Customer Favorite Genes

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EaJanssen – Norway
My favorite gene is DIRAS3/ARHI/Noey2. It’s a small protein with many different functions, and (and what is) still elusive is its function is in carcinogenesis.

Sanja P. – Canada
My favorite gene is retinoblastoma because it is the guardian of the genome.

P2RX7 – Mexico
My favorite gene is P2RX7; purinergic receptor P2X, ligand gated ion channel 7. P2RX7 receptors play a specific role in nociceptive signaling in chronic pain states, almost is increasingly recognised as an important cell curface regulator of several key inflammatory molecules.

L. Kippner – USA
My favorite gene is SPIC. It was the gene that really opened my eyes to the wonderful complexity of the genomic processes - it was the basis for my master's thesis. You never forget your first gene.

G. L. – USA
My favorite gene is Extracellular Calcium-Sensing Receptor (CaR). It is very adaptable, and keeps many of it functions unknown!

Kefas B. – USA
My favorite gene is Pyruvate Kinase M2. This gene is exclusively expressed in tumors, thus a good therapeutic target that will have minimal side effect.

Mark H. – New Zealand
My favorite gene is nsd1. NSD1 is a nuclear associated histone methyl transferase. Defects of this gene are associated with SOTOS syndrome, Weaver syndrome and Beckwith-Wiedemann syndrome (overgrowth syndromes). A fusion protein with NUP98 is commonly seen in childhood acute myeloid leukemia.

Anonymous – Canada
My favorite gene is SPP (Signal peptide peptidase). That is the gene I have working on for the last few years.

B. Takabe – Canada
My favorite gene is Pax6. It’s the “master” control gene for eye development across species.

David L. – USA
My favorite gene is BRCA2. It will detect problems and give time to treat them.

Anonymous – USA
My favorite gene is Smad4. I’m currently working on it.

A. V. – USA
My favorite gene is HDAC11. Is the last HDAC discovered, and still nobody knows its importance in any cellular process...but i have a hint : )

Ananth, M. – USA
My favorite gene is Sodium bile acid cotransporting polypeptide (Slc10A1). It transports bile acids into liver and thus carries out an important function in liver.

Anonymous – Canada
My favorite gene is Proghrelin. It's the gene encoding for the orexigenic hormone Ghrelin, an important regulator of energy homeostasis.

Kristen B. – USA
My favorite gene is Thioredoxin Reductase. It's a main component in the response to oxidative stress and it is inducible by H₂O₂.

Ioannis – Greece
My favorite gene is GLUD2 (glutamate dehydrogenase 2) because I worked with this gene in my PhD years.

Paul E. – USA
My favorite gene is IRAS/Nischarin because I helped discover it.

QQ – USA
My favorite gene is SNAP-25. It plays important roles in neurotransmit.

Anonymous – USA
My favorite gene is huntingtin. Big protein - no known function.

Anonymous – USA
My favorite gene is IKAP. Mutations in this gene cause a devastating human disease, Familial Dysautonomia.

Fred – USA
My favorite gene is NOD2. The various clinical manifestations of the gene and its role in the infalamtion process.

AJ – USA
My favorite gene is RAP80 because it's involved in the DNA Repair and is a very hot gene.

Anonymous – USA
My favorite gene is slr1128 because it's highly reserved.

Anonymous – Luxembourg
My favorite gene is StuA because it controls lot of activities in the cell.

Anonymous – USA
My favorite gene is JARID1C because I have worked on it.

Navdar S. – USA
My favorite gene is Smoothened (SMO) because it has 7 transmembrane domains but it is not coupled to G proteins.

Thomas W. Chung – USA
My favorite gene is Sonic hedgehog homolog (SHH). It's a cleverly named developmental signaling gene.

Muktar Mahajan – USA
My favorite gene is p53. It is a guardian of the human genome.

Herb P. – USA
My favorite gene is Lmna. Who knew one little gene could cause so much trouble?

Anonymous – USA
My favorite gene is MKS1/BBS13. I worked on the BBS family for many years, and we got all the way up to number 13. I finally got a first author paper on MKS1, aka BBS13.

Anonymous – USA
My favorite gene is vldlr. Mysterious functions.

Patrudu – USA
My favorite gene is p53. Its most exciting and associated with many diseases.

Anonymous – USA
My favorite gene is Glyceraldehyde-3 phosphate dehydrogenase. (GAPDH) This gene is a gene encodes an enzyme in central metabolism, but the protein has also been found to help transport mRNA from the nucleus of cells, perhaps giving a link between gene expression and energy levels.

Steve M. – USA
My favorite gene is glossy15. (G115) (maize). It's the most beautiful gene in the world—helping plants transition from juvenile to adult!

Gustavo K. – USA
My favorite gene is APOBEC3G potent restriction of retroviruses.

JD – USA
My favorite gene is interleukin-1. (IL-1) Why not?

Jess Thoene, M.D.
My favorite gene is CTNS. Defects cause cystinosis, the disease I have spent my life investigating.

Anirban Mitra – USA
My favorite gene is KDR. We have shown that this gene is predictive of nodal metastasis in bladder cancer (as part of a signature).

Anonymous – USA
My favorite gene is YAP (Yes-associated Protein). New oncogene; co-transcription factor involved in the Hippo pathway, which is important in regulating organ size.

M.C. Aakre – USA
My favorite gene is MECP2. Its leading sex linked cause of mental retardation in females. (Rett Syndrome)

Anonymous – USA
My favorite gene is SOD2 (MnSOD). It is still poorly explored.

Mike F. – USA
My favorite gene is AtXrn2. It's protein chews up RNA. And only in eukaryotes.

Anonymous – USA
My favorite gene is MYC. It is involved in almost every major biological pathway

VS – USA
My favorite gene is 3-OST-2. It makes a great cancer specific marker.

Keith H. – USA
My favorite gene is WNT. Key role in development and oncogenesis with beautiful pathway maps to boot.

DD – USA
My favorite gene is Renin (rat) (REN1). Roles in blood pressure and angiogenesis.

Carrie Paquette-Straub – USA
My favorite gene is KiSS1. I worked with one of the people who discovered the gene, and also worked on research with the gene for 5 years. I like the story behind how they choose the name for the gene, incorporating their proximity to the Hershey's Chocolate Factory.

Takeo M. – USA
My favorite gene is Dopamine D3 receptor. D3R plays key roles in the goal-directed behavior and dopaminergic disorders. Regardless of its functional significance, D3R tends to be neglected as compared to D1R and D2R which are more extensively validated. D3R can be coupled to various intracellular signaling and co-expressed with other DAR subtypes, thus D3R can orchestrate the DA effect.

Nicole Schechter – USA
My favorite gene is TAS2R38 receptor gene. The discovery of the taste receptor gene allows us to begin to understand genetic differences in taste sensitivity and perhaps food preference.

Huayi Huang – USA
My favorite gene is NET-6. It is a newly indentified tumor suppressor gene.

Theresa C. – USA
My favorite gene is Collagen II. (COL2A1) Published my first paper based on results with this gene.

Anonymous – USA
My favorite gene is BCRP/ABCG2. It is the gene that I worked on in graduate school. BCRP is unique because it is an ABC transporter composed of only one transmembrane region and one ATP-binding domain. Also, its function as an efflux transporter requires heterodimerization or homodimerization which is why it is referred to as a half-transporter.

Donna B. – USA
My favorite gene is Mapk14. It's one of several genes whose expression was found to be lowered in the brains of irradiated rats, yet up-regulated in irradiated rats fed a berry-supplemented diet, indicating that the berry diets afforded protection against the effects of irradiation through enhancement of neuronal communication and signaling.

Pdk – USA
My favorite gene is globin. An extraordinary amount of biological effort is dedicated to transcribing and translating globins.

Nancy R. – USA
My favorite gene is FIC1 because it translocates phospholipids.

ADC – USA
My favorite gene is PTEN—an amazing tumor suppressor.

Anonymous – USA
My favorite gene is MLCK2. It's role in Acute Lung Injury (what the lab studies).

Michelle A. – USA
My favorite gene is R2D2. What a wonderful name! It has a very important function in the endogenous RNAi pathway.

Zoe – USA
My favorite gene is VDR. I’m studying it.

Emmidoo – USA
My favorite gene is human vomeronasal organ receptor genes. (LOC171266) I cloned them.

J.R. – USA
My favorite gene is Jak3. You don't know Jack until you know Jak!

Anonymous – USA
My favorite gene is Amyloid precursor protein (APP). Understanding APP metabolism will help prevent/treat Alzheimer's Disease.

Anonymous – USA
My favorite gene is Cytochrome B. It is the first gene I sequenced as an undergrad.

Anonymous – USA
My favorite gene is SPARC. It is central to extracellular matrix deposition control.

Gary B. – USA
My favorite gene is IL1B. It is one of the main control points of the inflammatory response.

Christine H. – USA
My favorite gene is Hedgehog. Important gene in signaling during development.

MAC – USA
My favorite gene is SDF-1 (CXCL12). Discovering SO MANY new and interesting properties of this gene...never seems to end!

Auh2o – USA
My favorite gene is c-Myc. The c-Myc oncogenic transcription factor (Myc) is widely over-expressed in cancers. Constitutive Myc expression alters the Myc target gene network and contributes to a dose-dependent tumorigenesis. MYC dose is also important for sustaining tumorigenesis such that removal of MYC expression can cause remarkable tumor regression in transgenic mice.

Sharmistha – USA
My favorite gene is Constitutive androstane receptor alpha (human) (CAR). I am targetting this gene for cancer therapy.

DJ – USA
My favorite gene is ELOVL4. I spent my graduate career trying learning what it does and how it is involved in macular degeneration.

Anonymous – USA
My favorite gene is myc. It is used to create ips lines.

Heidi G. – USA
My favorite gene is UCP1. I studied it for several years.

Tatyana – Russia
My favorite gene is Alu. They are so numerous and still mysterious. We still don't know why they were so successful in our genome and what they do there, although no doubt they in many ways are very useful for us.

Anonymous – USA
My favorite gene is soluble guanylate cyclase aplha 1 (GUCA1A). Isn't it obvious?

A. – India
My favorite gene is HMGB1. It’s a cytokine, cell signaling moloecule,pluripotency gene, differentiation marker!

John L. – USA
My favorite gene is CD133. The potential to measure, track and modulate sensitivity of cancer initiating cells.

Dan F. – USA
My favorite gene is Clusterin (CLU). Multifunctional gene product, contributing to diverse cellular processes.

Varadaraj – USA
My favorite gene is aquaporin (AQP). It is present plant, animal and microbes. In human it is linked to several diseases.

Eric H. – USA
My favorite gene is Prolactin (PRL). It is a very under appreciated hormone. There is much more to it than "Got Milk?"

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