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DNA Phosphoramidites Proligo® Reagents Product Breadth of Proligo Reagents  Phosphoramidites: Pharmadite® DNA Phosphoramidites RNA Phosphoramidites 2'O-Methyl RNA Phosphoramidites 2'Fluoro Phosphoramidites DMT-2'Fluoro Phosphoramidites 5'-NPPOC Phosphoramidites  Fast Deprotection Chemistries: DNA RNA  Supports: Controlled Pore Glass (CPG) Columns  Solvents: Liquid Reagents Activator 42™  Modifications: Fluorescein Phosphoramidite Biotin Phosphoramidite Phosphate-ON Phosphoramidite Non Standard Nucleosides 6-FAM  Linkers: Amino Linkers ssH Linker Product Breadth of Proligo Reagents Highest Quality SAFC Proligo Reagents’ world-class expertise in nucleic acid synthesis began in 1983 when Dr. Hubert Köster first commercialized the synthesis of ß-cyanoethylphosphoramidites. Since then, the company has refined and perfected the production of DNA and RNA phosphoramidites. Today, SAFC Proligo Reagents® offers the highest quality phosphoramidites in the industry.             Download Literature:   •  User Instructions Pharmadite (217k pdf)   View Structure:   •  DMT-dA(bz) Pharmadite   •  DMT-dC(bz) Pharmadite   •  DMT-dG(ib) Pharmadite   •  DMT-dT Pharmadite Key Features of DNA Phosphoramidites Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)) Recommended cleavage and deprotection conditions are 8 hours at 55°C or 24 hours at room temperature using concentrated ammonia solution, for standard baseprotected oligonucleotides The high coupling efficiency of Proligo Reagents’ DNA phosphoramiditesleads to high-yield, high-quality oligonucleotides     Standard DNA Phosphoramidites Compatible with Expedite™ and Polygen® Instruments Product No. Description Unit A111081-12 DMT-dA(bz) amidite 12 × 1 g A111082-12 DMT-dA(bz) amidite 12 × 2 g C111081-12 DMT-dC(bz) amidite 12 × 1 g C111082-12 DMT-dC(bz) amidite 12 × 2 g G111081-12 DMT-dG(ib) amidite 12 × 1 g G111082-12 DMT-dG(ib) amidite 12 × 2 g T111081-12 DMT-dT amidite 12 × 1 g T111082-12 DMT-dT amidite 12 × 2 g Standard DNA Phosphoramidites Compatible with ABI™ Instruments Product No. Description Unit A111031-12 DMT-dA(bz) amidite 12 × 1 g C111031-12 DMT-dC(bz) amidite 12 × 1 g G111031-12 DMT-dG(ib) amidite 12 × 1 g T111031-12 DMT-dT amidite 12 × 1 g A111032-12 DMT-dA(bz) amidite 12 × 2 g C111032-12 DMT-dC(bz) amidite 12 × 2 g G111032-12 DMT-dG(ib) amidite 12 × 2 g T111032-12 DMT-dT amidite 12 × 2 g A111064-12 DMT-dA(bz) amidite 12 × 4 g C111064-12 DMT-dC(bz) amidite 12 × 4 g G111064-12 DMT-dG(ib) amidite 12 × 4 g T111064-12 DMT-dT amidite 12 × 4 g Compatible with Mermade™ Instruments (8oz 28/400 bottle) Product No. Description Unit A111085-06 DMT-dA(bz) amidite 6 × 5 g C111085-06 DMT-dC(bz) amidite 6 × 5 g G111085-06 DMT-dG(ib) amidite 6 × 5 g T111085-06 DMT-dT amidite 6 × 5 g A111028-06 DMT-dA(bz) amidite 6 × 10 g C111028-06 DMT-dC(bz) amidite 6 × 10 g G111028-06 DMT-dG(ib) amidite 6 × 10 g T111028-06 DMT-dT amidite 6 × 10 g Compatible with AKTA™ Oligo Pilot Instruments (100ml septum bottle) Product No. Description Unit A111005-01 DMT-dA(bz) amidite 5 g A111005-06 DMT-dA(bz) amidite 6 × 5 g A111010-01 DMT-dA(bz) amidite 10 g A111020-06 DMT-dA(bz) amidite 6 × 20 g C111005-01 DMT-dC(bz) amidite 5 g C111005-06 DMT-dC(bz) amidite 6 × 5 g C111010-01 DMT-dC(bz) amidite 10 g C111020-06 DMT-dC(bz) amidite 6 × 20 g G111005-01 DMT-dG(ib) amidite 5 g G111005-06 DMT-dG(ib) amidite 6 × 5 g G111010-01 DMT-dG(ib) amidite 10 g G111020-06 DMT-dG(ib) amidite 6 × 20 g T111005-01 DMT-dT amidite 5 g T111005-06 DMT-dT amidite 6 × 5 g T111010-01 DMT-dT amidite 10 g T111020-06 DMT-dT amidite 6 × 20 g Bulk Quantities (16oz 28/400 bottle) Product No. Description Unit A111005-01 DMT-dA(bz) amidite 5 g A111005-06 DMT-dA(bz) amidite 6 × 5 g A111010-01 DMT-dA(bz) amidite 10 g A111020-06 DMT-dA(bz) amidite 6 × 20 g C111005-01 DMT-dC(bz) amidite 5 g C111005-06 DMT-dC(bz) amidite 6 × 5 g C111010-01 DMT-dC(bz) amidite 10 g C111020-06 DMT-dC(bz) amidite 6 × 20 g G111005-01 DMT-dG(ib) amidite 5 g G111005-06 DMT-dG(ib) amidite 6 × 5 g G111010-01 DMT-dG(ib) amidite 10 g G111020-06 DMT-dG(ib) amidite 6 × 20 g T111005-01 DMT-dT amidite 5 g T111005-06 DMT-dT amidite 6 × 5 g T111010-01 DMT-dT amidite 10 g T111020-06 DMT-dT amidite 6 × 20 g Custom Products Bulk packaging up to multiple kg per container and customized packaging with alternative quantities of amidites are available upon request. SAFC and SAFC Proligo Reagents are trademarks of Sigma-Aldrich Biotechnology, LP. ©2009 Sigma-Aldrich Biotechnology LP. All rights reserved. Reproduction forbidden without permission. Other trademarks are the property of their respective owners. To order or speak with a Customer Service Representative, contact your local SAFC office.