Plant Profiler California poppy (Eschscholzia californica)

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Pharmacology:

• Constituents: California poppy yielded alkaloids californidine, escholtzine, N-methyllaurotetanine, caryachine, O-methylcaryachine, and the pavine alkaloid, 6S,12S-neocaryachine-7-O-methyl ether N-metho salt in one study.¹
• Neurological: In an in vitro study, 70% ethanol extract of California poppy was able to bind to 5-HT(1A) and 5-HT(7) receptors.¹ The activity on the 5-HT(1A) receptor was at least partly due to the presence of the aporphine alkaloid 3.

Pharmacodynamics/Kinetics:

• Insufficient available evidence.

References

1. Gafner, S., Dietz, B. M., McPhail, K. L., Scott, I. M., Glinski, J. A., Russell, F. E., McCollom, M. M., Budzinski, J. W., Foster, B. C., Bergeron, C., Rhyu, M. R., and Bolton, J. L. Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. J Nat Prod  2006;69(3):432-435. 16562853

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