MS sensitivity.
  • Through our new collaboration with SCIEX, Sigma-Aldrich is now offering a broad range of tagging chemistries for quantitative proteomics, including ICAT®, iTRAQ®, and mTRAQ®, as well as the CYP450 kits.

Please have a look at our Tools for Mass Spectrometry brochure to look at our portfolio of product offerings for mass spectrometry research in proteomics, as well as metabolomics.

With our targeted selection of kits, calibrants, matrices, and tagging reagents, Sigma is proud to meet your Mass Spectrometry reagent needs!