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New Proligo® Reagents SAFC Supply Solutions® New Products:  2’Fluoro Phosphoramidites  6-FAM 2’Fluoro Phosphoramidites Download Literature: 2'Fluoro Phosphoramidites (425 Kb PDF) As a complement to our existing amidite products, SAFC Supply Solutions adds 2’Fluoro A and G monomers. Key Features of 2’Fluoro Amidites 2'Fluoro amidites are used to synthesize oligonucleotides that are more thermally stable and provide increased nuclease resistance All four bases are available: • DMT-2'Fluoro-dA(bz) Phosphoramidite • DMT-2'Fluoro-dC(ac) Phosphoramidite • DMT-2'Fluoro-dG(ib) Phosphoramidite • DMT-2'Fluoro-dT Phosphoramidite 2'FluoroAmidites can be employed together with DNA and RNA amidites Compatible with deprotection schemes based on methylamine or AMA (conc. aqueous ammonia/40% aqueous methylamine 1/1, v/v) Lot to lot consistent purity and performance Manufactured under a certified ISO 9000:2000 quality system Analytical Specifications of 2'Fluoro Amidites Test 2'F-dA(bz) 2'F-dC(ac) 2'F-dG(ib) 2'F-dU Reverse Phase HPLC ≥98.0% ≥98.0% ≥98.0% ≥98.0% 31P-NMR ≥98% ≥99% ≥98% ≥99% Ordering Information  DMT-2'Fluoro Phosphoramidites  Compatible with Expedite™ and Polygen® Instruments Product No. Description Unit A211281-01 DMT-2'Fluoro-dA(bz) Amidite 1 x 0.25g C213281-01 DMT-2'Fluoro-dC(ac) Amidite 1 x 0.25g G211281-01 DMT-2'Fluoro-dG(ib) Amidite 1 x 0.25g U211281-01 DMT-2'Fluoro-dU Amidite 1 x 0.25g  Compatible with ABI® Instruments A211231-01 DMT-2'Fluoro-dA(bz) Amidite 1 x 0.25g C213231-01 DMT-2'Fluoro-dC(ac) Amidite 1 x 0.25g G211231-01 DMT-2'Fluoro-dG(ib) Amidite 1 x 0.25g U211231-01 DMT-2'Fluoro-dU Amidite 1 x 0.25g Please contact your local sales office for availability and packaging in your country. 6-FAM Download Literature: 6-FAM (414 Kb PDF) 6-FAM as a common fluorescent derivatization reagent for covalent labelling of synthetic oligonucleotides. Key Features of 6-FAM 6-FAM consists of one isomer derived from 6-carboxy fluorescein Couples to the 5'-end of the oligonucleotide using standard synthesis protocols Protecting groups on the fluorescein moiety are removed under standard conditions of cleavage and deprotection with concentrated ammonia A detritylation step is not required since the fluorescein phosphoramidite does not contain a DMT-group The labeled oligonucleotide is ready for use in most applications after the evaporation of ammonia—standard procedures can be used if additional purification is required Lot-to-lot consistent purity and performance Manufactured under a certified ISO 9000:2000 quality system Analytical Specifications of 6-FAM Test 6-FAM HPLC Purity ≥97.0% 31P-NMR ≥97.0% Ordering Information  6-FAM  Compatible with Expedite™ and Polygen® Instruments Product No. Description Unit X010181-01 6-FAM 1 x 0.1g  Compatible with ABI® Instruments X010131-01 6-FAM 1 x 0.1g Please contact your local sales office for availability and packaging in you country.