Sheboygan, Wisconsin

Chemical Manufacturing

Complex multi-step organic synthesis, air-sensitive compounds and high-purity solvent manufacturing are specialties at our 513 acre, five production area Sheboygan, Wisconsin, manufacturing site. This facility enables us to provide a complete range of services to customers - from process development to pilot plant and commercial scale production.

Core Competencies

  • Multi-step and air sensitive synthesis, gram to metric ton scale, non-GMP
  • Cryogenic to high temperature reactions (-100 to +250 °C)
  • High-purity organics and organometallics
  • Monomer synthesis and purification
  • Purification and packaging of solvents
  • High-purity electronic precursors
  • Process development
  • Analytical development
  • Hazard Evaluation

Core Technologies

  • 30 gal to 4000 gal fixed reactors (stainless steel, Hastelloy®, or glass lined)
  • Distillation capabilities from 1L to 1000 gal
  • Continuous flow chemistry
  • Phosgenations
  • Hydrogenations & high pressure reactions
  • Ozonolysis
  • Clean room suite (ISO Class 3); Dedicated rooms for high-purity packaging and trace metal analysis
  • Custom packaging

Capabilities Overview

  • Sheboygan electronic chemical manufacturing:
    Production II Bay A:
    - Large-scale Manufacturing Production A
    - Large-scale, non-cGMP manufacturing for organic compounds
  • Production III – Intermediate-Scale Air-Sensitive Manufacturing:
    Specialized production for medium-scale manufacturing of air-sensitive materials, to include dedicated distillation suite for final purification step of high purity products
  • Production IV – Solvents / High Purity Organics Purification
  • Large-scale solvent and high-purity organics purification
  • Clean I – Cleanroom for packaging and trace metal analysis
  • Clean room suite that can sustain operations at ISO Class 3. Dedicated rooms for container preparation and fill. Trace metals analysis with sample preparation and instrumentation rooms.
  • Monomer Synthesis & Purification
  • Continuous Flow Manufacturing

Virtual Tours

Industrial Scale Air Sensitives

Intermediate Scale Air Sensitives

Large Scale Organics

High Purity Organics

Process Develpment

Quality Control

Contact Facility

Facility Address:
5485 County Road V
Sheboygan Falls, WI 53085, USA
Tel: 800-448-0471
Email: safchitechcustomerservice@sial.com

Certificates & Documents
Request a Site Audit

Reach out directly to our team here to process / schedule your site audit.