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RNAi Opportunities
Lentiviral delivery technology
Patent (364 Kb PDF)
Sigma-Aldrich Corporation is the exclusive worldwide licensee of U.S. Pat. Nos. 5,817,491; 5,591,624; 5,716,832; 6,312,682; 6,669,936; 6,235,522; 6,924,123 and foreign equivalents from Oxford Biomedica Ltd., Oxford, UK.
DNA-directed RNA interference
Patent (56 Kb PDF)
Sigma-Aldrich Corporation is also the exclusive worldwide licensee for certain fields of U.S. Pat. No. 6,573,099 and foreign counterparts co-owned by Benitec Australia, Ltd. and the Australian Commonwealth Scientific and Industrial Research Organization (CSIRO) both of Australia.
Sigma-Aldrich is making available sublicenses of the licensed patents as well as making available licensed Lentivirus-based shRNA Libraries for purchase through its catalog and web sites.
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For a commercial license to the DNA-directed RNA interference IP, please visit the Benitec Web site. |
FLAG® Opportunities
Multiple Epitopes for Identification and Purification of Recombinant Proteins and
FLAG / ANTI-FLAG Trademarks |
Cleavable Multiple-FLAG (DYKDDDDK) epitope-tag expression and purification technology.
Use of FLAG / Anti-FLAG trademarks. |
| Discovery Tools |
• Primary Screening
• Secondary Screening (e.g. cell biological profiling or high content screening)
• Target Discovery (proteomic or genomic based)
• Target Validation (proteomic or genomic based)
• Protein Expression |
Marketing Rights
Available/Desired |
• Worldwide |
| Publications |
• US Patent 6,379,903 (459 Kb PDF) |
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HIS-Select® Opportunities
| HIS-Select Metal Chelate Composition & iLAP™ (Integrated Lysis and Purification) Technologies |
| HIS-Select technology is a proprietary metal chelate with superior specificity over conventional nitrilotriacetic acid resins. iLAP is combined solid phase cell lysis and purification platform. Both technologies are also trademark registered. |
| Discovery Tools |
• Protein Expression |
Marketing Rights
Available/Desired |
• Worldwide |
| Publications |
• Patents: US 7,033,520 (799 Kb PDF); US 6,623,655 (998 Kb PDF);
US 20060148090 (787 Kb PDF); US 20040092031 (773 Kb PDF);
US 20040259162 (2.5 Mb PDF) |
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REDTaq® & REDAccuTaq® Opportunities
| REDTaq and REDAccuTaq are based on an invention using tracer reagents to enhance PCR and RT-PCR reaction-product analysis enabling simple direct gel loading for visualization. |
| Discovery Tools |
• Genomics |
Marketing Rights
Available/Desired |
• Worldwide |
| Publications |
• Relevant patent and patent applications: US 6,942,964 (1.3 Mb PDF);
US20050148009 (1.2 Mb PDF); US20050148010 (1.2 Mb PDF);
US20050148011 (1.2 Mb PDF). REDTaq and REDAccuTaq are registered
trademarks of Sigma-Aldrich |
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Whole Genome Amplification Opportunities
| Whole Genome Amplification Technology |
| Discovery Tools |
• Pharmacogenetics/genomics |
Marketing Rights
Available/Desired |
• Worldwide |
| Field of use restriction |
• Research use and service providers |
| Publications |
• US Patent Application No. 10/795,667 (7.2 Mb PDF)
International Application No. PCT/US204/00693 Titled "Amplification and
Analysis of Whole Genome and Whole Transcriptome Libraries Generated
by a DNA Polymerization Process" |
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Whole Transcriptome Amplification Opportunities
| Whole Transcriptome Amplification Technology |
| Discovery Tools |
• Pharmacogenetics/genomics |
Marketing Rights
Available/Desired |
• Worldwide |
| Field of use restriction |
• Research use and service providers |
| Publications |
• US Patent Application No. 10/795,667 (7.2 Mb PDF)
International Application No. PCT/US204/00693 Titled "Amplification and
Analysis of Whole Genome and Whole Transcriptome Libraries Generated
by a DNA Polymerization Process" |
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Chemistry Opportunities
Borane-Sulfide Hydroboration Agents
US Patent 5567849 (465 Kb PDF)
Dioxane-Monochloroborane and Dioxane-Dichloroborane
US Patent 6008414 (386 Kb PDF)
Stabilized Borane-Tetrahydrofuran Complex
US Patent 7767833 (951 Kb PDF)
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For more information, please contact:
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