|
|
|
2'Fluoro Phosphoramidites
| Product Breadth of Proligo Reagents |
|
|
|
|
| Product Breadth of Proligo Reagents |
|
| 2’Fluoro Phosphoramidites are used to synthesize oligonucleotides that are more thermally stable and provide increased nuclease resistance. |
|
View Structures:
DMT-2'Fluoro-dC(ac) Amidite
DMT-2'Fluoro-dU Amidite |
| |
| Key Features of 2'Fluoro Phosphoramidites |
| Can be employed together with DNA or RNA phosphoramidites |
| Recommended deprotection conditions are 8 hours at 55°C using concentrated ammonia solution, or with AMA for 10 minutes at 65°C |
| Synthesis of 2'Fluoro oligonucleotides is similar to standard DNA synthesis, but requires an elongated coupling time (recommended is 3 minutes compared to 90 seconds for DNA monomers) |
| Lot-to-lot consistent high purity and performance |
| Manufactured under a certified ISO 9001 quality system |
|
|
| Analytical Specifications Test |
2'Fluoro-dC(ac) |
2'Fluoro-dU |
| HPLC Purity |
≤98.0% |
≤98.0% |
| 31P-NMR |
≤99.0% |
≤99.0% |
| Phosphoramidites |
| Product Information |
| Product No. |
Description |
Unit |
| C213281-01 |
DMT-2'Fluoro-dC(ac) Amidite - PerkinElmer 8900 & Polygen |
1 x 0.25g |
| C213231-01 |
DMT-2'Fluoro-dC(ac) Amidite, ABI |
1 x 0.25g |
| C213231-01 |
DMT-2'Fluoro-dC(ac) Amidite, ABI |
1 x 1g |
| U211281-01 |
DMT-2'Fluoro-dU Amidite - PerkinElmer 8900 & Polygen |
1 x 0.25g |
| U211231-01 |
DMT-2'Fluoro-dU Amidite, ABI |
1 x 0.25g |
| U211231-01 |
DMT-2'Fluoro-dU Amidite, ABI |
1 x 1g |
SAFC and SAFC Proligo Reagents are registered trademarks of Sigma-Aldrich Biotechnology, LP. ©2009 Sigma-Aldrich Biotechnology LP. All rights reserved. Reproduction forbidden without permission. Other trademarks are the property of their respective owners.
To order or speak with a Customer Service Representative, contact your local SAFC office.
|
|