Induced Pluripotent Stem Cells from Proven Reprogramming Lentiviruses
SIGMA® Life Science and Stemgent have partnered to bring you proven reprogramming viruses for induced pluripotent stem cell (iPSC) generation. Available in DOX-inducible, non-inducible, and polycistronic formats for both human and mouse, Stemgent reprogramming viruses have been application tested and approved by leaders in the Stem Cell community. All six reprogramming factors are available as individual viruses and functional sets.
First produced in 2006 from mouse cells and in 2007 from human cells, induced pluripotent stem cells (iPSCs) are recognized by many as a breakthrough development in stem cell biology. IPSCs are created from differntiated cells, often fibroblasts, when they are reprogrammed through the introduction of specific genes. Cells then express these genes and reprogramming is achieved. Once reprogrammed, these new iPSCs resemble their pluripotent embryonic counterparts in many ways including embryoid body formation, teratoma formation, viable chimera formation, doubling, potency, differentiability, chromatin methylation patterns, and protein expression.
Experienced reprogramming scientists are ready to provide you technical expertise from experimental design through data interpretation, and each step in between. When you contact Sigma’s technical service group, you will be connected to the wealth of reprogramming expertise at Stemgent as well. Scientists at both companies will work with you to find the answers you need to make your reprogramming a success.
How to place your order
If you order through Stemgent, a Sigma representative will contact you to confirm your order.
How Lentiviruses will Arrive
Stemgent advances stem cell science by providing proprietary reagents and tools developed by some of the world's leading stem cell scientists. Stemgent's product offering has been specifically optimized for and screened against stem cells, and includes small molecules for pluripotency, self-renewal, and differentiation, viral-delivered transcription factors, matrices, cell lines, cytokines, antibodies, transfection reagents, and more. This unique product mix is designed to serve researchers who study stem cell biology and regenerative medicine, and those who use cells derived from stem cells as tools to advance their understanding of major diseases.
Sigma-Aldrich has been a leading Life Science and High Technology company since 1945. Through SIGMA Life Science we have developed tools enabling researchers to accelerate discovery across the entire drug development research workflow including RNAi and sample prep platforms. For stem cell research, Sigma offers a comprehensive and unprecedented number of products to support scientists in the discovery efforts to better understand the cellular processes controlling development, aging, disease and tissue regeneration. Our product offering includes media, antibodies, 3D matrices, growth factors, small molecules, RNAi, and Zinc Finger Nuclease Technology.