| Solubility Properties of PAMAM Dendrimers |
I - Insoluble S - Soluble G - Gel-like B - Borderline |
Solubilities of Generation 5 PAMAM dendrimers with different surface groups in common solvents. Solubility shown after 15 minutes of addition of solvent and after 24 hours of tumbling. |
Solvent (dielectric constant) |
Surface Group |
| Amine |
Ethanol Amine |
50/50 Cs/Amine |
Cs |
Vinyl |
Carboxylic Acid |
| 15min |
24hr |
15min |
24hr |
15min |
24hr |
15min |
24hr |
15min |
24hr |
15min |
24hr |
|
Pentane
(1.841) |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
| Methyl Cyclohexane (2.020) |
I |
I |
I |
I |
I |
I |
S |
S |
I |
I |
I |
I |
|
Cyclohexane
(2.02431) |
I |
I |
I |
I |
I |
I |
S |
S |
I |
I |
I |
I |
|
Toluene
(2.3807) |
I |
I |
I |
I |
I |
I |
S |
S |
I |
S |
I |
I |
|
Chloroform
(4.81) |
I |
I |
I |
I |
S |
S |
S |
S |
S |
S |
I |
I |
|
Tetrahydrofuran
(7.58) |
I |
I |
I |
I |
I |
S |
S |
S |
S |
S |
I |
I |
|
Pyridine
(12.91) |
B |
B |
I |
G |
S |
S |
S |
S |
B |
S |
I |
I |
|
2-Pentanol
(13.71) |
B |
S |
S |
S |
S |
B |
B |
S |
I |
S |
I |
I |
|
Ethylene Glycol
(17.10) |
S |
S |
I |
S |
B |
S |
I |
I |
I |
S |
I |
S |
|
1-Butanol
(17.8) |
S |
S |
S |
S |
S |
S |
S |
S |
I |
S |
I |
I |
|
Ethyl Alcohol
(24.6) |
S |
S |
B |
S |
S |
S |
S |
S |
S |
S |
I |
S |
|
Acetonitrile
(35.94) |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
I |
|
Dimethylformamide
(36.71) |
B |
S |
S |
S |
S |
S |
S |
S |
S |
S |
I |
I |
|
Dimethylacetamide
(37.8) |
B |
S |
S |
S |
S |
S |
S |
S |
B |
S |
I |
I |
|
Dimethyl Sulfoxide
(47.2) |
B |
S |
I |
S |
S |
S |
I |
S |
I |
S |
I |
S |