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Life Science > Proteomics > Sample Preparation > Protein Depletion > Seppro® Protein Depletion > IgY Mouse-Specific Columns

IgY Mouse-Specific Columns

Immunoaffinity partitioning of highly-abundant proteins (HAP) has proven to be one of the most effective approaches for overcoming the wide dynamic range of plasma protein concentration, as well as enabling the detection of low-abundant proteins (LAP). Avian polyclonal IgY (Immunoglobulin Yolk) antibodies have unique and advantageous features that allow highly-specific partitioning of protein mixtures. Sigma offers a novel Seppro® IgY-M7 column system, which takes you deeper into the mouse plasma/serum proteome.

Proteins Partitioned by IgY-M7 columns:

  • Mice Serum Albumin
  • IgG
  • Fibrinogen
  • Transferrin
  • IgM
  • Haptoglobin
  • alpha1-Antitrypsin

Columns are available in the following formats:

Product Name Column Use Mouse plasma/serum Product #
IgY-M7 Spin Column Kit
Includes 2 spin columns and reagents.
Good for 200 samples.
100 times 10µl SEP110 
IgY-M7 LC-10 Column Kit
Includes 1 HPLC column and reagents.
100 times 125µl SEP090 

 Dig deeper into the proteome with the Seppro Mouse SuperMix.  The SuperMix technology takes your depletion to the next level by further partitioning Moderately Abundant Proteins (MAP).

Product Name Column Use Mouse plasma/serum Product #
Mouse Supermix LC-5 Column Kit
Includes single SuperMix LC-5 column and reagents.
100 times – SEP100 

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