Attention:

Certain features of Sigma-Aldrich.com will be down for maintenance the evening of Friday August 18th starting at 8:00 pm CDT until Saturday August 19th at 12:01 pm CDT.   Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.


SILu™tions – Stable Isotope-labeled MS Internal Standards

What happens when you combine state-of-the-art technology with scientific prowess? Full-length protein standards with the highest purity and isotopic incorporation in the industry. Stable isotope-labeled (SIL) internal standards and high quality calibrations are the essential tools to precisely measure target protein quantitation in mass spectrometry proteomic assays. Our innovative SILutions portfolio meets the needs of different protein quantitation approaches. It’s innovation delivered to you – just right, right now.

For more tools to complete your workflow, visit sigma-aldrich.com/bioanalysis.
 

SILuProt (full-length proteins)
• Best MS proteomic internal standards
• Injected into sample before enzymatic
  digestion
• Cover major human biomarkers
• Unlabeled versions available for use as
  calibrators (SILu™Lite)

 
SILuMAb
• Full-length antibody protein standard
• Highly purified stable isotope-labeled
  universal IgG monoclonal antibody
• Critical tool for pharmacokinetic
  properties of biotherapeutics
• Unlabeled SigmaMAb available for MS
  calibration
 
SILuPrEST (50-150 aa)
• Intermediate in length between
  SILuProt and AQUA
• Substantial proteome coverage
• Injected into sample before or after
  enzymatic digestion
• Multiple tryptic peptides per SILuPrEST

 
AQUA (≤30 aa)
• Accurately quantitate low abundance
  proteins
• Measure site-specific phosphorylation
  states
• Injected into sample after enzymatic
  digestion
• Custom synthesis available