Join Researchers at the Cutting Edge of Gene Editing

When Core Facilities partner with Sigma-Aldrich, we empower researchers with greater access to genome editing technologies and supporting resources. Therefore, breakthrough discoveries can be made more quickly, confidently, and accurately. Sigma-Aldrich’s scientific expertise and knowledge spans the entire experimental workflow from assay design and bioinformatics, manufacturing, validation, and application testing in gene editing and RNAi.

  • Partner with industry leader in gene editing
  • Scientific seminars and webinars
  • Priority technical support: Experimental design and troubleshooting
  • Pre-designed CRISPRs for the human, mouse and rat genomes
  • Custom CRISPR designs and project consultation
  • Early access to new technology

Click here to read the Top 10 Innovation Award News Release



 Current Partners

North America

Cedars-Sinai Mouse Genetics Core

Cleveland Clinic Molecular Screening Core

Columbia University Medical Center - Columbia Genome Center High-Throughput Screening Core

Duke Functional Genomics Shared Resource

Emory Transgenic Mouse and Gene Targeting Core

Genetic Resources Core Facility, Johns Hopkins University School of Medicine

Goodman Cancer Centre Transgenic Core Facility, McGill

Icahn School of Medicine at Mount Sinai - Human Embryonic Stem Cell Core

Inflammagen-Integrative Genomic Medicine

Medical College of Wisconsin Transgenic Core

Moffit Cancer Center-Molecular Genomics Core Facility

Mouse Genetic Engineering Facility, UT Austin

New Jersey Medical School Rutgers Genome Editing Core Facility

Northwestern University Transgenic and Targeted Mutagenesis Laboratory (TTML)

NYU Langone- RNA format - Rodent Genetic Engineering Core

NYU School of Medicine - RNAi Screening and Automation Core

SPARC Biocentre - Hospital for Sick Children, Toronto

Texas A&M Institute for Genomic Medicine (TIGM)

Transgenic Mouse Facility University of Illinois at Urbana Champaign

University of Calgary Transgenic Services

University of California, Los Angeles Vector Core

University of Colorado - Aurora Medical Campus

University of Florida Interdisciplinary Center for Biotechnology Research

University of Maryland-Center for Innovative Biomedical Resources

University of Michigan Medical School’s Vector Core

University of Michigan Transgenic Animal Model Core


North America (cont.)

University of Montreal Hospital Research Centre (CRCHUM) Transgenics Laboratory

University of Saskatchewan

University of Texas Health Science Center at Houston Transgenic Core

University of Texas Southwestern Medical Center Transgenic Core

Vanderbilt Transgenic Mouse/Embryonic Stem Cell Shared Resource (TMESCSR)


ASCR, The Czech Centre for Phenogenomics

Centre for Genomic Regulation- Biomolecular Screening & Protein Technologies Unit

Centro Nacional de Biotecnologia (CNB) Transgenics Unit

Copenhagen Center for Glycomics


ETH Zurich

Danish Cancer Research Center- Signaling Group

Francis Crick Institute- High Throughput Screening Facility

Helsinki University - Biomedicum Functional Genomics Unit

Ospedale San Raffaele (OSR)

Leiden University Medical Centre (LUMC)

Sahlgrenska Academy- Anders Lindahls Research Group

Transgenic Core Facility (CBATEG) at the Universitat Autònoma de Barcelona (UAB)

Translational Research Resource Center , MRC Laboratory for Molecular Cell Biology, University College London

Turku Center for Disease Modeling

University of Copenhagen - Core Facility for Transgenic Mice

University of Helsinki- Laboratory Animal Centre GM Unit

Universite de Liege - GIGA Viral Vector Platform

University Medical Center Goettingen (UMG) - Institute of Pharmacology

 Current CRISPR Products

  • Single vector CRISPR system
        – U6-gRNA/Cas9-GFP
        – U6-gRNA/Cas9-RFP
  • Dual vector CRISPR system
        – Cas9 and gRNA
  • CRISPR Paired Nickases
  • RNA format for microinjection
  • Lentiviral CRISPRs  
        – single clones
        – lentiviral pools for screening
  • Positive controls
  • Negative controls


 Custom Opportunities

  • Lentiviral pools: human library, human kinase library and custom libraries