HPLC Analysis of Glutethimide Enantiomers on Astec® Cellulose DMP

HPLC Analysis of Glutethimide Enantiomers on Astec® Cellulose DMP

Conditions

column Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 µm particles (51099AST)
column temp. 30 °C
mobile phase [A] heptane; [B] isopropanol; (80:20, A:B)
flow rate 1 mL/min
sample glutethimide, 1 g/L in heptane:isopropanol (50:50)
injection 15 µL
detector UV, 254 nm

Description

Analysis Note Glutethimide enantiomers are resolved by normal phase chromatography.
Categories Analytical Chromatography, Forensics and Toxicology, Chiral Applications, drugs of abuse, anxiolytics/sedatives, Clinical, Forensic & Toxicology, Drugs of Abuse
Featured Industry Forensics and Toxicology
Pharmaceutical (small molecule)
Legal Information Astec is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes Glutethimide is used to treat insomnia.
suitability application for HPLC

Materials

     
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