HPLC Analysis of α-Pyrrolidinobutiophenone (PBP) Enantiomers on Astec® CHIROBIOTIC® V2

HPLC Analysis of α-Pyrrolidinobutiophenone (PBP) Enantiomers on Astec® CHIROBIOTIC® V2

Conditions

column Astec CHIROBIOTIC V2, 15 cm x 4.6 mm I.D., 5 µm particles (15023AST)
column temp. 20 °C
mobile phase [A] methanol; [B] water; [C] acetic acid; [D] ammonium hydroxide; (95:5:0.1:0.02, A:B:C:D)
flow rate 1 mL/min
pressure 1100 psi (70 bar)
sample 100 µg/mL in methanol
injection 5 µL
detector UV, 251 nm

Description

Analysis Note a-Pyrrolidinobutiophenone, also known as a-PBP, is a designer stiµLant with reported instances of abuse in Europe and the United States. Astec CHIROBIOTIC V2, based on vancomycin CSP, provided resolution of the enatiomers. CRMs from Cerillliant provided reliable identification and quantification.
Categories Analytical Chromatography, Drugs of Abuse
Featured Industry Forensics and Toxicology
Legal Information CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC, Astec is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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