Monofunctional PEGs

Sigma-Aldrich offers monofunctional poly(ethylene glycol) (PEG), otherwise known as poly(oxyethylene) or poly(ethylene oxide) (PEO), derivatives in a range of molecular weights, containing a single functional group of various functionalities, such as amines, maleimides, azides, NHS esters, thiols and many more. The diverse offering of PEGs by Sigma-Aldrich allows for easy incorporation of PEG into proteins, peptides, surfaces, and other materials.

To view a list of products filtered by functionality, simply click on the "+" sign on the functionality column and make your selection. Alternatively, you can browse through all available functionalities in the table immediately below.

Product #

Structure

Product Name

Mol. Wt.

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750069 2-Bromoisobutyrate
Poly(ethylene glycol) methyl ether 2-bromoisobutyrate average Mn 2,000 average Mn 2,000
767581 2-Bromoisobutyrate
Poly(ethylene glycol) methyl ether 2-bromoisobutyrate average Mn 600 PEG average Mn 350 (n~8)
average Mn 600
736333 2-Bromoisobutyrate
Poly(ethylene glycol) methyl ether 2-bromoisobutyrate average Mn 5,000 average Mn 5,000
739456 2-Bromoisobutyrate
Poly(ethylene glycol) methyl ether 2-bromoisobutyrate average Mn 1,200 average Mn 1,200
17359 4-(Hydroxymethyl)benzoyl
O-[4-(Hydroxymethyl)benzoyl]-O′-methyl-polyethylene glycol 5000 ≥80% (NMR) average Mw 5,000
699802 Acetylene
Poly(ethylene glycol)methyl ether acetylene average Mn 2,000 average Mn 2,000
JKA13006 Acrylate
mPEG12-Acrylate  
JKA13005 Acrylate
mPEG5-Acrylate  
JKA13007 Acrylate
mPEG6-Acrylate  
JKA13008 Acrylate
mPEG7-Acrylate  
730270 Acrylate
Poly(ethylene glycol) methyl ether acrylate average Mn 2,000, contains MEHQ as inhibitor average Mn 2,000
730289 Acrylate
Poly(ethylene glycol) methyl ether acrylate average Mn 5,000, contains MEHQ as inhibitor average Mn 5,000
54369 Aldehyde
O-[2-(6-Oxocaproylamino)ethyl]-O′-methylpolyethylene glycol 2′000  
41964 Aldehyde
O-[2-(6-Oxocaproylamino)ethyl]-O′-methylpolyethylene glycol 5′000  
JKA3177 Alkyne
mPEG5K-Alkyne average Mn 5,000 average Mn 5,000
06679 Amine
Methoxypolyethylene glycol amine 5,000, extent of labeling: ≥0.17 mmol/g NH2 loading  
06676 Amine
Methoxypolyethylene glycol amine 2,000, extent of labeling: ≥0.4 mmol/g NH2 loading  
07965 Amine
Methoxypolyethylene glycol amine 10,000  
07966 Amine
Methoxypolyethylene glycol amine 20,000  
07964 Amine
Methoxypolyethylene glycol amine 750  
JKA13003 Amine
mPEG12-NH2  
JKA13020 Amine
mPEG5-NH2  
JKA13001 Amine
mPEG6-NH2  
JKA13021 Amine
mPEG7-NH2  
767565 Amine
Poly(ethylene glycol) methyl ether amine average Mn 500 PEG average Mn 450 (n~10)
average Mn 500
689807 Azide
Methoxypolyethylene glycol azide PEG average Mn 2,000 PEG average Mn 2,000
689475 Azide
Methoxypolyethylene glycol azide PEG average Mn 5,000
726168 Azide
Methoxypolyethylene glycol azide PEG average Mn 10,000 PEG average Mn 10,000
726176 Azide
Methoxypolyethylene glycol azide PEG average Mn 20,000 PEG average Mn 20,000
JKA13019 Azide
mPEG12-Azide  
JKA13016 Azide
mPEG5-Azide  
JKA13017 Azide
mPEG6-Azide  
JKA13018 Azide
mPEG7-Azide  
712590 Azide
O-(2-Azidoethyl)-O′-methyl-triethylene glycol ≥90% (NMR) average Mn 200
712604 Azide
O-(2-Azidoethyl)-O′-methyl-undecaethylene glycol ≥90% (NMR)  
726249 Azide
O-(2-Azidoethyl)nonadecaethylene glycol ≥95% (oligomer purity)  
767557 Azide
Poly(ethylene glycol) methyl ether azide average Mn 400 PEG average Mn 350 (n~8)
average Mn 400
733407 Azide
Poly(ethylene glycol) methyl ether azide PEG average Mn 1,000 PEG average Mn 1,000
407003 Carboxylic Acid
2-[2-(2-Methoxyethoxy)ethoxy]acetic acid technical grade  
70718 Carboxylic Acid
Methoxypolyethylene glycol 5,000 acetic acid ≥80%  
88908 Carboxylic Acid
Methoxypolyethylene glycol 5,000 propionic acid ≥80%  
21954 Carboxylic Acid
O-[2-(3-Succinylamino)ethyl]-O′-methyl-polyethylene glycol PEG average Mn 20,000 PEG average Mn 20,000
689556 Carboxylic Acid
O-(2-Carboxyethyl)-O′-methyl-undecaethylene glycol ≥95% (oligomer purity)  
17928 Carboxylic Acid
O-Methyl-O′-succinylpolyethylene glycol 2′000 Mr ~2100
17929 Carboxylic Acid
O-Methyl-O′-succinylpolyethylene glycol 5′000 Mr ~5100
JKA3060 Hydrazide
mPEG5K-Hydrazide average Mn 5,000 average Mn 5,000
JKP12002 Hydroxy
mPEG5-OH  
418366 Hydroxy
Poly(ethylene glycol) butyl ether average Mn ~206 average Mn ~206
202487 Hydroxy
Poly(ethylene glycol) methyl ether average Mn 550 average Mn 550
202495 Hydroxy
Poly(ethylene glycol) methyl ether average Mn 750 average Mn 750
202509 Hydroxy
Poly(ethylene glycol) methyl ether average Mn ~2,000, flakes average Mn ~2,000
81323 Hydroxy
Poly(ethylene glycol) methyl ether average Mn 5,000 average Mn 5,000
81321 Hydroxy
Poly(ethylene glycol) methyl ether average Mw 2,000 average Mw 2,000
71578 Hydroxy
Poly(ethylene glycol) methyl ether BioUltra, 500 mol wt 470-530
732621 Hydroxy
Poly(ethylene glycol) methyl ether average Mn 10,000 average Mn 10,000
732613 Hydroxy
Poly(ethylene glycol) methyl ether average Mn 20,000 average Mn 20,000
705276 Hydroxy
Tetraethyleneglycol monomethyl ether technical grade average Mn 200
568554 Hydroxy
Tri(ethylene glycol) monoethyl ether technical grade  
317292 Hydroxy
Triethylene glycol monomethyl ether 95%  
JKA3189 Isocyanate
mPEG5K-Isocyanate average Mn 5,000 average Mn 5,000
712558 Maleimide
Methoxypolyethylene glycol maleimide 750 PEG average Mn 750
63187 Maleimide
Methoxypolyethylene glycol maleimide ≥90% (NMR), 5,000 PEG average Mn 5,000
712469 Maleimide
Methoxypolyethylene glycol maleimide PEG average Mn 10.000 PEG average Mn 10.000
JKA3115 Maleimide
mPEG20K-MAL average Mn 20,000 average Mn 20,000
JKA3124 Maleimide
mPEG2K-MAL average Mn 2,000 average Mn 2,000
JKA3123 Maleimide
mPEG40K-MAL average Mn 40,000 average Mn 40,000
731765 Maleimide
Poly(ethylene glycol) methyl ether maleimide average Mn 2,000 average Mn 2,000
17894 Mesylate
Polyethylene glycol monomethyl ether mesylate 2,000  
17893 Mesylate
Polyethylene glycol monomethyl ether mesylate 5,000  
447935 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate average Mn 300, contains 100 ppm MEHQ as inhibitor, 300 ppm BHT as inhibitor average Mn 300
447943 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate average Mn 500, contains 100 ppm MEHQ as inhibitor, 200 ppm BHT as inhibitor average Mn 500
447951 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate average Mn 950, contains 100 ppm MEHQ as inhibitor, 300 ppm BHT as inhibitor average Mn 950
730319 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate average Mn 1500, contains ≤300 ppm monomethyl ether hydroquinone as stabilizer average Mn 1500
730327 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate average Mn 4,000, contains ≤300 ppm monomethyl ether hydroquinone as inhibitor average Mn 4,000
457876 Methacrylate
Poly(ethylene glycol) methyl ether methacrylate solution average Mn 2,000, 50 wt. % in H2O average Mn 2,000
729841 Methacrylate
Triethylene glycol methyl ether methacrylate contains MEHQ as inhibitor, 93% average Mn 200
85973 NHS Ester
Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester ≥80% PEG average Mn 5,000
712531 NHS Ester
O-[(N-Succinimidyl)succinyl-aminoethyl]-O′-methylpolyethylene glycol 750  
41214 NHS Ester
O-[(N-Succinimidyl)succinyl-aminoethyl]-O′-methylpolyethylene glycol 2′000  
JKA3106 Phospate
mPEG5K-Phosphate average Mn 5000 average Mn 5000
JKA3033 Propionaldehyde
mPEG10K-Propionaldehyde average Mn 10,000 average Mn 10,000
JKA3039 Propionaldehyde
mPEG5K-Propionaldehyde average Mn 5,000 average Mn 5,000
JKA13002 Propionic Acid
mPEG12-Propionic acid  
JKA13011 Propionic Acid
mPEG6-Propionic acid  
JKA13009 Propionic Acid
mPEG7-Propionic acid  
900498 Pyrene
Methoxypolyethylene glycol pyrene average Mn 2,000 New average Mn 2,000
764930 RAFT
Poly(ethylene glycol) 4-cyano-4-(phenylcarbonothioylthio)pentanoate average Mn 10,000 average Mn 10,000
764914 RAFT
Poly(ethylene glycol) 4-cyano-4-(phenylcarbonothioylthio)pentanoate average Mn 2,000 average Mn 2,000
752495 RAFT
Poly(ethylene glycol) methyl ether (2-methyl-2-propionic acid dodecyl trithiocarbonate) average Mn 10,000 average Mn 10,000
751626 RAFT
Poly(ethylene glycol) methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) average Mn 5,400 average Mn 5,400
751634 RAFT
Poly(ethylene glycol) methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) average Mn 2,400 average Mn 2,400
752487 RAFT
Poly(ethylene glycol) methyl ether (4-cyano-4-pentanoate dodecyl trithiocarbonate) average Mn 1,400 average Mn 1,400
736325 RAFT
Poly(ethylene glycol) methyl ether 2-(dodecylthiocarbonothioylthio)-2-methylpropionate average Mn 5,000 average Mn 5,000
740705 RAFT
Poly(ethylene glycol) methyl ether 2-(dodecylthiocarbonothioylthio)-2-methylpropionate average Mn 1,100 average Mn 1,100
JKA3100 Silane
mPEG20K-Silane average Mn 20000 average Mn 20000
JKA3037 Silane
mPEG5K-Silane average Mn 5,000 average Mn 5,000
JKA3016 Succinimidyl Carboxymethyl Ester
mPEG10K-Succinimidyl Carboxymethyl Ester average Mn 10,000 average Mn 10,000
JKA3003 Succinimidyl Carboxymethyl Ester
mPEG20K-Succinimidyl Carboxymethyl Ester average Mn 20,000 average Mn 20,000
JKA3004 Succinimidyl Carboxymethyl Ester
mPEG30K-Succinimidyl Carboxymethyl Ester average Mn 30,000 average Mn 30,000
JKA3041 Succinimidyl Carboxymethyl Ester
mPEG40K-Succinimidyl Carboxymethyl Ester average Mn 40,000 average Mn 40,000
JKA3076 Thioctic acid
mPEG2K-Thioctic acid average Mn 2000 average Mn 2000
JKA13015 Thiol
mPEG12-SH  
JKA13012 Thiol
mPEG5-SH  
JKA13013 Thiol
mPEG6-SH  
JKA13014 Thiol
mPEG7-SH  
11124 Thiol
O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol 5,000  
63753 Thiol
O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethylene glycol 20′000  
672572 Thiol
O-(2-Mercaptoethyl)-O′-methyl-hexa(ethylene glycol) ≥95% (oligomer purity) PEG average Mn 350
743127 Thiol
O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 2,000 average Mw 2,000
743011 Thiol
O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 10,000 average Mw 10,000
729159 Thiol
Poly(ethylene glycol) methyl ether thiol average Mn 6,000 average Mn 6,000
729140 Thiol
Poly(ethylene glycol) methyl ether thiol average Mn 2,000 average Mn 2,000
729108 Thiol
Poly(ethylene glycol) methyl ether thiol average Mn 800 average Mn 800
729116 Tosylate
Poly(ethylene glycol) methyl ether tosylate average Mn 900 average Mn 900
729124 Tosylate
Poly(ethylene glycol) methyl ether tosylate average Mn 2,000 average Mn 2,000
729132 Tosylate
Poly(ethylene glycol) methyl ether tosylate average Mn 5,000 average Mn 5,000