HPLC Analysis of Aminoglutethimide Enantiomers on Astec® Cellulose DMP

HPLC Analysis of Aminoglutethimide Enantiomers on Astec® Cellulose DMP

Conditions

column Astec Cellulose DMP; 25 cm x 4.6 mm I.D., 5 µm particles (51099AST)
column temp. 30 °C
mobile phase [A] heptane; [B] isopropanol; [C] diethylamine; (70:30:0.1, A:B:C)
flow rate 1 mL/min
sample aminoglutethimide, 1 g/L in 50:50, heptane:isopropanol
injection 15 µL

Description

Analysis Note Aminoglutethimide enantiomers are resolved by normal phase chromatography.
Categories Analytical Chromatography, Antineoplastics, Anticholesterolemics
Featured Industry Pharmaceutical (small molecule)
Legal Information Astec is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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