HPLC Analysis of Typical Parent Antipsychotic Drugs Using a Titan™ C18 Column

HPLC Analysis of Typical Parent Antipsychotic Drugs Using a Titan™ C18 Column

Conditions

column Titan C18, 10 cm  x 3.0 mm, 1.9 µm particles (577132-U)
column temp. 35 °C
mobile phase [A] 0.1% formic acid in water, [B] 0.1% formic acid in methanol
gradient 25% B for 2 minutes followed by a linear gradient to 95% B for 10 minutes, followed by a hold at 95% B for 2 minutes.
flow rate 0.5 mL/min
sample 25 µg/mL each in 10% methanol
injection 2 µL
detector UV, 254 nm

Description

Analysis Note An application was developed on Titan C18 to separate typical parent antipsychotics.
Categories Analytical Chromatography, Antipsychotics
Featured Industry Pharmaceutical (small molecule)
Legal Information Titan is a trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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