• Product Directory

    Custom Product

  • Services Offered

    Custom Capabilities
Decrease Font Size Increase Font Size Email this page to a friend Printer Friendly Page
Life Science > Molecular Biology > Whole Genome Amplification > WGA and WTA Services
Whole Genome Amplification

WGA and WTA Services

Rubicon Genomics LogoFor research requiring custom WGA/WTA project design and deliverables or the convenience of turn-key WGA/WTA solutions for large sample sets, Sigma® recommends Rubicon Genomics Amplification Services.

Rubicon has provided amplification services since 2003 and has unparalleled WGA/WTA expertise, having developed Sigma's GenomePlex and TransPlex kit technologies, as well as newer WGA technologies and methylation profiling (WMA) technologies for tissue, plasma, and serum samples.

A highly experienced team of Rubicon PhD scientists is available for scientific consultation and project management to provide customized solutions for a full range of applications, such as aCGH, qPCR, genotyping, sequencing, expression, and methylation.

Features available through Rubicon WGA and WTA Services:

  • Experienced PhD-level project managers
  • Client-specific project design
  • Complete spectrum of intact or degraded inputs (frozen/fixed tissue, single cells, plasma/serum, urine, blood cards, buccal swabs, etc.)
  • Efficient DNA/RNA extraction before WGA/WTA
  • DNA purification and quantification after WGA/WTA
  • Complete input/output QC and project report
  • Projects from one-hundred to ten-thousand samples
  • Amplified DNA validated for genetic, expression, and methylation studies using all PCR, array, and sequencing platforms

Rubicon WGA/WTA Service References

  1. New genetic associations detected in a host response study to hepatitis B vaccine
    Davila, S. et al. Genes and Immunity 11, 232-238 (2010)
    DNA extraction and WGA of 5000 serum samples
  2. Applications of combined DNA Microarray and Chromosome Sorting Technologies
    Gribble, S.M. et al. Chromosome Research 12:35-43 (2004)
    WGA of single flow-sorted chromosomes
  3. Variants in the gene encoding C3 are associated with asthma and related phenotypes among African Caribbean families
    Barnes, K.C. et al. Genes and Immunity 7, 27–35 (2006)
    WGA of ~1000 blood DNA samples
  4. WGA for The Wellcome Trust Sanger Institute
  5. WGA for The Cancer Genome Atlas (TCGA) Project

back to top