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Manufacturing Sites
State-of-the-Art Production
 The SAFC Hamburg plant is designed as a multi-purpose facility with built-in flexibility and the capability to manufacture a complex mix of products.
DNA and RNA phosphoramidites are manufactured in glass-lined reactors and purified by preparative column chromatography on silica gel with medium-to-high pressure chromatography equipment.
SAFC Hamburg has the flexibility to prepare and purify alternative mixes of high volume standard products as well as small scale specialties.
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| The SAFC Hamburg facility also offers: |
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Modern laboratories with state-of-the-art analytical support |
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Integrated solvent delivery |
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A strong background in specialty monomer manufacturing |
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CPG production using the Schott process |
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Extensive storage and warehousing facilities with worldwide distribution services |
Preparative HPLC Purification
| Phosphoramidites are purified at SAFC Hamburg by preparative column chromatography on silica gel with medium to high pressure chromatography equipment. |
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| SAFC Supply Solutions is able to offer: |
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DCM handling capability |
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Integrated solvent delivery |
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> 5000 kg/year amidite purification capacity |
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Three shift operation |
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Automated batch processing |
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State-of-the-art process visualisation |
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Built-in CIP procedures |
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The World's Largest Amidite Manufacturer
SAFC Supply Solutions offers reagents for the synthesis of oligonucleotides including phosphoramidites, controlled pore glass solid supports and liquid formulations.
Annual amidite production capacity is more than five tons, to meet enabling growing industry demands and ensure reliable supply.
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| Large-scale production facilities include: |
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Glass-lined reactors up to 1000 L |
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Multiple mid-size reactor systems from 20 to 200 L |
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Hazardous solvent and reagent handling |
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Integrated solvent delivery from tank farm |
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To order or speak with a Customer Service Representative, contact your local SAFC office. |
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